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Volumn 41, Issue 2, 1997, Pages 199-212

Mechanisms of normal and abnormal neurulation: Evidence from embryo culture studies

Author keywords

diabetes; folate; mutant genes; neural tube defects; teratogen

Indexed keywords

ARACHIDONIC ACID; FOLIC ACID; METHIONINE; VALPROIC ACID;

EID: 0030991904     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (159)
  • 1
    • 0028169992 scopus 로고
    • HNF-3b is essential for node and notochord formation in mouse development
    • ANG, S-L and ROSSANT, J. (1994). HNF-3b is essential for node and notochord formation in mouse development Cell 78 561-574
    • (1994) Cell , vol.78 , pp. 561-574
    • Ang, S.-L.1    Rossant, J.2
  • 2
    • 84981841769 scopus 로고
    • Analysis of the developmental effects of a lethal mutation in the house mouse
    • AUERBACH, R. (1954). Analysis of the developmental effects of a lethal mutation in the house mouse J Exp. Zool 127: 305-329.
    • (1954) J Exp. Zool , vol.127 , pp. 305-329
    • Auerbach, R.1
  • 3
    • 0027752316 scopus 로고
    • Antisense attenuation of Wnt-1 and Wnt-3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis
    • AUGUSTINE, K , LIU, E T. and SADLER, T.W (1993). Antisense attenuation of Wnt-1 and Wnt-3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis Dev. Genet 14: 500-520.
    • (1993) Dev. Genet , vol.14 , pp. 500-520
    • Augustine, K.1    Liu, E.T.2    Sadler, T.W.3
  • 4
    • 0029145768 scopus 로고
    • Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development
    • AUGUSTINE, KA, LIU, E.T. and SADLER, T W (1995). Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development Teratology 51. 300-310
    • (1995) Teratology , vol.51 , pp. 300-310
    • Augustine, K.A.1    Liu, E.T.2    Sadler, T.W.3
  • 5
    • 0020055783 scopus 로고
    • Differences in the toxicity and teratogenicity of cytochalasins D and E in various mouse strains
    • AUSTIN, W.L. WIND, M and BROWN, K.S. (1982). Differences in the toxicity and teratogenicity of cytochalasins D and E in various mouse strains Teratology 25: 11-18
    • (1982) Teratology , vol.25 , pp. 11-18
    • Austin, W.L.1    Wind, M.2    Brown, K.S.3
  • 6
    • 0025869919 scopus 로고
    • Effects of nitrous oxide on day 9 rat embryos grown in culture
    • BADEN, J.M and FUJINAGA, M (1991). Effects of nitrous oxide on day 9 rat embryos grown in culture Br. J. Anaesth 66 500-503.
    • (1991) Br. J. Anaesth , vol.66 , pp. 500-503
    • Baden, J.M.1    Fujinaga, M.2
  • 7
    • 0025013924 scopus 로고
    • Myo-inositol and prostaglandins reverse the glucose inhibition of neural tube fusion in cultured mouse embryos
    • BAKER, L., PIDDINGTON, R., GOLDMAN, A., EGLER, J and MOEHRING, J. (1990). Myo-inositol and prostaglandins reverse the glucose inhibition of neural tube fusion in cultured mouse embryos. Diabetologia 33: 593-596.
    • (1990) Diabetologia , vol.33 , pp. 593-596
    • Baker, L.1    Piddington, R.2    Goldman, A.3    Egler, J.4    Moehring, J.5
  • 8
    • 0014083248 scopus 로고
    • Cytoplasmic filaments and morphogenetic movement in the amphibian neural tube
    • BAKER, P.C and SCHROEDER, T E (1967) Cytoplasmic filaments and morphogenetic movement in the amphibian neural tube. Dev Biol 15 432-450
    • (1967) Dev Biol , vol.15 , pp. 432-450
    • Baker, P.C.1    Schroeder, T.E.2
  • 9
    • 0019604166 scopus 로고
    • An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo
    • BEDDINGTON, R S.P (1981). An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo J Embryol. Exp Morphol 64. 87-104
    • (1981) J Embryol. Exp Morphol , vol.64 , pp. 87-104
    • Beddington, R.S.P.1
  • 10
    • 0020002205 scopus 로고
    • An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse
    • BEDDINGTON, R S P (1982) An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse. J. Embryol Exp. Morphol 69: 265-285
    • (1982) J. Embryol Exp. Morphol , vol.69 , pp. 265-285
    • Beddington, R.S.P.1
  • 11
    • 0026698879 scopus 로고
    • Effects of antibodies against N-cadherin and N-CAM on the cranial neural crest and neural tube
    • BRONNER-FRASER, M., WOLF, J.J and MURRAY, B.A. (1992). Effects of antibodies against N-cadherin and N-CAM on the cranial neural crest and neural tube. Dev Biol 753: 291-301.
    • (1992) Dev Biol , vol.753 , pp. 291-301
    • Bronner-Fraser, M.1    Wolf, J.J.2    Murray, B.A.3
  • 12
    • 0025947203 scopus 로고
    • Curvature of the caudal region is responsible for failure of neural tube closure in the curly tail (ct) mouse embryo
    • BROOK, F.A., SHUM, A S.W , VAN STRAATEN, H.W M. and COPP, A.J. (1991). Curvature of the caudal region is responsible for failure of neural tube closure in the curly tail (ct) mouse embryo. Development 113. 671-678
    • (1991) Development , vol.113 , pp. 671-678
    • Brook, F.A.1    Shum, A.S.W.2    Van Straaten, H.W.M.3    Copp, A.J.4
  • 13
    • 0020661447 scopus 로고
    • Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryos in culture
    • BRUCKNER, A , LEE, Y.J., O'SHEA, K.S. and HENNEBERRY, R.C. (1983). Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryos in culture Teratology 27: 29-42.
    • (1983) Teratology , vol.27 , pp. 29-42
    • Bruckner, A.1    Lee, Y.J.2    O'Shea, K.S.3    Henneberry, R.C.4
  • 14
    • 0028216161 scopus 로고
    • Diabetic teratogenesis: In vitro evidence for a muitifactorial etiology with little contribution from glucose per se
    • BUCHANAN, T.A., DENNO, K.M., SIPOS, G F. and SADLER, T.W. (1994). Diabetic teratogenesis: in vitro evidence for a muitifactorial etiology with little contribution from glucose per se. Diabetes 43: 656-660.
    • (1994) Diabetes , vol.43 , pp. 656-660
    • Buchanan, T.A.1    Denno, K.M.2    Sipos, G.F.3    Sadler, T.W.4
  • 15
    • 0024564718 scopus 로고
    • The new mouse genetics - Altering the genome by gene targeting
    • CAPECCHI, M R (1989). The new mouse genetics - altering the genome by gene targeting. Trends Genet. 5: 70
    • (1989) Trends Genet. , vol.5 , pp. 70
    • Capecchi, M.R.1
  • 16
    • 0028933142 scopus 로고
    • Twistis required in head mesenchyme for cranial neural tube morphogenesis
    • CHEN, Z-F and BEHRINGER, R.R. (1995). twistis required in head mesenchyme for cranial neural tube morphogenesis Genes Dev. 9: 686-699.
    • (1995) Genes Dev. , vol.9 , pp. 686-699
    • Chen, Z.-F.1    Behringer, R.R.2
  • 17
    • 0018536679 scopus 로고
    • Nutrient requirements of rat embryos undergoing organogenesis in vitro
    • COCKROFT, D.L. (1979). Nutrient requirements of rat embryos undergoing organogenesis in vitro. J. Reprod Fertil. 57. 505-510
    • (1979) J. Reprod Fertil. , vol.57 , pp. 505-510
    • Cockroft, D.L.1
  • 18
    • 0021213517 scopus 로고
    • Abnormalities induced in cultured rat embryos by hyperglycaemia
    • COCKROFT, D.L. (1984). Abnormalities induced in cultured rat embryos by hyperglycaemia. Br. J. Exp Pathol. 65: 625-636.
    • (1984) Br. J. Exp Pathol. , vol.65 , pp. 625-636
    • Cockroft, D.L.1
  • 19
    • 0023681596 scopus 로고
    • Changes with gestational age in the nutritional requirements of postimplantation rat embryos in culture
    • COCKROFT, D.L. (1988) Changes with gestational age in the nutritional requirements of postimplantation rat embryos in culture. Teratology 38: 281-290.
    • (1988) Teratology , vol.38 , pp. 281-290
    • Cockroft, D.L.1
  • 20
    • 0017712779 scopus 로고
    • Teratogenic effects of excess glucose on headfold rat embryos in culture
    • COCKROFT, D.L and COPPOLA, P.T. (1977). Teratogenic effects of excess glucose on headfold rat embryos in culture Teratology 16. 141-146.
    • (1977) Teratology , vol.16 , pp. 141-146
    • Cockroft, D.L.1    Coppola, P.T.2
  • 21
    • 0026513724 scopus 로고
    • Inositol deficiency increases the susceptibility to neural tube defects of genetically predisposed (curly tail) mouse embryos in vitro
    • COCKROFT, D L., BROOK, F A. and COPP, A J (1992) Inositol deficiency increases the susceptibility to neural tube defects of genetically predisposed (curly tail) mouse embryos in vitro. Teratology 45. 223-232.
    • (1992) Teratology , vol.45 , pp. 223-232
    • Cockroft, D.L.1    Brook, F.A.2    Copp, A.J.3
  • 22
    • 0024852401 scopus 로고
    • Whole rat embryos require methionine for neural tube closure when cultured on cow serum
    • COELHO, C.N.D , WEBER, J.A., KLEIN, N.W., DANIELS, W.G. and HOAGLAND, T.A. (1989). Whole rat embryos require methionine for neural tube closure when cultured on cow serum. J. Nutr. 119: 1716-1725.
    • (1989) J. Nutr. , vol.119 , pp. 1716-1725
    • Coelho, C.N.D.1    Weber, J.A.2    Klein, N.W.3    Daniels, W.G.4    Hoagland, T.A.5
  • 23
    • 0028989016 scopus 로고
    • Notch1 is required for the coordinate segmentation of somites
    • CONLON, R.A., REAUME, A G. and ROSSANT, J (1995) Notch1 is required for the coordinate segmentation of somites. Development 121: 1533-1545
    • (1995) Development , vol.121 , pp. 1533-1545
    • Conlon, R.A.1    Reaume, A.G.2    Rossant, J.3
  • 24
    • 8244238120 scopus 로고
    • Teratology and experimental embryology: The pathogenesis of neural tube defects
    • (Ed. J.B. Warshaw). Elsevier Biomedical, New York
    • COPP, A J. (1983) Teratology and experimental embryology: the pathogenesis of neural tube defects In The Biological Basis of Reproductive and Developmental Medicine (Ed. J.B. Warshaw). Elsevier Biomedical, New York, pp. 155-178.
    • (1983) The Biological Basis of Reproductive and Developmental Medicine , pp. 155-178
    • Copp, A.J.1
  • 25
    • 0024259837 scopus 로고
    • Glycosaminoglycans vary in accumulation along the neuraxis during spinal neurulation in the mouse embryo
    • COPP, A.J. and BERNFIELD, M. (1988a). Glycosaminoglycans vary in accumulation along the neuraxis during spinal neurulation in the mouse embryo. Dev. Biol. 130: 573-582.
    • (1988) Dev. Biol. , vol.130 , pp. 573-582
    • Copp, A.J.1    Bernfield, M.2
  • 26
    • 0024273030 scopus 로고
    • Accumulation of basement membrane-associated hyaluronate is reduced in the posterior neuropore region of mutant (curly tail) mouse embryos developing spinal neural tube defects
    • COPP, A J and BERNFIELD. M. (1988b). Accumulation of basement membrane-associated hyaluronate is reduced in the posterior neuropore region of mutant (curly tail) mouse embryos developing spinal neural tube defects. Dev Biol. 130: 583-590.
    • (1988) Dev Biol. , vol.130 , pp. 583-590
    • Copp, A.J.1    Bernfield, M.2
  • 27
    • 0028003811 scopus 로고
    • Etiology and pathogenesis of human neural tube defects: Insights from mouse models
    • COPP, A J and BERNFIELD, M. (1994) Etiology and pathogenesis of human neural tube defects: insights from mouse models. Curr Opin. Pediatr 6: 624-631.
    • (1994) Curr Opin. Pediatr , vol.6 , pp. 624-631
    • Copp, A.J.1    Bernfield, M.2
  • 28
    • 0023709064 scopus 로고
    • A cell-type-specific abnormality of cell proliferation in mutant (curly tail) mouse embryos developing spinal neural tube defects
    • COPP, A.J., BROOK, F A. and ROBERTS, H.J. (1988a). A cell-type-specific abnormality of cell proliferation in mutant (curly tail) mouse embryos developing spinal neural tube defects Development 104 285-295
    • (1988) Development , vol.104 , pp. 285-295
    • Copp, A.J.1    Brook, F.A.2    Roberts, H.J.3
  • 29
    • 0028040705 scopus 로고
    • Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse use of microsatellite DNA markers to identify embryonic genotype
    • COPP, A J., CHECIU, I. and HENSON, J N (1994). Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse use of microsatellite DNA markers to identify embryonic genotype Dev Biol. 165. 20-29
    • (1994) Dev Biol. , vol.165 , pp. 20-29
    • Copp, A.J.1    Checiu, I.2    Henson, J.N.3
  • 30
    • 0023736270 scopus 로고
    • Prevention of spinal neural tube defects in the mouse embryo by growth retardation during neurulation
    • COPP, A.J , CROLLA, J.A. and BROOK, F.A (1988b). Prevention of spinal neural tube defects in the mouse embryo by growth retardation during neurulation. Development 104 297-303.
    • (1988) Development , vol.104 , pp. 297-303
    • Copp, A.J.1    Crolla, J.A.2    Brook, F.A.3
  • 31
    • 0026674282 scopus 로고
    • Exogenous transferrin is taken up and localized by the neurulation-stage mouse embryo in vitro
    • COPP, A J., ESTIBEIRO, J.P., BROOK, F.A. and DOWNS, K.M. (1992). Exogenous transferrin is taken up and localized by the neurulation-stage mouse embryo in vitro. Dev. Biol. 153: 312-323.
    • (1992) Dev. Biol. , vol.153 , pp. 312-323
    • Copp, A.J.1    Estibeiro, J.P.2    Brook, F.A.3    Downs, K.M.4
  • 32
    • 0022559164 scopus 로고
    • Chimaerism of primordial germ cells in the early postimplantation mouse embryo following microsurgical grafting of posterior primitive streak cells in vitro
    • COPP, A J , ROBERTS, H.M and POLANI, P E. (1986). Chimaerism of primordial germ cells in the early postimplantation mouse embryo following microsurgical grafting of posterior primitive streak cells in vitro J. Embryol. Exp Morphol 95: 95-115.
    • (1986) J. Embryol. Exp Morphol , vol.95 , pp. 95-115
    • Copp, A.J.1    Roberts, H.M.2    Polani, P.E.3
  • 33
    • 0027717655 scopus 로고
    • Analysis of neural tube defects in a mouse mutant using whole embryo culture
    • COPP, A J , SHUM, A S W. and BROOK, F.A (1993). Analysis of neural tube defects in a mouse mutant using whole embryo culture. Toxicol in Vitro 7: 679-684.
    • (1993) Toxicol in Vitro , vol.7 , pp. 679-684
    • Copp, A.J.1    Shum, A.S.W.2    Brook, F.A.3
  • 34
    • 0019848843 scopus 로고
    • Cranial glycosaminoglycans in early embryos of the Loop-tail (Lp) mutant mouse
    • COPP, S.N. and WILSON, D.B. (1981). Cranial glycosaminoglycans in early embryos of the Loop-tail (Lp) mutant mouse. J. Craniofac. Genet. Dev. Biol. 1. 253-260.
    • (1981) J. Craniofac. Genet. Dev. Biol. , vol.1 , pp. 253-260
    • Copp, S.N.1    Wilson, D.B.2
  • 36
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
    • CZEIZEL, A.E. and DUDÁS, I.(1992) Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation N. Engl J Med. 327 1832-1835.
    • (1992) N. Engl J Med. , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudás, I.2
  • 38
    • 0025296726 scopus 로고
    • Marked accumulation of valproic acid in embryonic neuroepithelium of the mouse during early organogenesis
    • DENCKER, L , NAU, H. and D'ARGY, R. (1990). Marked accumulation of valproic acid in embryonic neuroepithelium of the mouse during early organogenesis. Teratology 41: 699-706.
    • (1990) Teratology , vol.41 , pp. 699-706
    • Dencker, L.1    Nau, H.2    D'Argy, R.3
  • 39
    • 0028598814 scopus 로고
    • Munne FGFR-1 is required for early postimplantation growth and axial organization
    • DENG, C-X., WYNSHAW-BORIS, A., SHEN, M.M., DAUGHERTY, C., ORNITZ, D.M. and LEDER, P. (1994). Munne FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8. 3045-3057.
    • (1994) Genes Dev. , vol.8 , pp. 3045-3057
    • Deng, C.-X.1    Wynshaw-Boris, A.2    Shen, M.M.3    Daugherty, C.4    Ornitz, D.M.5    Leder, P.6
  • 40
    • 0025275826 scopus 로고
    • The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos
    • DETRICK, R.J., DICKEY, D. and KINTNER, C.R. (1990) The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos. Neuron 4. 493-506
    • (1990) Neuron , vol.4 , pp. 493-506
    • Detrick, R.J.1    Dickey, D.2    Kintner, C.R.3
  • 41
    • 0026669144 scopus 로고
    • Spina bifida aperta induced by valproic acid and by all-frans-retinoic acid in the mouse: Distinct differences in morphology and periods of sensitivity
    • EHLERS, K , STÜRJE, H., MERKER, H-J. and NAU, H. (1992a). Spina bifida aperta induced by valproic acid and by all-frans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity. Teratology 46. 117-130
    • (1992) Teratology , vol.46 , pp. 117-130
    • Ehlers, K.1    Stürje, H.2    Merker, H.-J.3    Nau, H.4
  • 42
    • 0026556607 scopus 로고
    • Valproic acid-induced spina bifida: A mouse model
    • EHLERS, K , STÜRJE, H., MERKER, H-J. and NAU, H. (1992b). Valproic acid-induced spina bifida: a mouse model. Teratology 45: 145-154.
    • (1992) Teratology , vol.45 , pp. 145-154
    • Ehlers, K.1    Stürje, H.2    Merker, H.-J.3    Nau, H.4
  • 43
    • 0027394254 scopus 로고
    • Diabetes and embryonic malformations: Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos
    • ERIKSSON, U.J. and BORG, L.A H. (1993). Diabetes and embryonic malformations: role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos. Diabetes 42: 411-419.
    • (1993) Diabetes , vol.42 , pp. 411-419
    • Eriksson, U.J.1    Borg, L.A.H.2
  • 44
    • 0026513723 scopus 로고
    • Maternal methionine supplementation promotes the remediation of axial defects in Axd mouse neural tube mutants
    • ESSIEN, F.B. (1992). Maternal methionine supplementation promotes the remediation of axial defects in Axd mouse neural tube mutants. Teratology 45: 205-212.
    • (1992) Teratology , vol.45 , pp. 205-212
    • Essien, F.B.1
  • 45
    • 0027326435 scopus 로고
    • Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells
    • FERNANDEZ, J.L.R , GEIGER, B., SALOMON, D. and BEN-ZE'EV, A. (1993). Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells. J. Cell Biol 122: 1285-1294.
    • (1993) J. Cell Biol , vol.122 , pp. 1285-1294
    • Fernandez, J.L.R.1    Geiger, B.2    Salomon, D.3    Ben-Ze'ev, A.4
  • 46
    • 0020647549 scopus 로고
    • Evidence that protein ingested by the rat visceral yolk sac yields amino acids for synthesis of embryonic protein
    • FREEMAN, S.J. and LLOYD, J B (1983). Evidence that protein ingested by the rat visceral yolk sac yields amino acids for synthesis of embryonic protein. J. Embryol Exp Morphol. 73: 307-315.
    • (1983) J. Embryol Exp Morphol. , vol.73 , pp. 307-315
    • Freeman, S.J.1    Lloyd, J.B.2
  • 47
    • 0028302639 scopus 로고
    • Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture
    • FUJINAGA, M. and BADEN, J.M (1994) Methionine prevents nitrous oxide-induced teratogenicity in rat embryos grown in culture. Anesthesiology 81: 184-189.
    • (1994) Anesthesiology , vol.81 , pp. 184-189
    • Fujinaga, M.1    Baden, J.M.2
  • 48
    • 0018651552 scopus 로고
    • Investigation of the fate of 4.5 day postcoitum mouse inner cell mass cells by blastocyst injection
    • GARDNER, R.L. and ROSSANT. J. (1979). Investigation of the fate of 4.5 day postcoitum mouse inner cell mass cells by blastocyst injection. J Embryoi. Exp. Morphol 52: 141-152.
    • (1979) J Embryoi. Exp. Morphol , vol.52 , pp. 141-152
    • Gardner, R.L.1    Rossant, J.2
  • 49
    • 0027461863 scopus 로고
    • Intermittent pattern of neural tube closure in two strains of mice
    • GOLDEN, J.A and CHERNOFF, G.F. (1993). Intermittent pattern of neural tube closure in two strains of mice. Teratology 47: 73-80
    • (1993) Teratology , vol.47 , pp. 73-80
    • Golden, J.A.1    Chernoff, G.F.2
  • 50
    • 0028969815 scopus 로고
    • Multiple sites of anterior neural tube closure in humans. evidence from antenor neural tube defects (anencephaly)
    • GOLDEN, J A and CHERNOFF, G.F. (1995). Multiple sites of anterior neural tube closure in humans. evidence from antenor neural tube defects (anencephaly). Pediatrics 95. 506-510.
    • (1995) Pediatrics , vol.95 , pp. 506-510
    • Golden, J.A.1    Chernoff, G.F.2
  • 51
    • 0344170888 scopus 로고
    • Hyperglycemia-induced teratogenesis is mediated by a functional deficiency of arachidonic acid
    • GOLDMAN, A.S , BAKER, L., PIDDINGTON, R., MARX, B, HEROLD, R and EGLER, J. (1985). Hyperglycemia-induced teratogenesis is mediated by a functional deficiency of arachidonic acid. Proc. Natl. Acad. Sci. USA 82. 8227-8231.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8227-8231
    • Goldman, A.S.1    Baker, L.2    Piddington, R.3    Marx, B.4    Herold, R.5    Egler, J.6
  • 52
    • 0022339117 scopus 로고
    • A review of the theories of vertebrate neurulation and their relationship to the mechanics of neural tube birth defects
    • GORDON, R (1985) A review of the theories of vertebrate neurulation and their relationship to the mechanics of neural tube birth defects. J Embryol. Exp. Morphol 89 (Suppl): 229-255.
    • (1985) J Embryol. Exp. Morphol , vol.89 , Issue.SUPPL. , pp. 229-255
    • Gordon, R.1
  • 53
    • 0031033593 scopus 로고    scopus 로고
    • Inositol prevents folate-resistant neural tube defects in the mouse
    • GREENE, N.D E and COPP, A.J. (1997). Inositol prevents folate-resistant neural tube defects in the mouse Nature Med 3: 60-66.
    • (1997) Nature Med , vol.3 , pp. 60-66
    • Greene, N.D.E.1    Copp, A.J.2
  • 54
    • 0029059790 scopus 로고
    • Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
    • HANKS, M , WURST, W., ANSON-CARTWRIGHT, L , AUERBACH, A.B. and JOYNER, A.L. (1995). Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269 679-682.
    • (1995) Science , vol.269 , pp. 679-682
    • Hanks, M.1    Wurst, W.2    Anson-Cartwright, L.3    Auerbach, A.B.4    Joyner, A.L.5
  • 55
    • 0025801759 scopus 로고
    • Lack of attenuation of valproic acid-induced effects by folinic acid in rat embryos in vitro
    • HANSEN, D.K. and GRAFTON, T.F (1991) Lack of attenuation of valproic acid-induced effects by folinic acid in rat embryos in vitro. Teratology 43 575-582.
    • (1991) Teratology , vol.43 , pp. 575-582
    • Hansen, D.K.1    Grafton, T.F.2
  • 56
    • 0028877316 scopus 로고
    • Lack of attenuation of valproic acid-induced embryotoxicity by compounds involved in one-carbon transfer reactions
    • HANSEN, D.K., DIAL, S.L. and GRAFTON, T F. (1995) Lack of attenuation of valproic acid-induced embryotoxicity by compounds involved in one-carbon transfer reactions. Toxicol. in Vitro 9. 615-621.
    • (1995) Toxicol. in Vitro , vol.9 , pp. 615-621
    • Hansen, D.K.1    Dial, S.L.2    Grafton, T.F.3
  • 57
    • 0025166343 scopus 로고
    • Effect of lithium carbonate on mouse and rat embryos in vitro
    • HANSEN, D.K., WALKER, R.C. and GRAFTON, T F. (1990). Effect of lithium carbonate on mouse and rat embryos in vitro. Teratology 41: 155-160.
    • (1990) Teratology , vol.41 , pp. 155-160
    • Hansen, D.K.1    Walker, R.C.2    Grafton, T.F.3
  • 58
  • 59
    • 0028972499 scopus 로고
    • Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
    • HERMISTON, M.L and GORDON, J.I (1995). Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270. 1203-1207.
    • (1995) Science , vol.270 , pp. 1203-1207
    • Hermiston, M.L.1    Gordon, J.I.2
  • 60
    • 0022978398 scopus 로고
    • Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: Failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis
    • HOD, M , STAR, S , PASSONNEAU, J V , UNTERMAN, T G and FREINKEL, N. (1986). Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis. Biochem. Biophys. Res. Commun. 140: 974-980.
    • (1986) Biochem. Biophys. Res. Commun. , vol.140 , pp. 974-980
    • Hod, M.1    Star, S.2    Passonneau, J.V.3    Unterman, T.G.4    Freinkel, N.5
  • 61
    • 0028961719 scopus 로고
    • Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene
    • HOMANICS, G.E., MAEDA, N , TRABER, M.G., KAYDEN, H.J., DEHART, D.B. and SULIK, K.K. (1995). Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene Teratology 51: 1-10.
    • (1995) Teratology , vol.51 , pp. 1-10
    • Homanics, G.E.1    Maeda, N.2    Traber, M.G.3    Kayden, H.J.4    Dehart, D.B.5    Sulik, K.K.6
  • 62
    • 0029766538 scopus 로고    scopus 로고
    • Transferrin and its receptor in the development of genetically-determined neural tube defects in the mouse embryo
    • HOYLE, C , HENDERSON, D J., MATTHEWS, D.J. and COPP, A J. (1996) Transferrin and its receptor in the development of genetically-determined neural tube defects in the mouse embryo. Dev. Dynamics 207: 36-46.
    • (1996) Dev. Dynamics , vol.207 , pp. 36-46
    • Hoyle, C.1    Henderson, D.J.2    Matthews, D.J.3    Copp, A.J.4
  • 63
    • 0027478216 scopus 로고
    • J mutation contains an intragenic deletion of the Gli3 gene
    • J mutation contains an intragenic deletion of the Gli3 gene. Nature Genet. 3 241-246
    • (1993) Nature Genet. , vol.3 , pp. 241-246
    • Hui, C.1    Joyner, A.L.2
  • 64
    • 0023201165 scopus 로고
    • D-(-)-beta-hydroxybutyrate-induced effects on mouse embryos in vitro
    • HUNTER, E S. and SADLER, T.W (1987). D-(-)-beta-hydroxybutyrate-induced effects on mouse embryos in vitro. Teratology 36: 259-264.
    • (1987) Teratology , vol.36 , pp. 259-264
    • Hunter, E.S.1    Sadler, T.W.2
  • 65
    • 0026500454 scopus 로고
    • The role of the visceral yolk sac in hyperglycemia-induced embryopathies in mouse embryos in vitro
    • HUNTER, E.S. and SADLER, T.W. (1992). The role of the visceral yolk sac in hyperglycemia-induced embryopathies in mouse embryos in vitro Teratology 45: 195-203
    • (1992) Teratology , vol.45 , pp. 195-203
    • Hunter, E.S.1    Sadler, T.W.2
  • 66
    • 0025811063 scopus 로고
    • Altered visceral yolk sac function produced by a low-molecular-weight somatomedin inhibitor
    • HUNTER, E.S., PHILLIPS, L.S., GOLDSTEIN, S. and SADLER, T.W (1991). Altered visceral yolk sac function produced by a low-molecular-weight somatomedin inhibitor. Teratology 43: 331-340
    • (1991) Teratology , vol.43 , pp. 331-340
    • Hunter, E.S.1    Phillips, L.S.2    Goldstein, S.3    Sadler, T.W.4
  • 67
    • 0023235911 scopus 로고
    • A potential mechanism of DL-beta-hydroxybutyrate-induced malformations in mouse embryos
    • HUNTER, E.S., SADLER, T.W. and WYNN, R.E. (1987) A potential mechanism of DL-beta-hydroxybutyrate-induced malformations in mouse embryos. Am. J. Physiol. 253: E72-E80.
    • (1987) Am. J. Physiol. , vol.253
    • Hunter, E.S.1    Sadler, T.W.2    Wynn, R.E.3
  • 68
    • 0027289232 scopus 로고
    • Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice
    • IMAMOTO, A and SORIANO, P (1993) Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell 73 1117-1124
    • (1993) Cell , vol.73 , pp. 1117-1124
    • Imamoto, A.1    Soriano, P.2
  • 69
    • 0029595271 scopus 로고
    • Targeted disruption of mammalian hairy and Enhancer of splithomolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
    • ISHIBASHI, M., ANG, S-L., SHIOTA, K , NAKANISHI, S., KAGEYAMA, R and GUILLEMOT, F. (1995). Targeted disruption of mammalian hairy and Enhancer of splithomolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 9: 3136-3148.
    • (1995) Genes Dev. , vol.9 , pp. 3136-3148
    • Ishibashi, M.1    Ang, S.-L.2    Shiota, K.3    Nakanishi, S.4    Kageyama, R.5    Guillemot, F.6
  • 71
    • 0016164151 scopus 로고
    • The mechanisms of neural tube formation
    • KARFUNKEL, P. (1974). The mechanisms of neural tube formation. Int. Rev Cytol. 38: 245-271.
    • (1974) Int. Rev Cytol. , vol.38 , pp. 245-271
    • Karfunkel, P.1
  • 72
    • 0014247312 scopus 로고
    • Lengthening of the generation cycle during embryonic differentiation of the mouse neural tube
    • KAUFFMAN, S.L. (1968). Lengthening of the generation cycle during embryonic differentiation of the mouse neural tube Exp Cell Res 49 420-424
    • (1968) Exp Cell Res , vol.49 , pp. 420-424
    • Kauffman, S.L.1
  • 73
    • 0023775930 scopus 로고
    • Arachidonic acid reversal of phenytoin-induced neural tube and craniofacial defects in vitro in mice
    • KAY, E D., GOLDMAN, A S and DANIEL, J.C. (1988). Arachidonic acid reversal of phenytoin-induced neural tube and craniofacial defects in vitro in mice. J. Craniofac. Genet. Dev. Biol. 8: 179-186
    • (1988) J. Craniofac. Genet. Dev. Biol. , vol.8 , pp. 179-186
    • Kay, E.D.1    Goldman, A.S.2    Daniel, J.C.3
  • 75
    • 0026619863 scopus 로고
    • Effect of lithium on rat embryos in culture: Growth, development, compartmental distribution and lack of a protective effect of inositol
    • KLUG, S., COLLINS, M., NAGAO, T., MERKER, H-J. and NEUBERT, D. (1992). Effect of lithium on rat embryos in culture: growth, development, compartmental distribution and lack of a protective effect of inositol Arch Toxicol. 66: 719-728.
    • (1992) Arch Toxicol. , vol.66 , pp. 719-728
    • Klug, S.1    Collins, M.2    Nagao, T.3    Merker, H.-J.4    Neubert, D.5
  • 77
    • 0023627388 scopus 로고
    • Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse
    • LAWSON, K A and PEDERSEN, R A (1987). Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse. Development 101: 627-652.
    • (1987) Development , vol.101 , pp. 627-652
    • Lawson, K.A.1    Pedersen, R.A.2
  • 78
    • 0022921031 scopus 로고
    • Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer
    • LAWSON, K A., MENESES, J.J. and PEDERSEN, R A (1986). Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer Dev Biol 115: 325-339.
    • (1986) Dev Biol , vol.115 , pp. 325-339
    • Lawson, K.A.1    Meneses, J.J.2    Pedersen, R.A.3
  • 79
    • 0025942116 scopus 로고
    • Clonal analysis of epiblast fate during germ layer formation in the mouse embryo
    • LAWSON, K.A., MENESES, J.J and PEDERSEN, R A (1991) Clonal analysis of epiblast fate during germ layer formation in the mouse embryo Development 113: 891-911.
    • (1991) Development , vol.113 , pp. 891-911
    • Lawson, K.A.1    Meneses, J.J.2    Pedersen, R.A.3
  • 80
    • 0028088752 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development. (I) Craniofacial and skeletal abnormalities in RAR double mutants
    • LOHNES, D., MARK, M , MENDELSOHN, C., DOLLÉ, P., DIERICH, A., GORRY, P., GANSMULLER, A. and CHAMBON, P (1994). Function of the retinoic acid receptors (RARs) during development. (I) Craniofacial and skeletal abnormalities in RAR double mutants Development 120: 2723-2748.
    • (1994) Development , vol.120 , pp. 2723-2748
    • Lohnes, D.1    Mark, M.2    Mendelsohn, C.3    Dollé, P.4    Dierich, A.5    Gorry, P.6    Gansmuller, A.7    Chambon, P.8
  • 81
    • 0024539888 scopus 로고
    • Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly
    • MACDONALD, K.B., JURILOFF, D M. and HARRIS, M.J. (1989). Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly. Teratology 39: 195-213
    • (1989) Teratology , vol.39 , pp. 195-213
    • Macdonald, K.B.1    Juriloff, D.M.2    Harris, M.J.3
  • 82
    • 0029019627 scopus 로고
    • Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants
    • MARTÍ, E., BUMCROT, D.A , TAKADA, R. and MCMAHON, A.P. (1995). Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature 375: 322-325.
    • (1995) Nature , vol.375 , pp. 322-325
    • Martí, E.1    Bumcrot, D.A.2    Takada, R.3    Mcmahon, A.P.4
  • 83
    • 0025188130 scopus 로고
    • The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
    • MCMAHON, A.P. and BRADLEY, A (1990). The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62: 1073-1085.
    • (1990) Cell , vol.62 , pp. 1073-1085
    • Mcmahon, A.P.1    Bradley, A.2
  • 85
    • 0026052275 scopus 로고
    • N-CAM alterations in splotch neural tube defect mouse embryos
    • MOASE, C.E. and TRASLER, D.G. (1991). N-CAM alterations in splotch neural tube defect mouse embryos. Development 113: 1049-1058
    • (1991) Development , vol.113 , pp. 1049-1058
    • Moase, C.E.1    Trasler, D.G.2
  • 86
    • 0023261399 scopus 로고
    • Effect on rat embryos of in vitro culture in sera from human diabetic patients
    • MOORE, D.C., STANISSTREET, M , CLARKE, C A., BECK, F and HIPKIN, L.J. (1987). Effect on rat embryos of in vitro culture in sera from human diabetic patients. Diabetes Res. 5: 139-143.
    • (1987) Diabetes Res. , vol.5 , pp. 139-143
    • Moore, D.C.1    Stanisstreet, M.2    Clarke, C.A.3    Beck, F.4    Hipkin, L.J.5
  • 87
    • 0025322679 scopus 로고
    • The role of the mesenchyme in mouse neural fold elevation II Patterns of hyaluronate synthesis and distribution in embryos developing in vitro
    • MORRIS-WIMAN, J. and BRINKLEY, L.L. (1990a). The role of the mesenchyme in mouse neural fold elevation II Patterns of hyaluronate synthesis and distribution in embryos developing in vitro. Am. J. Anat. 188: 133-147.
    • (1990) Am. J. Anat. , vol.188 , pp. 133-147
    • Morris-Wiman, J.1    Brinkley, L.L.2
  • 88
    • 0025349934 scopus 로고
    • Changes in mesenchymal cell and hyaluronate distribution correlate with in vivo elevation of the mouse mesencephalic neural folds
    • MORRIS-WIMAN, J. and BRINKLEY, L.L. (1990b) Changes in mesenchymal cell and hyaluronate distribution correlate with in vivo elevation of the mouse mesencephalic neural folds. Anat. Rec. 226: 383-395
    • (1990) Anat. Rec. , vol.226 , pp. 383-395
    • Morris-Wiman, J.1    Brinkley, L.L.2
  • 89
    • 0025312625 scopus 로고
    • The role of the mesenchyme in mouse neural fold elevation I. Patterns of mesenchymal cell distribution and proliferation in embryos developing in vitro
    • MORRIS-WIMAN, J. and BRINKLEY, L.L. (1990c). The role of the mesenchyme in mouse neural fold elevation I. Patterns of mesenchymal cell distribution and proliferation in embryos developing in vitro. Am. J. Anat. 188: 121-132.
    • (1990) Am. J. Anat. , vol.188 , pp. 121-132
    • Morris-Wiman, J.1    Brinkley, L.L.2
  • 90
    • 0020046530 scopus 로고
    • Culture of rat embryos with B-D-xyloside:evidence of a role for proteoglycans in neurulation
    • MORRISS-KAY, G.M. and CRUTCH, B. (1982). Culture of rat embryos with B-D-xyloside:evidence of a role for proteoglycans in neurulation. J. Anat. 134: 491-506.
    • (1982) J. Anat. , vol.134 , pp. 491-506
    • Morriss-Kay, G.M.1    Crutch, B.2
  • 91
    • 0018198741 scopus 로고
    • Regional differences in mesenchymal cell morphology and glycosaminoglycans in early neural-fold stage rat embryos
    • MORRISS, G M. and SOLURSH, M. (1978a) Regional differences in mesenchymal cell morphology and glycosaminoglycans in early neural-fold stage rat embryos. J. Embryol Exp. Morphol 46: 37-52.
    • (1978) J. Embryol Exp. Morphol , vol.46 , pp. 37-52
    • Morriss, G.M.1    Solursh, M.2
  • 92
    • 1842288286 scopus 로고
    • The role of primary mesenchyme in normal and abnormal morphogenesis of mammalian neural folds
    • MORRISS, G.M. and SOLURSH, M. (1978b). The role of primary mesenchyme in normal and abnormal morphogenesis of mammalian neural folds. Zoon 6: 33-38.
    • (1978) Zoon , vol.6 , pp. 33-38
    • Morriss, G.M.1    Solursh, M.2
  • 93
    • 0022273461 scopus 로고
    • The role of microfilaments in cranial neurulation in rat embryos: Effects of short-term exposure to cytochalasin D
    • MORRISS-KAY, G.M. and TUCKETT, F (1985). The role of microfilaments in cranial neurulation in rat embryos: effects of short-term exposure to cytochalasin D J. Embryo! Exp. Morphol. 88: 333-348.
    • (1985) J. Embryo! Exp. Morphol. , vol.88 , pp. 333-348
    • Morriss-Kay, G.M.1    Tuckett, F.2
  • 94
    • 0024424189 scopus 로고
    • Immunohistochemical localisation of chondroitin sulphate proteoglycans and the effects of chondroitinase ABC in 9- To 11-day rat embryos
    • MORRISS-KAY, G.M and TUCKETT, F. (1989). Immunohistochemical localisation of chondroitin sulphate proteoglycans and the effects of chondroitinase ABC in 9- to 11-day rat embryos. Development 106: 787-798.
    • (1989) Development , vol.106 , pp. 787-798
    • Morriss-Kay, G.M.1    Tuckett, F.2
  • 95
    • 0022924541 scopus 로고
    • The effects of Streptomyces hyaluronidase on tissue organization and cell cycle time in rat embryos
    • MORRISS-KAY, G.M, TUCKETT, F. and SOLURSH, M. (1986). The effects of Streptomyces hyaluronidase on tissue organization and cell cycle time in rat embryos J. Embryol Exp. Morphol. 98: 59-70.
    • (1986) J. Embryol Exp. Morphol. , vol.98 , pp. 59-70
    • Morriss-Kay, G.M.1    Tuckett, F.2    Solursh, M.3
  • 96
    • 0027176228 scopus 로고
    • Constitutive activation of Src family kinases in mouse embryos that lack Csk
    • NADA, S , YAGI, T., TAKEDA, H., TOKUNAGA, T., NAKAGAWA, H., IKAWA, Y., OKADA, M. and AIZAWA, S. (1993) Constitutive activation of Src family kinases in mouse embryos that lack Csk. Cell 73 1125-1135.
    • (1993) Cell , vol.73 , pp. 1125-1135
    • Nada, S.1    Yagi, T.2    Takeda, H.3    Tokunaga, T.4    Nakagawa, H.5    Ikawa, Y.6    Okada, M.7    Aizawa, S.8
  • 97
    • 33747563274 scopus 로고
    • Studies on the mechanisms of neurulation in the chick: Microfilament-mediated changes in cell shape during uplifting of neural folds
    • NAGELE, R.G and LEE, H (1980) Studies on the mechanisms of neurulation in the chick: microfilament-mediated changes in cell shape during uplifting of neural folds. J. Exp Zool 213 391-398
    • (1980) J. Exp Zool , vol.213 , pp. 391-398
    • Nagele, R.G.1    Lee, H.2
  • 98
    • 0017928819 scopus 로고
    • Whole-embryo culture and the study of mammalian embryos during organogenesis
    • NEW, D.A.T. (1978) Whole-embryo culture and the study of mammalian embryos during organogenesis. Biol. Rev. 53: 81-122.
    • (1978) Biol. Rev. , vol.53 , pp. 81-122
    • New, D.A.T.1
  • 99
    • 0026492351 scopus 로고
    • Methionine decreases the embryotoxicity of sodium valproate in the rat: In vivo and in vitro observations
    • NOSEL, P.G. and KLEIN, N.W (1992) Methionine decreases the embryotoxicity of sodium valproate in the rat: in vivo and in vitro observations. Teratology 46. 499-507
    • (1992) Teratology , vol.46 , pp. 499-507
    • Nosel, P.G.1    Klein, N.W.2
  • 100
    • 8244257072 scopus 로고
    • Tunicamycin-induced defects in the mouse embryo an in vitro study
    • (Eds. S R. Hawkes and J.L. Wang). Academic Press, New York
    • O'SHEA, K.S. (1982) Tunicamycin-induced defects in the mouse embryo an in vitro study. In Extracellular Matrix (Eds. S R. Hawkes and J.L. Wang). Academic Press, New York, pp 147-151.
    • (1982) Extracellular Matrix , pp. 147-151
    • O'Shea, K.S.1
  • 101
    • 8244224272 scopus 로고
    • Type IV collagen in neurulation
    • O'SHEA, K S (1986). Type IV collagen in neurulation Soc. Neurosci Abstr. 12: 316
    • (1986) Soc. Neurosci Abstr. , vol.12 , pp. 316
    • O'Shea, K.S.1
  • 102
    • 0019302108 scopus 로고
    • Phospholipase C induced neural tube defects in the mouse embryo
    • O'SHEA, K S and KAUFMAN, M.H. (1980). Phospholipase C induced neural tube defects in the mouse embryo. Experientia 36: 1217-1219
    • (1980) Experientia , vol.36 , pp. 1217-1219
    • O'Shea, K.S.1    Kaufman, M.H.2
  • 104
    • 0030068399 scopus 로고    scopus 로고
    • Relationship between altered axial curvature and neural tube closure in normal and mutant (curly tail) mouse embryos
    • PEETERS, M.C.E., SHUM, A S.W., HEKKING, J.W.M., COPP, A J. and VAN STRAATEN, H.W.M. (1996) Relationship between altered axial curvature and neural tube closure in normal and mutant (curly tail) mouse embryos. Anat. Embryol. 193: 123-130.
    • (1996) Anat. Embryol. , vol.193 , pp. 123-130
    • Peeters, M.C.E.1    Shum, A.S.W.2    Hekking, J.W.M.3    Copp, A.J.4    Van Straaten, H.W.M.5
  • 106
    • 0022578670 scopus 로고
    • Yolk sac failure in embryopathy due to hyperglycemia: Ultrastructural analysis of yolk sac differentiation associated with embryopathy in rat conceptuses under hyperglycemic conditions
    • PINTER, E., REECE, E.A., LERANTH, C.Z., SANYAL, M.K , HOBBINS, J.C., MAHONEY, M J. and NAFTOLIN, F (1986b). Yolk sac failure in embryopathy due to hyperglycemia: ultrastructural analysis of yolk sac differentiation associated with embryopathy in rat conceptuses under hyperglycemic conditions. Teratology 33: 73-84
    • (1986) Teratology , vol.33 , pp. 73-84
    • Pinter, E.1    Reece, E.A.2    Leranth, C.Z.3    Sanyal, M.K.4    Hobbins, J.C.5    Mahoney, M.J.6    Naftolin, F.7
  • 107
    • 0024208690 scopus 로고
    • Fatty acid content of yolk sac and embryo in hyperglycemia-induced embryopathy and effect of arachidonic acid supplementation
    • PINTER, E , REECE, E.A., OGBURN, P L.J., TURNER, S., HOBBINS, J C., MAHONEY, M.J. and NAFTOLIN, F. (1988) Fatty acid content of yolk sac and embryo in hyperglycemia-induced embryopathy and effect of arachidonic acid supplementation Am. J. Obstet. Gynecol. 159: 1484-1490
    • (1988) Am. J. Obstet. Gynecol. , vol.159 , pp. 1484-1490
    • Pinter, E.1    Reece, E.A.2    Ogburn, P.L.J.3    Turner, S.4    Hobbins, J.C.5    Mahoney, M.J.6    Naftolin, F.7
  • 108
    • 0023748489 scopus 로고
    • The effect of epidermal growth factor, insulin and transferrin on the growth-promoting properties of serum depleted by repeated culture of postimplantation rat embryos
    • PRATTEN, M K., BROOKE, A.M., BROOME, S.C. and BECK, F. (1988) The effect of epidermal growth factor, insulin and transferrin on the growth-promoting properties of serum depleted by repeated culture of postimplantation rat embryos. Development 104: 137-145.
    • (1988) Development , vol.104 , pp. 137-145
    • Pratten, M.K.1    Brooke, A.M.2    Broome, S.C.3    Beck, F.4
  • 109
    • 0028836857 scopus 로고
    • Neuroectodermal fate of epiblast cells in the distal region of the mouse egg cylinder: Implication for body plan organization during early embryogenesis
    • QUINLAN, G A., WILLIAMS, E.A ,TAN. S.-S. and TAM, P.P L.(1995). Neuroectodermal fate of epiblast cells in the distal region of the mouse egg cylinder: implication for body plan organization during early embryogenesis. Development 121: 87-98.
    • (1995) Development , vol.121 , pp. 87-98
    • Quinlan, G.A.1    Williams, E.A.2    Tan, S.-S.3    Tam, P.P.L.4
  • 111
    • 0029004233 scopus 로고
    • Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of Sonic hedgehog autoproteolysis
    • ROELINK, H , PORTER, J.A , CHIANG, C., TANABE, Y., CHANG, D.T.. BEACHY, P.A. and JESSELL, T.M. (1995). Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of Sonic hedgehog autoproteolysis. Cell 81: 445-455
    • (1995) Cell , vol.81 , pp. 445-455
    • Roelink, H.1    Porter, J.A.2    Chiang, C.3    Tanabe, Y.4    Chang, D.T.5    Beachy, P.A.6    Jessell, T.M.7
  • 112
    • 0018196279 scopus 로고
    • Investigation of the potency of cells from the postimplantation mouse embryo by blastocyst injection: A preliminary report
    • ROSSANT, J., GARDNER, R.L. and ALEXANDRE, H.L. (1978). Investigation of the potency of cells from the postimplantation mouse embryo by blastocyst injection: a preliminary report J. Embryol. Exp. Morphol. 48: 239-247
    • (1978) J. Embryol. Exp. Morphol. , vol.48 , pp. 239-247
    • Rossant, J.1    Gardner, R.L.2    Alexandre, H.L.3
  • 113
    • 0017893770 scopus 로고
    • Distribution of surface coat material on fusing neural folds of mouse embryos during neurulation
    • SADLER, T.W. (1978). Distribution of surface coat material on fusing neural folds of mouse embryos during neurulation. Anat. Rec. 191. 345-350
    • (1978) Anat. Rec. , vol.191 , pp. 345-350
    • Sadler, T.W.1
  • 115
    • 0029146386 scopus 로고
    • Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos
    • SADLER, T.W., LIU, E.T. and AUGUSTINE, K.A (1995). Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos. Teratology 51. 292-299.
    • (1995) Teratology , vol.51 , pp. 292-299
    • Sadler, T.W.1    Liu, E.T.2    Augustine, K.A.3
  • 118
    • 0025364510 scopus 로고
    • Mechanisms of neurulation: Traditional viewpoint and recent advances
    • SCHOENWOLF, G.C and SMITH, J.L (1990). Mechanisms of neurulation: traditional viewpoint and recent advances. Development 109: 243-270
    • (1990) Development , vol.109 , pp. 243-270
    • Schoenwolf, G.C.1    Smith, J.L.2
  • 119
    • 0025977816 scopus 로고
    • Morphological differences elicited by two weak acids, retinoic and valproic, in rat embryos grown in vitro
    • SEEGMILLER, R.E., HARRIS, C., LUCHTEL, D.L. and JUCHAU, M.R. (1991). Morphological differences elicited by two weak acids, retinoic and valproic, in rat embryos grown in vitro. Teratology 43: 133-150.
    • (1991) Teratology , vol.43 , pp. 133-150
    • Seegmiller, R.E.1    Harris, C.2    Luchtel, D.L.3    Juchau, M.R.4
  • 120
    • 0028964641 scopus 로고
    • Further evidence for an intermittent pattern of neural tube closure in humans
    • SELLER, M.J (1995) Further evidence for an intermittent pattern of neural tube closure in humans. J Med. Genet 32. 205-207
    • (1995) J Med. Genet , vol.32 , pp. 205-207
    • Seller, M.J.1
  • 121
    • 0020957147 scopus 로고
    • Effect of hydroxyurea on neural tube defects in the curly-tail mouse
    • SELLER, M.J. and PERKINS, K J. (1983). Effect of hydroxyurea on neural tube defects in the curly-tail mouse. J Craniofac. Genet Dev. Biol. 3: 11-17
    • (1983) J Craniofac. Genet Dev. Biol. , vol.3 , pp. 11-17
    • Seller, M.J.1    Perkins, K.J.2
  • 122
    • 0022538284 scopus 로고
    • Effect of mitomycin C on the neural tube defects of the curly-tail mouse
    • SELLER, M.J and PERKINS, K.J. (1986) Effect of mitomycin C on the neural tube defects of the curly-tail mouse. Teratology 33: 305-309.
    • (1986) Teratology , vol.33 , pp. 305-309
    • Seller, M.J.1    Perkins, K.J.2
  • 123
    • 0030007578 scopus 로고    scopus 로고
    • Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse
    • SHUM, A.S.W and COPP, A J. (1996). Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse. Anat Embryol. 194: 65-73.
    • (1996) Anat Embryol. , vol.194 , pp. 65-73
    • Shum, A.S.W.1    Copp, A.J.2
  • 126
    • 0023227261 scopus 로고
    • Cell cycle and neuroepithelial cell shape during bending of the chick neural plate
    • SMITH, J.L. and SCHOENWOLF, G.C. (1987). Cell cycle and neuroepithelial cell shape during bending of the chick neural plate Anat. Rec. 218: 196-206.
    • (1987) Anat. Rec. , vol.218 , pp. 196-206
    • Smith, J.L.1    Schoenwolf, G.C.2
  • 127
    • 0023883336 scopus 로고
    • Role of cell-cycle in regulating neuroepithelial cell shape during bending of the chick neural plate
    • SMITH, J.L. and SCHOENWOLF, G.C. (1988). Role of cell-cycle in regulating neuroepithelial cell shape during bending of the chick neural plate. Cell Tissue Res. 252: 491-500.
    • (1988) Cell Tissue Res. , vol.252 , pp. 491-500
    • Smith, J.L.1    Schoenwolf, G.C.2
  • 128
    • 0028090122 scopus 로고
    • Prospective fate map of the mouse primitive streak at 7.5 days of gestation
    • SMITH, J L , GESTELAND, K M. and SCHOENWOLF, G.C (1994). Prospective fate map of the mouse primitive streak at 7.5 days of gestation. Dev. Dynamics 201: 279-289.
    • (1994) Dev. Dynamics , vol.201 , pp. 279-289
    • Smith, J.L.1    Gesteland, K.M.2    Schoenwolf, G.C.3
  • 130
    • 0017581481 scopus 로고
    • Glycosaminoglycan synthesis in rat embryos during the formation of the primary mesenchyme and neural folds
    • SOLURSH, M. and MORRISS, G.M. (1977). Glycosaminoglycan synthesis in rat embryos during the formation of the primary mesenchyme and neural folds. Dev. Biol. 57: 75-86.
    • (1977) Dev. Biol. , vol.57 , pp. 75-86
    • Solursh, M.1    Morriss, G.M.2
  • 132
    • 0026718857 scopus 로고
    • Phosphoinositide metabolism in the developing conceptus Effects of hyperglycemia and scylloinositol in rat embryo culture
    • STRIELEMAN, P.J., CONNORS, M A. and METZGER, B.E. (1992). Phosphoinositide metabolism in the developing conceptus Effects of hyperglycemia and scylloinositol in rat embryo culture. Diabetes 41: 989-997.
    • (1992) Diabetes , vol.41 , pp. 989-997
    • Strieleman, P.J.1    Connors, M.A.2    Metzger, B.E.3
  • 133
    • 0028883213 scopus 로고
    • MARCKS deficiency in mice leads to abnormal brain development and perinatal death
    • STUMPO, D.J., BOCK, C.B , TUTTLE, J.S. and BLACKSHEAR, P.J. (1995) MARCKS deficiency in mice leads to abnormal brain development and perinatal death. Proc. Natl Acad. Sci. USA 92: 944-948.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 944-948
    • Stumpo, D.J.1    Bock, C.B.2    Tuttle, J.S.3    Blackshear, P.J.4
  • 134
    • 0026478723 scopus 로고
    • Development of rat embryos in culture media containing different concentrations of normal and diabetic rat serum
    • STYRUD, J. and ERIKSSON, U.J (1992) Development of rat embryos in culture media containing different concentrations of normal and diabetic rat serum. Teratology 46: 473-483.
    • (1992) Teratology , vol.46 , pp. 473-483
    • Styrud, J.1    Eriksson, U.J.2
  • 137
    • 0024458025 scopus 로고
    • Regionalisation of the mouse embryonic ectoderm allocation of prospective ectodermal tissues during gastrulation
    • TAM, P.P.L. (1989). Regionalisation of the mouse embryonic ectoderm allocation of prospective ectodermal tissues during gastrulation. Devetopment 107: 55-67.
    • (1989) Devetopment , vol.107 , pp. 55-67
    • Tam, P.P.L.1
  • 138
    • 0026451739 scopus 로고
    • Establishment and organization of germ layers in the gastrulating mouse embryo
    • (Eds. D J Chadwick and J. Marsh) John Wiley and Sons, New York
    • TAM, P.P.L. and BEDDINGTON, R.S.P (1992) Establishment and organization of germ layers in the gastrulating mouse embryo. In Postimplantation Development in the Mouse (Ciba Foundation Symposium) (Eds. D J Chadwick and J. Marsh) John Wiley and Sons, New York, pp. 27-49
    • (1992) Postimplantation Development in the Mouse (Ciba Foundation Symposium) , pp. 27-49
    • Tam, P.P.L.1    Beddington, R.S.P.2
  • 139
    • 0025074908 scopus 로고
    • Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbram and cerebellar development
    • THOMAS, K.R and CAPECCHI, M.R. (1990). Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbram and cerebellar development. Nature 346: 847-850.
    • (1990) Nature , vol.346 , pp. 847-850
    • Thomas, K.R.1    Capecchi, M.R.2
  • 140
    • 0027730439 scopus 로고
    • Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system
    • TOMASIEWICZ, H., ONO, K., YEE, D., THOMPSON, C., GORIDIS, C , RUTISHAUSER, U and MAGNUSON, T. (1993). Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system Neuron 11: 1163-1174.
    • (1993) Neuron , vol.11 , pp. 1163-1174
    • Tomasiewicz, H.1    Ono, K.2    Yee, D.3    Thompson, C.4    Goridis, C.5    Rutishauser, U.6    Magnuson, T.7
  • 141
    • 0026001235 scopus 로고
    • Immunohistochemical localization of chondroitin and heparan sulfate proteoglycans in pre-spina bifida splotch mouse embryos
    • TRASLER, D G and MORRISS-KAY, G (1991). Immunohistochemical localization of chondroitin and heparan sulfate proteoglycans in pre-spina bifida splotch mouse embryos. Teratology 44: 571-579.
    • (1991) Teratology , vol.44 , pp. 571-579
    • Trasler, D.G.1    Morriss-Kay, G.2
  • 142
    • 0023225405 scopus 로고
    • Valproic acid-induced neural tube defects. reduction by folinic acid in the mouse
    • TROTZ, M., WEGNER, C and NAU, H. (1987). Valproic acid-induced neural tube defects. reduction by folinic acid in the mouse. Life Sci. 41: 103-110.
    • (1987) Life Sci. , vol.41 , pp. 103-110
    • Trotz, M.1    Wegner, C.2    Nau, H.3
  • 143
    • 0022556443 scopus 로고
    • The distribution of fibronectin, laminin and entactin in the neurulating rat embryo studied by indirect immunofiuorescence
    • TUCKETT, F and MORRISS-KAY, G.M (1986). The distribution of fibronectin, laminin and entactin in the neurulating rat embryo studied by indirect immunofiuorescence. J. Embryol. Exp. Morphol 94: 95-112.
    • (1986) J. Embryol. Exp. Morphol , vol.94 , pp. 95-112
    • Tuckett, F.1    Morriss-Kay, G.M.2
  • 144
    • 0024343658 scopus 로고
    • Heparitinase treatment of rat embryos during cranial neurulation
    • TUCKETT, F and MORRISS-KAY, G.M (1989). Heparitinase treatment of rat embryos during cranial neurulation. Anat. Embryol. 180: 393-400
    • (1989) Anat. Embryol. , vol.180 , pp. 393-400
    • Tuckett, F.1    Morriss-Kay, G.M.2
  • 145
    • 0025355724 scopus 로고
    • Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate
    • TURNER, S., SUCHESTON, M.E., DE PHILIP, R.M and PAULSON, R B. (1990). Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate. Teratology 41. 421-442.
    • (1990) Teratology , vol.41 , pp. 421-442
    • Turner, S.1    Sucheston, M.E.2    De Philip, R.M.3    Paulson, R.B.4
  • 147
    • 0027446956 scopus 로고
    • Intrinsic and extrinsic factors in the mechanism of neurulation. effect of curvature of the body axis on closure of the posterior neuropore
    • VAN STRAATEN, H W.M., HEKKING, J W M., CONSTEN, C and COPP, A J. (1993). Intrinsic and extrinsic factors in the mechanism of neurulation. effect of curvature of the body axis on closure of the posterior neuropore. Development 117: 1163-1172
    • (1993) Development , vol.117 , pp. 1163-1172
    • Van Straaten, H.W.M.1    Hekking, J.W.M.2    Consten, C.3    Copp, A.J.4
  • 148
    • 0022263235 scopus 로고
    • Effect of a notochordal implant on the early morphogenesis of the neural tube and neuroblasts. histometrical and histological results
    • VAN STRAATEN, H.W.M., THORS, F., WIERTZ-HOESSELS, J., HEKKING, J and DRUKKER, J. (1985). Effect of a notochordal implant on the early morphogenesis of the neural tube and neuroblasts. histometrical and histological results. Dev. Biol 110: 247-254.
    • (1985) Dev. Biol , vol.110 , pp. 247-254
    • Van Straaten, H.W.M.1    Thors, F.2    Wiertz-Hoessels, J.3    Hekking, J.4    Drukker, J.5
  • 150
    • 0028019410 scopus 로고
    • Gene inhibition using antisense oligodeoxynucleotides
    • WAGNER, R W. (1994). Gene inhibition using antisense oligodeoxynucleotides. Nature 372: 333-335.
    • (1994) Nature , vol.372 , pp. 333-335
    • Wagner, R.W.1
  • 151
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • WALD, N., SNEDDON, J., DENSEM, J., FROST, C., STONE, R and MRC VITAMIN STUDY RES GROUP (1991). Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338: 131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
    • Wald, N.1    Sneddon, J.2    Densem, J.3    Frost, C.4    Stone, R.5
  • 152
    • 0026302402 scopus 로고
    • Diurnal variation of folate concentrations in mouse embryo and plasma: The protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent
    • WEGNER, C and NAU, H. (1991). Diurnal variation of folate concentrations in mouse embryo and plasma: the protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent. Reproof. Toxicol. 5. 465-471.
    • (1991) Reproof. Toxicol. , vol.5 , pp. 465-471
    • Wegner, C.1    Nau, H.2
  • 153
    • 0026848306 scopus 로고
    • Alteration of embryonic folate metabolism by valproic acid during organogenesis: Implications for mechanism of teratogenesis
    • WEGNER, C. and NAU, H. (1992). Alteration of embryonic folate metabolism by valproic acid during organogenesis: implications for mechanism of teratogenesis. Neurology 42 (Suppl 5): 17-24
    • (1992) Neurology , vol.42 , Issue.5 SUPPL. , pp. 17-24
    • Wegner, C.1    Nau, H.2
  • 155
    • 0018976329 scopus 로고
    • The effects of cytochalasins on the ultrastructure of neurulating hamster embryos in vivo
    • WILEY, M.J. (1980). The effects of cytochalasins on the ultrastructure of neurulating hamster embryos in vivo. Teratology 22: 59-69.
    • (1980) Teratology , vol.22 , pp. 59-69
    • Wiley, M.J.1
  • 156
    • 0023623376 scopus 로고
    • Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo
    • WILKINSON, D.G , BAILES, J.A. and MCMAHON, A.P. (1987). Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo Cell 50: 79-88.
    • (1987) Cell , vol.50 , pp. 79-88
    • Wilkinson, D.G.1    Bailes, J.A.2    Mcmahon, A.P.3
  • 157
    • 9044254925 scopus 로고    scopus 로고
    • Neural tube defects and abnormal brain development in F52-deficientmice
    • WU, M., CHEN, D.F., SASAOKA, T. and TONEGAWA, S. (1996) Neural tube defects and abnormal brain development in F52-deficientmice. Proc. Natl. Acad. Sci. USA 93: 2110-2115.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2110-2115
    • Wu, M.1    Chen, D.F.2    Sasaoka, T.3    Tonegawa, S.4
  • 158
    • 0027364045 scopus 로고
    • Inhibition of differentiation in P19 embryonal carcinoma cells by the expression of vectors encoding truncated or antisense EGF receptor
    • WU, J-X. and ADAMSON, E.D. (1993). Inhibition of differentiation in P19 embryonal carcinoma cells by the expression of vectors encoding truncated or antisense EGF receptor. Dev. Biol 159: 208-222
    • (1993) Dev. Biol , vol.159 , pp. 208-222
    • Wu, J.-X.1    Adamson, E.D.2
  • 159
    • 0028310311 scopus 로고
    • Multiple developmental defects in Engrailed-1 mutant mice: An early mid-hindbrain deletion and patterning defects in forelimbs and sternum
    • WURST, W , AUERBACH, A.B. and JOYNER, A.L. (1994) Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development 120. 2065-2075.
    • (1994) Development , vol.120 , pp. 2065-2075
    • Wurst, W.1    Auerbach, A.B.2    Joyner, A.L.3


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