Evaluation of creatine transport using Caco-2 monolayers as an in vitro model for intestinal absorption

Journal of Pharmaceutical Sciences

Volumn 90, Issue 10, 2001, Pages 1593-1598

  Dash, Alekha K ^a   Miller, Donald W ^b   Huai Yan, Han ^c   Carnazzo, Joe ^a   Stout, Jeffrey R ^a  

^a CREIGHTON UNIVERSITY   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^c Fortress Systems International   (United States)

Author keywords

Caco 2 cell monolayer; Creatine monohydrate; Transport

Indexed keywords

CREATINE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CELL STRAIN CACO 2; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION;

EID: 0034768635     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.1109     Document Type: Article

References (17)

1. Effects of creatine supplementation on body composition, strength, and sprint performance
2. Creatine supplementation favorable: Affects performance and muscle metabolism during maximal exercise in humans
3. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation
4. Influence of oral creatine supplementation of muscle torque during repeated bouts of maximal voluntary exercise in man
5. Creatine supplementation and dynamic high-intensity intermittent exercise
6. The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength, and body composition
7. Carbohydrate ingestion augments creatine retention during creatine feeding in humans
8. Effects of ingesting supplements designed to promote lean tissue accretion on body composition during resistance training
9. The nutritional biochemistry of creatine
10. Development of a rectal nicotine delivery system for the treatment of ulcerative colitis
11. The equilibrium between creatine and creatinine, in aqueous solution: The effect of hydrogen ion
12. The creatine-creatinine equilibrium: The apparent dissociation constants of creatine and creatinine
13. Pluronic P85 increases the permeability of a broad spectrum of drugs in polarized BBMEC and caco-2 cell monolayers
14. Responses of beta-adrenoceptor in rat soleus to phosphorus compound levels and/or unloading