Role of penicillin-binding protein 4 in expression of vancomycin resistance among clinical isolates of oxacillin-resistant Staphylococcus aureus

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 11, 2001, Pages 3070-3075

  Finan, J E ^a   Archer, G L ^a   Pucci, M J ^a   Climo, M W ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXACILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 4; UNCLASSIFIED DRUG; VANCOMYCIN;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIUM ISOLATION; CROSS LINKING; DNA FLANKING REGION; GENE STRUCTURE; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; STRAIN DIFFERENCE;

BACTERIAL PROTEINS; CARRIER PROTEINS; CULTURE MEDIA; DNA, BACTERIAL; HEXOSYLTRANSFERASES; HUMANS; MICROBIAL SENSITIVITY TESTS; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; MUTATION; OXACILLIN; PENICILLIN RESISTANCE; PENICILLIN-BINDING PROTEINS; PEPTIDOGLYCAN; PEPTIDYL TRANSFERASES; PHENOTYPE; PLASMIDS; SEQUENCE DELETION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VANCOMYCIN RESISTANCE;

EID: 0034769882     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.11.3070-3075.2001     Document Type: Article

References (26)

1. A spectrum of changes occurs in peptidoglycan composition of glycopeptide-intermediate clinical Staphylococcus aureus isolates
2. Comparison of the in vitro and in vivo efficacy of FKO37, vancomycin, imipenem, and nafcillin against staphylococcal species
3. Identification and characterization of the origin of conjugative transfer (oriT) and a gene (nes) encoding a single-stranded endonuclease on the staphylococcal plasmid pGO1
4. Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50
5. Transcription analysis of the Staphylococcus aureus gene encoding penicillin-binding protein 4
6. Altered production of penicillin-binding protein 2a can affect phenotypic expression of methicillin resistance in Staphylococcus aureus
7. Activated cell-wall synthesis is associated with vancomycin resistance in methicillin-resistant Staphylococcus aureus clinical strains Mu3 and Mu50
8. Penicillin-binding protein 4 overproduction increases beta-lactam resistance in Staphylococcus aureus
9. Staphylococcus aureus penicillin-binding protein 4 and intrinsic beta-lactam resistance
10. Effects of penicillin-binding protein 4 overproduction in Staphylococcus aureus
11. The emergence of Staphylococcus aureus with reduced susceptibility to vancomycin in Japan
12. A membrane enzyme from Staphylococcus aureus which catalyzes transpeptidase, carboxypeptidase, and penicillinase activities
13. Role of mecA transcriptional regulation in the phenotypic expression of methicillin resistance in Staphylococcus aureus
14. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus
15. Characterization of passage-selected vancomycin-resistant Staphylococcus aureus strains of diverse parental backgrounds
16. Improved method for electroporation of Staphylococcus aureus
17. Interaction of native and mutant MecI repressors with sequences that regulate mecA, the gene encoding penicillin binding protein 2a in methicillin-resistant staphylococci
18. Inactivated pbp4 in highly glycopeptide-resistant laboratory mutants of Staphylococcus aureus
19. Gradual alterations in cell wall structure and metabolism in vancomycin-resistant mutants of Staphylococcus aureus
20. Suppression of glycopeptide resistance in a highly teicoplanin-resistant mutant of Staphylococcus aureus by transposon inactivation of genes involved in cell wall synthesis
21. Inactivation of the methicillin resistance gene mecA in vancomycin-resistant Staphylococcus aureus
22. Emergence of vancomycin resistance in Staphylococcus aureus
23. Cross-linking and O-acetylation of peptidoglycan in Staphylococcus aureus (strains H and MR-1) grown in the presence of sub-growth-inhibitory concentrations of beta-lactam antibiotics
24. Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus
25. A role in vivo for penicillin-binding protein-4 of Staphylococcus aureus