Solid-state NMR structure determination of melittin in a lipid environment

Biophysical Journal

Volumn 81, Issue 5, 2001, Pages 2752-2761

  Lam, Y H ^a   Wassall, S R ^b   Morton, C J ^a,d   Smith, R ^c   Separovic, F ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b INDIANA UNIVERSITY   (United States)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MELITTIN; PHOSPHATIDYLCHOLINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ISOTOPE LABELING; LIPID MEMBRANE; MEASUREMENT; MOLECULAR MODEL; PROTEIN LIPID INTERACTION; SOLID STATE; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

EID: 0034763782     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75918-8     Document Type: Article

References (50)

1. Protein-induced membrane disorder: A molecular dynamics study of melittin in a dipalmitoylphosphatidylcholine bilayer
2. Helix geometry in proteins
3. 1H-NMR study in methanol
4. Conformation and aggregation of melittin: Dependence on pH and concentration
5. Molecular dynamics simulation of melittin in a dimyristoylphosphatidylcholine bilayer membrane
6. 203Pb MAS spectra of solid lead nitrate: An accurate, sensitive thermometer for variable-temperature MAS
7. The 9-fluorenylmethoxycarbonyl amino-protecting group
8. Solid-state NMR structural studies of peptides and proteins in membranes
9. The interaction of bee melittin with lipid bilayer membranes
10. The photosynthetic reaction center from the purple bacterium Rhodopseudomonas viridis
11. The actions of melittin on membranes
12. The structure of melittin in lipid bilayer membranes
13. Dynamics of phosphate head groups in biomembranes: Comprehensive analysis using phosphorus-31 nuclear magnetic resonance lineshape and relaxation time measurements
14. 15N-gramicidins A, B, and C and high performance liquid chromatographic purification
15. Torsion angle dynamics for NMR structure calculation with the new program DYANA
16. Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy
17. Structure and interactions of ether- and ester-linked phosphatidylethanolamines
18. Secondary structure and location of a magainin analogue in synthetic phospholipid bilayers
19. Structure, location, and lipid perturbations of melittin at the membrane interface
20. Structure of melittin bound to perdeuterated dodecylphosphocholine micelles as studied by two-dimensional NMR and distance geometry calculations
21. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
22. Gel phase polymorphism in ether-linked dihexadecylphosphatidylcholine bilayers
23. Bilayer interactions of ether- and ester-linked phospholipids: Dihexadecyl- and dipalmitoylphosphatidylcholines
24. Interactions of melittin, a preprotein model, with detergents
25. MOLMOL: A program for display and analysis of macromolecular structures
26. The influence of low amounts of cholesterol on the interdigitated gel phase of hydrated dihexadecylphosphatidylcholine
27. 13C rotational resonance in a transmembrane peptide: A comparison of the fluid and gel phases
28. Theory and simulations of homonuclear spin pair systems in rotating solids
29. Stability of a melittin pore in a lipid bilayer: A molecular dynamics study
30. 13C NMR spectroscopy
31. Vesicle-bound conformation of melittin: Transfered nuclear Overhauser enhancement analysis in the presence of perdeuterated phosphatidylcholine vesicles
32. Orientation change of glycopeptide in lipid bilayer membrane induced by lectin binding
33. Analysis of rotational resonance magnetization exchange curves from crystalline peptides
34. Solid-state NMR approaches for studying membrane protein structure
35. Dimerization of truncated melittin analogues results in cytolytic peptides
36. 31P nuclear magnetic resonance and the head group structure of phospholipids in membranes
37. Amphiphatic helix motifs: Classes and properties
38. 13C carbonyl chemical shift shielding tensor
39. Interaction of a lytic polypeptide, melittin, with lipid membrane systems
40. Structure and orientation of the pore-forming peptide, melittin, in lipid bilayers
41. Conformational change and self association of monomeric melittin
42. The structure of melittin. II. Interpretation of the structure
43. Rotational resonance NMR study of the active site structure in bacteriorhodopsin: Conformation of the Schiff base linkage
44. The sting: Melittin forms channels in lipid bilayers
45. Incorporation of melittin into phosphatidylcholine bilayers: Study of binding and conformational changes
46. Comparison of the conformation and orientation of alamethicin and melittin in lipid membranes
47. The structure of melittin in membranes
48. Calculation of the electric potential in the active site left due to alpha-helix dipoles
49. Structural characterization of the M4 transmembrane domain of the acetylcholine receptor: An NMR study