Contribution of CYP1A2 in the hepatic metabolism of melatonin: Studies with isolated microsomal preparations and liver slices

Journal of Pineal Research

Volumn 31, Issue 4, 2001, Pages 333-342

  Skene, Debra J ^a   Papagiannidou, Eleni ^a   Hashemi, Elham ^a   Snelling, Jacquie ^a   Lewis, David F V ^a   Fernandez, Michelle ^a   Ioannides, Costas ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

6 Sulphatoxymelatonin; CYP1A2; Cytochrome P450; Enzyme induction; Liver slices; Melatonin

Indexed keywords

6 HYDROXYMELATONIN O SULFATE; ACETONE; BETA NAPHTHOFLAVONE; CLOFIBRATE; CYTOCHROME P450 1A2; DEXAMETHASONE; DRUG METABOLIZING ENZYME; FURAFYLLINE; MELATONIN; MELATONIN 6 HYDROXYLASE; PHENOBARBITAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG HYDROXYLATION; DRUG METABOLISM; LIVER MICROSOME; MALE; MOLECULAR MODEL; NONHUMAN; RAT;

ANIMALS; BENZOFLAVONES; CHLORZOXAZONE; CYTOCHROME P-450 CYP1A2; ENZYME INHIBITORS; LIVER; MALE; MELATONIN; MICROSOMES, LIVER; MODELS, MOLECULAR; NADP; OXIDATION-REDUCTION; RATS; RATS, WISTAR; THEOPHYLLINE;

EID: 0034764793     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079X.2001.310408.x     Document Type: Article

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