Rat aortic smooth muscle cell density affects activation of map kinase and Akt by menadione and PDGF homodimer BB

Journal of Surgical Research

Volumn 100, Issue 2, 2001, Pages 197-204

  Li, X Alec ^a,b   Bianchi, Cesario ^a   Sellke, Frank W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Atherosclerosis; Cross talk; Growth factors; Oxidative stress; Restenosis

Indexed keywords

CALCIUM CHELATING AGENT; EDETIC ACID; EGTAZIC ACID; MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; SYNAPTOPHYSIN;

ANIMAL CELL; AORTA MEDIA; APOPTOSIS; ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; REDUCTION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

EID: 0034771426     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2001.6238     Document Type: Article

References (20)

1. Atherosclerosis - An inflammatory disease
2. Determinants of vascular smooth muscle cell apoptosis after balloon angioplasty injury. Influence of redox state and cell phenotype
3. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF
4. 2+
5. - production in the pig coronary artery
6. Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
7. A redox-signaling mechanism for density-dependent inhibition of cell growth
8. Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells
9. Growth factors and mitogen-activated protein kinases
10. 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2
11. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: Role in mediating airway smooth muscle proliferation
12. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
13. Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
14. Negative regulation of the serine/threonine kinase B-Raf by Akt
15. Phosphorylation and regulation of Raf by Akt (protein kinase B)
16. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt
17. Menadione-induced oxidative stress potentiates PDGFBB activation of MAPK in vascular smooth muscle cells. A cross-talk between oxidant- and peptide growth factor-mediated signal transduction
18. Superoxide-mediated tyrosine phosphorylation in rat aortic smooth muscle cells (RASMC): Possible signal transduction pathway for oxidative stress
19. Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase
20. Signal transduction mechanisms linking increased extracellular calcium to proliferation in ovarian surface epithelial cells