Lithium treatment inhibits protein kinase C translocation in rat brain cortex

Psychopharmacology

Volumn 158, Issue 1, 2001, Pages 80-86

  Wang, H Y ^a   Johnson, G P ^a   Friedman, E ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Frontal cortex; Lithium; Phorbol ester; Protein kinase C; Translocation

Indexed keywords

ANTIBODY; CALCIUM ION; CESIUM; ISOENZYME; LITHIUM CHLORIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PHORBOL MYRISTATE; POTASSIUM ION; PROTEIN KINASE C; RUBIDIUM; SEROTONIN; SEROTONIN RECEPTOR; CALCIMYCIN; CALCIUM; CELL PROTEIN; CELL SURFACE RECEPTOR; LITHIUM; POTASSIUM; PROTEIN ANTIBODY; PSYCHOTROPIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BRAIN SLICE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; CYTOSOL; DIET; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; FRONTAL CORTEX; IMMUNOBLOTTING; LONG TERM EXPOSURE; MALE; NERVE CELL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; ANION EXCHANGE CHROMATOGRAPHY; CALCIUM ANTAGONISM; CONCENTRATION RESPONSE; DRUG INHIBITION; DRUG RESPONSE; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; IMMUNOREACTIVITY; NERVE MEMBRANE; STIMULATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIMANIC AGENTS; CEREBRAL CORTEX; ENZYME INHIBITORS; ISOENZYMES; LITHIUM CHLORIDE; MALE; PROTEIN KINASE C; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTOSOMES;

EID: 0034763841     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100834     Document Type: Article

References (41)

1. The phorbol ester receptor: A phospholipid-regulated protein kinase
2. Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacyl-glycerol levels
3. The Albert Lasker Medical Awards. Inositol triphosphate, calcium, lithium and cell signaling
4. Lithium amplifies agonist-dependent phosphoinositol response in brain and salivary glands
5. Influence of lithium on second messenger accumulation in NG108-15 cells
6. Phorbol ester receptors and protein kinase C in primary neuronal cultures: Development and stimulation of endogenous phosphorylation
7. Effects of chronic lithium treatment on protein kinase C and cyclic AMP dependent protein phosphorylation
8. Changes in inositol lipid metabolism and protein kinase C translocation in nuclei of mitogen stimulated Swiss 3T3 cells
9. 2+ uptake and acetyl phosphatase of skeletal muscle microsomes
10. Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland
11. NMDA induces protein kinase C translocation in guinea pig cerebral synaptoneurosomes
12. The effect of age on brain cortical protein kinase C and its mediation of serotonin release
13. Altered platelet protein kinase C activity in bipolar affective disorder, manic episode
14. Subacute and chronic in vivo lithium treatment inhibits agonist and sodium fluoride-stimulated inositol phosphate production in rat cortex
15. The effects of lithium and other agents on the activity of myo-inositol-phosphatase from bovine brain
16. 1 muscarinic receptors
17. Systemic lithium administration alters rat cerebral cortex phospholipids
18. 2+ influxes
19. 2+, phospholipid-dependent protein kinase associated with plasma membrane
20. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
21. Protein measurement with Folin phenol reagent
22. Phorbol esters block a voltage-sensitive chloride current in hippocampal pyramidal cells
23. Lithium decreases membrane-associated protein kinase C in the hippocampus: Selectivity for the α isozyme
24. Modulation of PKC isozymes and substrates by lithium: The role of myo-inositol
25. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes
26. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
27. Protein kinase C family and nervous function
28. Ion effects on calcium accumulation by cardiac sarcoplasmic reticulum
29. Signal transduction via phosphatidyl-choline cycles
30. Role of cofactors in protein kinase C activation
31. Chronic lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions
32. Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system
33. Localization of subspecies of protein kinase C in the mammalian central nervous system
34. Lithium inhibition of PKC activation and activation-induced serotonin release
35. Central 5-HT receptor-linked protein kinase C translocation: A functional postsynaptic signal transduction system
36. Enhanced protein kinase C activity and translocation in bipolar affective disorder brains
37. Attenuated protein kinase C translocation activity and translocation in Alzheimer's disease brain
38. Increased membrane-associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients
39. Effect of phorbol esters on protein kinase C-ζ
40. Translocation and activation of protein kinase C in striatal neurons in primary culture: Relationship to phorbol dibutyrate actions on the inositol phosphate generating system and neurotransmitter release
41. Translocation of protein kinase C in anterior pituitary tumor cells