Endothelial KCa channels mediate flow-dependent dilation of arterioles of skeletal muscle and mesentery

Microvascular Research

Volumn 61, Issue 2, 2001, Pages 179-186

  Sun, Dong ^a   Huang, An ^a   Koller, Akos ^a   Kaley, Gabor ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Endothelial KCa channels; Flow shear stress; Mechanotransduction; Microvessels

Indexed keywords

ACETYLCHOLINE; CALCIUM; IBERIOTOXIN; NITROPRUSSIDE SODIUM; POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTERIOLE; ARTERY DIAMETER; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; CREMASTER MUSCLE; GRACILIS MUSCLE; INTESTINE PRESSURE; MESENTERY; MICROVASCULATURE; MUSCLE BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; RAT; SHEAR STRESS;

EID: 0034770514     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.2000.2291     Document Type: Article

References (34)

1. Ion channels and regulation of intracellular calcium in vascular endothelial cells
2. Phospholipase C: A putative mechanotransducer for endothelial cell response to acute hemodynamic changes
3. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
4. Flow-mediated endothelial mechanotransduction
5. + channels contribute to vascular tone
6. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium
7. Endothelial cell calcium increases during flow-induced dilation in isolated arterioles
8. Flow effects on prostacyclin production by cultured human endothelial cells
9. + channels mediate EDRF release to flow but not agonists in rabbit aorta
10. Mechanotransduction through the endothelial cytoskeleton: Mediation of flow-but not agonist-induced EDRF release
11. + channels in arteriolar muscle cells
12. Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells
13. Flow velocity-dependent regulation of microvascular resistance in vivo
14. Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles
15. Role of shear stress and endothelial prostaglandins in flow and viscosity-induced dilation of arterioles in vitro
16. 1251] Iberiotoxin - D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels
17. Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells
18. Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels
19. Endothelium dependent, flow induced dilation of isolated coronary arterioles
20. Impaired nitric oxide and prostaglandin-mediated responses to flow in resistance arteries of hypertensive rats
21. Nitric oxide does not mediate flow induced endothelium dependent arterial dilation in the cat
22. Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles
23. Coronary arteriolar flow-induced vasodilation signals through tyrosine kinase
24. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
25. 2+
26. Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling
27. + current in vascular endothelial cells
28. 2+ sensitivity and block
29. Dilator response of rat mesenteric arcading arterioles to increased blood flow velocity
30. + channel blockade inhibits shear stress-induced pulmonary vasodilation in the ovine fetus
31. Characteristics and origin of the myogenic response in isolated gracilis muscle arterioles
32. Flow-dependent dilation of arterioles is abolished by blockade of endothelial microtubule assembly
33. Characteristics and origins of the myogenic response in isolated mesenteric arterioles
34. Effects of perfusion and endothelium on the reactivity of isolated resistance arteries