Micropolarity and microviscosity of amitriptyline and dextran sulfate/carrageenan-amitriptyline systems: The nature of polyelectrolyte-drug complexes

Journal of Pharmaceutical Sciences

Volumn 90, Issue 10, 2001, Pages 1665-1677

  Hugerth, Andreas M ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Amitriptyline; Carrageenan; Cationic amphiphile; Dextran sulfate; Equilibrium dialysis; Fluorescence; Polyelectrolyte; Polyelectrolyte drug interaction

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; AMITRIPTYLINE; BENZYLIDENE DERIVATIVE; CARRAGEENAN; DEXTRAN SULFATE; POLYELECTROLYTE; PYRENE DERIVATIVE;

ARTICLE; DEPOLARIZATION; DRUG FORMULATION; EQUILIBRIUM DIALYSIS; FLUORESCENCE; VISCOMETRY; VISCOSITY;

EID: 0034758173     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.1117     Document Type: Article

References (47)

1. The effect of charge density and conformation on the polyelectrolyte complex formation between carrageenan and chitosan
2. Some aspects on characterization and properties of charged polysaccharides. An investigation of the system carrageenan/amitriptyline/water with relation to amphiphile adsorption and charge density
3. The physicochemical properties of self-assembled surfactant aggregates as determined by some molecular spectroscopic probe techniques
4. Fluorescence probing in aqueous micellar systems: An overview
5. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems
6. The application of fluorescence techniques to the study of micellar systems
7. Fluorescence studies of hydrophobically modified poly(N-ispropylacrylamides)
8. Fluorescence methods in the study of polymer-surfactant systems
9. Interaction between water-soluble polymers and surfactants: Effect of the polymer hydrophobicity. 1. Hydrophilic polyelectrolytes
10. Large C12TAB micelles formed in complexes with polyvinylsulfate and dextrane sulfate
11. Fluorescence probe studies of aqueous solution interaction between sodium dodecyl sulfate and anionic polyelectrolytes
12. Micellar microfluidities at high pressures
13. Intramolecular excimer formation with diarylalkanes as a microfluidity probe for sodium dodecyl sulphate micelles
14. The application of malonitriles as microviscosity probes in pharmaceutical systems
15. The effect of polyelectrolyte counterion specificity on dextran sulfate-amphiphile interaction in water and aqueous/organic solvent mixtures
16. Dextran sulfate-amphiphile interaction; Effect of polyelectrolyte charge density and amphiphile hydrophobicity
17. Adsorption of charged amphiphiles to oppositely charged polysaccharides-A study of the influence of polysaccharide structure and hydrophobicity of the amphiphile molecule
18. Changes in the polyelectrolyte-amphiphile interaction due to helix-coil transition induced by specific counterions or variations in temperature
19. The effect of hydrophobic character of drugs and helix coil transition of kappa-carrageenan on the polyelectrolyte-drug interaction
20. Polyelectrolyte/amphiphile interaction studied by surface tension measurements
21. Interaction of CnTAB with sodium (carboxymethyl)cellulose: Effect of polyanion linear charge density on bindingisotherms and surfactant aggregation number
22. Monte Carlo simulations of polyelectrolytes at charged micelles. 2. Effects of linear charge density
23. Binding by alkylpyridinium cations by anionic polysaccharides
24. Monte Carlo simulations of polyelectrolytes at charged micelles. 1. Effects of chain flexibility
25. Interaction between water-soluble polymers and surfactants: Effect of the polymer hydrophobicity. 2. Amphiphilic polyelectrolytes (polysoaps)
26. The effect of polyelectrolyte counterion specificity, charge density and conformation on polyelectrolyte-amphiphile interaction. The carrageenan/furcellaranamitriptyline system
27. Surfactant-polyelectrolyte interactions. 2. Effect of multivalent counterions on the binding of dodecyltrimethylammonium ions by sodium dextrane sulfate and sodium poly(styrensulfonate) in aqueous solutions
28. Surfactant-polyelectrolyte interactions. 4. Surfactant chain length dependence of the binding of alkylpyridinium cations to dextrane sulfate
29. Effect of salt on polyelectrolyte-micelle coacervation
30. Critical conditions for the binding of polyelectrolytes to small oppositely charged micelles
31. Interaction between hyaluronan and cationic surfactants
32. Study of surfactant-polyelectrolyte interactions. Binding of dodecyl- and tetradecyltrimethylammonium bromide by some carboxylic polyelectrolytes
33. Surfactant-polyelectrolyte interactions. 1. Binding of dodecyltrimethylammonium ions by sodium dextrane sulfate and sodium poly(styrensulfonate) in aqueous solution in the presence of sodium chloride
34. Study of the solubilization of aromatic hydrocarbons by aqueous micellar solutions
35. Dynamic and static aspects of solubilization of neutral arenes in ionic micellar solutions
36. Interaction of alkyltrimethylammonium surfactants with polyacrylate and poly(styrenesulfonate) in aqueous solution: Phase separation behavior and surfactant aggregation numbers
37. Aggregation of Alkyltrimethylammonium Surfactants in Aqueous Poly(styrenesulfonate) Solutions
38. Alkanediyl-alfa,omega-bis(dimethylammonium bromide). 7. Fluorescence probing studies of micelle micropolarity and microviscosity
39. Microviscosity of aqueous surfactant micelles: Effect of various parameters
40. Location of diphenylhexatriene (DPH) and its derivatives within membranes: Comparison of different fluorescence quenching analysis of membrane depth
41. Characterization of liposomes and other lipid assemblies by multiprobe fluorescence polarization
42. Polarisation de la lumière de fluorescence. Vie moyenne des molécules dans l'etat excité
43. A comparison of the micellar properties of structurally related antidepressant drugs
44. Polymer-surfactant interaction - Recent developments
45. Thermodynamics of kappa-carrageenan-amphiphilic drug interaction as influenced by specific counterions and temperature: A microcalorimetric and viscometric study