Synaptotagmin IV: Biochemistry genetics, behavior, and possible links to human psychiatric disease

Molecular Neurobiology

Volumn 23, Issue 2-3, 2001, Pages 173-185

  Shobana, S ^a   Akhilender Naidu, K ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

Depolarization inducible; Hippocampus; Learning and memory; Schizophrenia; Synaptic plasticity; Synaptotagmin IV

Indexed keywords

COMPLEMENTARY DNA; SYNAPTOTAGMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMOSOME 18; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; HUMAN; LEARNING; MANIC DEPRESSIVE PSYCHOSIS; MEMORY; MENTAL DISEASE; MOTOR COORDINATION; MOUSE MUTANT; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN DOMAIN; PROTEIN INDUCTION; RAT; SCHIZOPHRENIA;

EID: 0034765065     PISSN: 08937648     EISSN: None     Source Type: Journal    
DOI: 10.1385/MN:23:2-3:173     Document Type: Article

References (67)

1. Synaptic plasticity and memory: An evaluation of the hypothesis
2. Long-lasting potentiation of synaptic transmission in the dentate area of the unanaestetized rabbit following stimulation of the perforant path
3. Synaptic model of memory: Long-term potentiation in the hippocampus
4. Fear conditioning induces associative long-term potentiation in the amygdala
5. Chemical studies on memory fixation in goldfish
6. Requirement of a critical period of transcription for induction of a late phase of LTP
7. Primary response genes induced by growth factors and tumor promoters
8. Searching for depolarization-induced genes that modulate synaptic plasticity and neurotrophin-induced genes that mediate neuronal differentiation
9. Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
10. Rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Rasrelated protein
11. Numerous candidate plasticity-related genes revealed by differential cDNA cloning
12. Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation
13. The urokinase plasminogen activator receptor (UPAR) is preferentially induced by nerve growth factor in PC12 pheochromocytoma cells and is required for NGF-driven differentiation
14. ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion
15. Synaptotagmins: More isoforms than functions?
16. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
17. Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C
18. Functional properties of multiple synaptotagmins in brain
19. Synaptotagmins: C2-domain proteins that regulate membrane traffic
20. Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
21. Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca(2+)-activated neurotransmitter release
22. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin
23. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans
24. Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain
25. The human synaptotagmin IV gene defines an evolutionary breakpoint between syntenic mouse and human chromosome regions, but retains ligand inducibility and tissue specificity
26. Two synaptotagmin genes, Syt1 and Syt4, are differentially regulated in adult brain and during postnatal development following kainic acid-induced seizures
27. Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
28. Ca2+ regulates the interaction between synaptotagmin and syntaxin 1
29. The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding
30. Synaptic function modulated by changes in the ratio of synatotagmin I and IV
31. A third synaptotagmin gene, Syt3, in the mouse
32. Functional and biochemical analysis of the C2 domains of synaptotagmin IV
33. Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin
34. Ca(2+)-dependent dependent and -independent activities of neural and non-neural synaptotagmins
35. Developmental regulation of synaptotagmin I, II, III, and IV mRNAs in the rat CNS
36. Synthesis degradation, and subcellular localization of synaptotagmin IV, a neuronal immediate early gene product
37. Synaptotagmin IV is present at the Golgi and distal parts of neurites
38. Calcium-dependent oligomerization of synaptotagmins I and II. Synaptotagmins I and II are localized on the same synaptic vesicle and heterodimerize in the presence of calcium
39. Synaptotagmin I and IV define distinct populations of neuronal transport vesicles
40. The subcellular localizations of atypical synaptotagmins III and VI. Synaptotagmin III is enriched in synapses and synaptic plasma membranes but not in synaptic vesicles
41. Deficits in memory and motor performance in synaptotagmin IV mutant mice
42. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
43. Temporally graded retrograde amnesia of contextual fear after hippocampal damage in rats: Within-subjects examination
44. The dorsal hippocampus is essential for context discrimination but not for contextual conditioning
45. Naloxone and shock-elicited freezing in the rat
46. Modality-specific retrograde amnesia of fear
47. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
48. Selective damage to the hippocampal region blocks longterm retention of a natural and nonspatial stimulus-stimulus association
49. Neural substrates for conditioned taste aversion in the rat
50. Report of the chromosome 18 workshop
51. Psychiatric disorder in a familial 15;18 translocation and sublocalization of myelin basic protein of 18q22.3
52. Susceptibility loci for bipolar disorder: Overlap with inherited vulnerability to schizophrenia
53. Forms of memory failure in schizophrenia
54. Dopamine as the wind of the psychotic fire: New evidence from brain imaging studies
55. Signal transmission, rather than reception, is the underlying neurochemical abnormality in schizophrenia
56. Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders
57. Levels of mRNAs encoding synaptic vesicle and synaptic plasma membrane proteins in the temporal cortex of elderly schizophrenic patients
58. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
59. Comparison of two forms of long-term potentiation in single hippocampal neurons
60. Cyclic AMP mediates a presynaptic form of LTP at cerebellar parallel fiber synapses
61. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos
62. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons
63. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism
64. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
65. Inducible and reversible gene expression with the rtTA system for the study of memory
66. Acute administration of cocaine, but not amphetamine, increases the level of synaptotagmin IV mRNA in the dorsal striatum of rat
67. Is there solid evidence for reorganization of the neural network associated with development of behavioral sensitization to psychostimulants?