Characterization of the macromolecule baseline in localized 1H-MR spectra of human brain

Magnetic Resonance in Medicine

Volumn 46, Issue 5, 2001, Pages 855-863

  Hofmann, L ^a   Slotboom, J ^a   Boesch, C ^a   Kreis, R ^a,b  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Aging; Brain; Lipids; Macromolecules; MR spectroscopy; Quantitation

Indexed keywords

AGING OF MATERIALS; BIOMOLECULES; BRAIN; LIPIDS; MAGNETIC RESONANCE; MAGNETIC RESONANCE SPECTROSCOPY; METABOLITES; RECOVERY;

CLINICAL INFORMATION; INVERSION RECOVERY; LOW MOLECULAR WEIGHT; MAGNETIC RESONANCE SPECTRA; METABOLITE SPECTRA; MR SPECTROSCOPY; QUANTITATION; SIMULTANEOUS RECORDING;

MACROMOLECULES;

LIPID;

ADULT; AGED; AGING; ARTICLE; BRAIN; CHEMICAL COMPOSITION; FEMALE; HUMAN; LIPID BRAIN LEVEL; MACROMOLECULE; MALE; NORMAL HUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ASSAY; TECHNIQUE;

EID: 0034766440     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1269     Document Type: Article

References (30)

1. Analysis of macromolecule resonances in 1H NMR spectra of the brain
2. Absolute quantitation of water and metabolites in the human brain. II. Metabolite concentrations
3. Development of the human brain: In vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy
4. Analysis of biological NMR relaxation data with continuous distributions of relaxation times
5. Quantitative interpretation of NMR relaxation data
6. Application of continuous relaxation time distributions to the fitting of data from model systems and excised tissue
7. 1
8. Quantitative characterization of the macromolecule baseline in cerebral 1H-MR spectra determined by saturation and inversion recovery methods
9. The application of phase rotation for localized in vivo proton spectroscopy with short echo times
10. Improved water suppression for localized in vivo 1H spectroscopy
11. Spectral fitting in a constrained parameter space using a random search strategy and prior knowledge
12. Model fitting of 1H-MR spectra of the human brain: Incorporation of short-T1 components and evaluation of parameterized vs. non-parameterized models
13. Absolute quantitation of water and metabolites in the human brain. I. Compartments and water
14. 1H-MR spectroscopy for clinical use
15. Discrimination of metabolite from lipid and macromolecule resonances in cerebral infarction in humans using short echo proton spectroscopy
16. 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: Implications for the in vivo detection of apoptosis
17. 1H NMR visible lipids in the life and death of cells
18. Improved sensitivity to overlapping multiplet signals in in vivo proton spectroscopy using a multiecho volume selective (CPRESS) experiment
19. Application of multiple inversion recovery for suppression of macromolecule resonances in short echo time (1)H NMR spectroscopy of human brain
20. Characterization of macromolecule resonances in the 1H NMR spectrum of rat brain
21. Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain
22. Estimation of metabolite concentration from localized in vivo proton NMR spectra
23. Automated spectral analysis. III. Application to in vivo proton MR spectroscopy and spectroscopic imaging
24. Toward an in vivo neurochemical profile: Quantification of 18 metabolites in short-echo-time 1-H NMR spectra of the rat brain
25. 1H-MR spectra of human white and gray matter
26. 1H MR spectra of the human brain at 3 T
27. Hypoxic encephalopathy after near-drowning studied by quantitative 1H-magnetic resonance spectroscopy: Metabolic changes and their prognostic value
28. Two-dimensional fitting with prior knowledge constraints: The solution for glutamate/glutamine quantitation at 1.5T?
29. Elimination of artifacts in short echo time 1H MR spectroscopy of the frontal lobe