Recognition of mitochondrial protein precursor lacking arginine at position -2 by Mitochondrial Processing Peptidase: Processing of bovine cytochrome p450(SCC) precursor

Journal of Biochemistry

Volumn 130, Issue 4, 2001, Pages 497-502

  Kojima, K ^a   Yamasaki, E ^a   Kitada, S ^a   Ogishima, T ^a   Ito, A ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Mitochondrial processing peptidase; Mitochondrial protein precursor; Presequence; Processing; Substrate recognition

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); PEPTIDASE; PROTEIN PRECURSOR;

AMINO ACID SEQUENCE; ARTICLE; CATTLE; ENZYME ACTIVITY; MITOCHONDRION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PROCESSING;

EID: 0034758151     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003012     Document Type: Article

References (24)

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6. Mutational analysis of both subunits from rat mitochondrial processing peptidase
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8. Glycine-rich region of mitochondrial processing peptidase α-subunit is essential for binding and cleavage of the precursor proteins
9. Role of α-subunit of mitochondrial processing peptidase in substrate recognition
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11. Cleavage-site motifs in mitochondrial targeting peptides
12. Arginine residues in the extension peptide are required for cleavage of a precursor by mitochondrial processing peptidase
13. Role of basic amino acids in the cleavage of synthetic peptide substrates by mitochondrial processing peptidase
14. Substrate recognition by mitochondrial processing peptidase toward the malate dehydrogenase precursor
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16. Analysis of elements in the substrate required for processing by mitochondrial processing peptidase
17. Importance of residues carboxyl terminal relative to the cleavage site in substrates of mitochondrial processing peptidase for their specific recognition and cleavage
18. Import and processing of the precursor of cytochrome P-450 (SCC) by bovine adrenal cortex mitochondria
19. Molecular cloning and nucleotide sequence of cDNA for mRNA of mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex
20. Crystal structure of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences
21. Mitochondrial processing peptidase: Multiple-site recognition of precursor proteins
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24. Electrostatic recognition of matrix targeting signal by mitochondrial processing peptidase