Functions of the healthy endothelium

Coronary Artery Disease

Volumn 12, Issue 6, 2001, Pages 485-491

  Kharbanda, Rajesh K ^a   Deanfield, John E ^a,b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b Great Ormond Street Hospital for Children NHS Trust ^*  (United Kingdom)

Author keywords

Endothelium; Nitric oxide; Physiology; Vascular biology; Vascular tone

Indexed keywords

ADENYLATE CYCLASE; ANGIOTENSIN; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; INTEGRIN; KININ; L SELECTIN; NITRIC OXIDE; PADGEM PROTEIN; PROSTACYCLIN; PROSTAGLANDIN; THROMBOXANE A2;

APOPTOSIS; BLOOD CLOTTING; BLOOD VESSEL TONE; CELL ADHESION; CELL FUNCTION; ENZYME ACTIVATION; FIBRINOLYSIS; HOMEOSTASIS; HUMAN; PRIORITY JOURNAL; REVIEW; VASCULAR ENDOTHELIUM;

ENDOTHELIUM, VASCULAR; HUMANS; REFERENCE VALUES;

EID: 0034756752     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-200109000-00007     Document Type: Review

References (54)

1. Differentiation of endothelial cells: Analysis of the constitutive and activated endothelial cell phenotypes
2. Modulation of blood flow and tissue perfusion by endothelium-derived relaxing factor
3. Shear stress dependent regulation of vascular resistance in health and disease: Role of endothelium
4. Endotherapy
5. Control and consequences of endothelial nitric oxide formation
6. Role of the enzyme calmodulin-binding domain in membrane association and phospholipid inhibition of endothelial nitric oxide synthase
7. Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations
8. Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man
9. Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis
10. Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans
11. Role of endothelium in the maintenance of low pulmonary vascular tone in normal children
12. Cellular and molecular mechanisms of endothelial cell dysfunction
13. Tetrahydrobiopterin and endothelial nitric oxide synthase activity
14. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
15. Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
16. Oxygen radical-nitric oxide reactions in vascular diseases
17. Endothelial function in hypertension: The role of superoxide anion
18. Effect of copper - Zinc superoxide dismutase on endothelium-dependent vasodilation in patients with essential hypertension
19. Vascular extracellular superoxide dismutase activity in patients with coronary artery disease: Relation to endothelium-dependent vasodilation
20. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
21. International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
22. Continuous release of vasodilator prostanoids contributes to regulation of resting forearm blood flow in humans
23. Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation
24. Aspirin improves endothelial dysfunction in atherosclerosis
25. Bradykinin-induced vasodilation of human forearm resistance vessels is primarily mediated by endothelium-dependent hyperpolarization
26. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans
27. Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
28. Pathophysiology of endothelin in the cardiovascular system
29. Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension
30. Acute endothelin-A receptor antagonism prevents normal reduction of myocardial ischemia on repeated balloon inflations during angioplasty
31. The alternative: EDHF
32. Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone
33. Nitric oxide and prostacyclin modulate the alterations in cardiac action potential duration mediated by platelets during ischaemia
34. Contrasting inotropic effects of endogenous endothelin in the normal and failing human heart: Studies with an intracoronary ET(A) receptor antagonist
35. Role of endothelium-derived nitric oxide in the regulation of cardiac oxygen metabolism: Implications in health and disease
36. The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusion
37. Nitric oxide protects against leukocyte - Endothelium interactions in the early stages of hypercholesterolemia
38. Leukocyte - Endothelial cell adhesion: Avenues for therapeutic intervention
39. Leukocyte - Endothelial cell interactions in nitric oxide synthase-deficient mice
40. Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction
41. Plasma concentration of soluble vascular cell adhesion molecule-1 and subsequent cardiovascular risk
42. Inhibition of fibrinogen binding to human platelets by S-nitroso-N-acetylcysteine
43. Effects of nitric oxide/EDRF on platelet surface glycoproteins
44. Effect of atherosclerosis on endothelium-dependent inhibition of platelet activation in humans
45. Blood coagulation
46. Coagulation and bleeding disorders: Review and update
47. Antithrombotic and prothrombotic activities of the vascular endothelium
48. Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease
49. Regulation of local tissue-type plasminogen activator release byendothelium-dependent and endothelium-independent agonists in human vasculature
50. Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway [in process citation]
51. Fibrinolytic actions of intra-arterial angiotensin II and bradykinin in vivo in man
52. High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infarction in both men and women: Evidence for the fibrinolytic system as an independent primary risk factor
53. Association of blood pressure with fibrinolytic potential in the Framingham offspring population
54. Endothelial apoptosis: Could it have a role in the pathogenesis and treatment of disease?