Ordered array of dendritic cells and CD8+ lymphocytes in portal infiltrates in chronic hepatitis C

Histopathology

Volumn 39, Issue 4, 2001, Pages 373-381

  Galle M B ^a   DeFranco, R M S ^a   Kerjaschki, D ^b   Romanelli, R G ^a   Montalto, P ^a   Gentilini, P ^a   Pinzani, M ^a   Romagnoli, P ^a,c  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF VIENNA   (Austria)

^c Departments of Anatomy Histology and Forensic Medicine   (Italy)

Author keywords

Chronic hepatitis; Dendritic cells; Electron microscopy; Hepatitis C virus; Immunohistochemistry; Lymphatic capillaries; Lymphocytes

Indexed keywords

B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; MEMBRANE ANTIGEN;

ADULT; AGED; ARTICLE; CELL INFILTRATION; CELL ULTRASTRUCTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; ELECTRON MICROSCOPY; FEMALE; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LIVER BIOPSY; LIVER CELL; LYMPH VESSEL ENDOTHELIUM; MALE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; AGED; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, CD86; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FEMALE; HEPATITIS C, CHRONIC; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MIDDLE AGED;

HEPATITIS C VIRUS;

EID: 0034767867     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.2001.01241.x     Document Type: Article

References (41)

1. The lymphocyte-dendritic cell system
2. Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes
3. Role of dendritic cells in the priming of CD4+ T-lymphocytes to peptide antigen in vivo
4. Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence ofCD4+ helper T-cells
5. Dendritic cells process exogenous viral proteins and virus-like particles for class I presentation to CD8(+) cytotoxic T lymphocytes
6. Immature dendritic cells phagocytose apoptotic cells via alpha(v)beta(5) and CD36, and cross-present antigens to cytotoxic T lymphocytes
7. Generation of primary peptide-specific CD8(+) cytotoxic T-lymphocytes in vitro using allogeneic dendritic cells
8. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can regulate dendritic cell-induced activation and cytotoxicity CD8(+) T cells independently of CD4(+) T cell help
9. Induction of primary human CD8(+) T lymphocyte responses in vitro using dendritic cells
10. In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes
11. Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations
12. B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells
13. Blockade of costimulatory molecules B7-1 (CD80) and B7-2 (CD86) down- regulates induction of contact sensitivity by haptenated epidermal cells
14. Dendritic cells in the dermal infiltrate of Sézary syndrome
15. Morphology and membrane antigens of non-lymphoid accessory cells in oral hairy leukoplakia
16. Dendritic cells in the skin after allogeneic bone marrow transplantation: Immunohistochemical and electron microscopic monitoring
17. Dendritic cells in cutaneous lupus erythematosus: A hint to the pathogenesis of lesions
18. Characterization of interstitial dendritic cells in human liver
19. Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance
20. Immunological aspects of chronic active hepatitis
21. Interdigitating and dendritic reticulum cells in chronic active hepatitis
22. Primary biliary cirrhosis (PBC): Antigen presenting cells differ in their distribution in early and late stage PBC and involve the ductal, but not the ductular compartment
23. Primary biliary cirrhosis. Localization of antigen-presenting cells in piecemeal necrosis
24. B7-2 positive cells around interlobular bile ducts in primary biliary cirrhosis and chronic hepatitis C
25. In situ distribution of major histocompatibility complex products and viral antigens in chronic hepatitis B virus infection: Evidence that HBc-containing hepatocytes may express HLA-DR antigens
26. S100 protein positive dendritic cells in primary biliary cirrhosis and other chronic inflammatory liver diseases: Relevance to pathogenesis?
27. Dendritic cells and the liver
28. Initiation of the autologous mixed lymphocyte reaction requires the expression of costimulatory molecules B7-1 and B7-2 on human peripheral blood dendritic cells
29. The role of B7 costimulation in T-cell immunity
30. Immunohistochemical localization of antigen presenting cells in liver from patients with primary biliary cirrhosis; highly restricted distribution of CD83-positive activated dendritic cells
31. Morphometric analysis of lymphatic and blood vessels in human chronic viral liver diseases
32. Classification of chronic viral hepatitis: A need for reassessment
33. Formulation and application of a numerical scoring system for assessing histolog- ical activity in asymptomatic chronic active hepatitis
34. Angiosarcomas express mixed endothelial phenotypes of blood lymphatic capillaries. Podoplanin as a specific marker for lymphatic endothelium
35. Intrapericardial lymphangioma with podoplanin immunohistochemical characterization of lymphatic endothelial cells
36. Dendritic cells and the dermis
37. Dendritic cells enhance the differentiation of naive B cells into plasma cells in vitro
38. Dendritic cells associated with plasmablast survival
39. A member of the dendritic cell family that enters B cell follicles and stimulates primary antibody responses identified by a mannose receptor fusion protein
40. Dendritic cells capable of stimulating T cells in germinal centres