Bissulfonamides as inhibitors of the dehydroquinate synthetase enzyme AroB and of the Type II dehydroquinase enzyme AroQ

Expert Opinion on Therapeutic Patents

Volumn 11, Issue 11, 2001, Pages 1797-1799

[No Author Info available]

Author keywords

Antibacterial; Antifungal agents; Biosynthesis of amino acids; Bissulfonamides

Indexed keywords

3 DEHYDROQUINATE DEHYDRATASE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; AROMATASE; AROMATIC AMINO ACID; BISSULFONAMIDE DERIVATIVE; ENZYME INHIBITOR; FUNGICIDE; HERBICIDE; LIGNIN; PHENYLALANINE; PROTOCATECHUIC ACID; QUINIC ACID; SHIKIMIC ACID; SULFONAMIDE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ACYLATION; AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; BACTERIUM; BROMINATION; CATABOLISM; ENZYME ACTIVITY; FUNGUS; IC 50; IN VITRO STUDY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NITRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN SYNTHESIS INHIBITION; STAPHYLOCOCCUS AUREUS; VERO CELL;

EID: 0034758820     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.11.11.1797     Document Type: Article

References (6)

1. The prechorismate (shikimate) and quinate pathways in filamentous fungi: Theoretical and practical aspects
2. The Mycobacterium tuberculosis shikimate pathway genes: Evolutionary relationship between biosynthetic and catabolic 3-dehydroquinases
3. Cloning and characterization of the AroA gene from Mycobacterium tuberculosis
4. Carbonic anhydrase inhibitors. Part 29: Interaction of isozymes I, II and IV with benzolamide-like derivatives
5. Carbonic anhydrase inhibitors. Part 57. Quantum chemical QSAR of a group of 1,3,4-thiadiazole and 1,3,4-thiadiazoline disulfonamides with carbonic anhydrase inhibitory properties
6. Carbonic anhydrase inhibitors. Part 61. Quantum Chemical QSAR of a Group of Benzenedisulfonamides