Pioglitazone reduces urinary podocyte excretion in type 2 diabetes patients with microalbuminuria

Metabolism: Clinical and Experimental

Volumn 50, Issue 10, 2001, Pages 1193-1196

  Nakamura, Tsukasa ^a,b,c   Ushiyama, Chifuyu ^a,b,c   Osada, Shiwori ^a,b,c   Hara, Masanori ^a,b,c   Shimada, Noriaki ^a,b,c   Koide, Hikaru ^a,b,c  

^a NATIONAL REHABILITATION CENTER FOR PERSONS WITH DISABILITIES   (Japan)

^b Yoshida Hospital   (Japan)

^c KOTO HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ANTIDIABETIC AGENT; CREATININE; INSULIN; MONOCLONAL ANTIBODY; NITROGEN; PIOGLITAZONE; PLACEBO; PODOCALYXIN; UREA;

ADULT; ARTICLE; CELL COUNT; CELL DAMAGE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; FEMALE; GLOMERULUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INSULIN RESISTANCE; KIDNEY DISEASE; MALE; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PODOCYTE; PRIORITY JOURNAL; URINARY EXCRETION;

EID: 0034758754     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2001.26703     Document Type: Article

References (25)

1. Urinary excretion of podocytes reflects disease activity in children with glomerulonephritis
2. Urinary podocytes for the assessment of disease activity in lupus nephritis
3. The urinary podocyte as a marker for the differential diagnosis of idiopathic focal glomerulosclerosis and minimal-change nephrotic syndrome
4. Urinary excretion of podocytes in patients with diabetic nephropathy
5. Thiazolidinediones: A new class of antidiabetic drugs
6. Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy
7. Diabetes mellitus
8. Long-term effects of angiotensin-converting enzyme inhibition and metabolic control in hypertensive type 2 diabetic patients
9. Increased plasma metalloproteinase-9 concentrations precede development of microalbuminuria in non-insulin-dependent diabetes mellitus
10. The role of podocytes in the development of glomerular sclerosis
11. Glomerular podocytes and adhesive interaction with glomerular basement membrane
12. Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies
13. Podocyte loss and progressive glomerular injury in type II diabetes
14. Podocyte number predicts long-term urinary albumin excretion in Pima Indians with type II diabetes and microalbuminuria
15. Glomerular perms-electivity at the onset of nephropathy in type 2 diabetes mellitus
16. Thiazolidinediones
17. Antihypertensive and vasculo- and renoprotective effects of pioglitazone in genetically obese diabetic rats
18. Comparative effects of pioglitazone, glibenclamide, and voglibose on urinary endothelin-1 and/or urinary albumin excretion in diabetes patients
19. Glomerular epithelial cells synthesize endothelin peptides
20. An orally active ETA/ETB receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis
21. Increased urinary endothelin-1 like immunoreactivity in NIDDM patients with albuminuria
22. Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats
23. Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease
24. Effects of angiotensin-converting enzyme inhibitor, angiotensin II receptor antagonist and calcium antagonist on urinary podocytes in patients with IgA nephropathy
25. Evolution of incipient nephropathy in type 2 diabetes mellitus