Inhibitory effect of caffeic acid phenethyl ester on human leukemia HL-60 cells

Cancer Letters

Volumn 108, Issue 2, 1996, Pages 211-214

  Chen, Jian Hong ^a   Shao, Yu ^a   Huang, Mou Tuan ^b   Chin, Chee Kok ^a   Ho, Chi Tang ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Antitumor; Caffeic acid; Caffeic acid phenethyl ester; HL 60 cells; Propolis

Indexed keywords

CAFFEIC ACID DERIVATIVE; DICYCLOHEXYLCARBODIIMIDE; DNA; PHENETHYL ALCOHOL; PROTEIN; RNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RNA SYNTHESIS;

ANTICARCINOGENIC AGENTS; CAFFEIC ACIDS; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; PHENYLETHYL ALCOHOL;

PROPOLIS;

EID: 0030606290     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04425-4     Document Type: Article

References (16)

1. [1] Kujumgiev, A., Bankova, V.B., Ignatova, A. and Popov, S. (1993) Antibacterial activity of propolis, some of its compounds and their analogs, Pharmazic, 48, 785-786.
2. [2] Focht, J., Hansen, S.H., Nielsen, J.V., van den Berg-Segers, A. and Riezler, R. (1993) Bactericidal effect of propolis in vitro against agents causing upper respiratory tract infections, Arzneim.-Forsch., 43, 921-923.
3. [3] Khayyal, M.T., El-Ghazaly, M.A. and El-Khatib, A.S. (1993) Mechanisms involved in the antiinnammatory effect of propolis extract, Drugs Under Exp. Clin. Res., 19, 197-203.
4. [4] Rao, C.V., Desai, D., Simi, B., Kulkarni, N., Amin, A. and Reddy, B.S. (1993) Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon, Cancer Res., 53, 4182-4188.
5. [5] Mirzoeva, O.K., Sud'ina, G.F., Pushkareva, M.A., Korshimova, G.A., Sumbatian, N.V. and Varfolomeev, S.D. (1995) Lipophilic derivatives of caffeic acid as lipoxygenase inhibitors with antioxidant properties, Bioorg. Khim., 21, 143-151.
6. [6] Rao, C. V, Desai, D., Rivenson, A., Simi, B., Amin, S. and Reddy, B.S. (1995) Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate, Cancer Res., 55, 2310-2315.
7. [7] Su, Z.Z., Lin, J., Grunberger, D. and Fisher, P.B. (1994) Growth suppression and toxicity induced by caffeic acid phenethyl ester(CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression, Cancer Res., 54, 1865-1870.
8. [8] Frenkel, K., Wei, H., Bhimani, R., Ye, J., Zadunaiasky, J.A., Huang, M.T., Ferraro, T., Conny, A.H. and Grunberger, D. (1993) Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester, Cancer Res., 53, 1255-1261.
9. [9] Grunberger, D., Banerjee, R., Eisinger, K., Okz, E.M., Efros, L., Caldwell, M., Estevez, V. and Nakanishi, K. (1988) Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis, Experientia, 44, 230-232.
10. [10] Rao, C.V., Desai, D., Kaul, B., Amin, S. and Reddy, B.S. (1992) Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth, Chem. Biol. Interactions, 84, 277-290.
11. [11] Hassner, A. and Alexanian, V. (1978) Direct room temperature esterification of carboxylic acids, Tetrahedron Lett., 46, 4475-4478.
12. [12] Neelakantan, S., Padmasani, R. and Seshadri, T.R. (1965) New reagents for the synthesis of despides, Tetrahedron, 21, 3531-3536.
13. [13] Shao, Y., Chin, C.K., Ho, C.T., Ma, W., Garrison, S.A. and Huang, M.T. (1996) Anti-tumor activity of the crude saponins obtained from asparagus, Cancer Lett., 104, 31-36.
14. [14] Su, Z.Z., Lin, J., Prewett, M., Goldstein, N.Z. and Fisher, P.B. (1995) Apoptosis mediates the selective toxicity of caffeic acid phenethyl ester (CAPE) toward oncogene-transformed rat embryo fibroblast cells, Anticancer Res., 15, 1841-1848.
15. [15] Su, Z.Z., Grunberger, D. and Fisher, P.B. (1991) Suppression of adenovirus type 5 E1A-mediated transformation and expression of the transformed phenotype by caffeic acid phenethyl ester (CAPE), Mol. Carcinogenesis, 4, 231-242.
16. [16] Guarini, L., Su, Z.Z., Zucker, S., Lin, J., Grunberger, D. and Fisher, P.B. (1992) Growth inhibition and modulation of antigenie phenotype in human melanoma and glioblastoma multiforme cells by caffeic acid phenethyl ester (CAPE), Cell. Mol. Biol., 38, 513-527.