The hcKrox gene family regulates multiple extracellular matrix genes

Matrix Biology

Volumn 20, Issue 7, 2001, Pages 451-462

  Widom, Russell L ^a   Lee, John Y ^a   Joseph, Cuthbert ^a   Gordon Froome, Ingrid ^a   Korn, Joseph H ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Collagen; Elastin; Fibronectin; hcKrox; Matrix; Transcription factor

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 1ALPHA; COLLAGEN TYPE 2; COLLAGEN TYPE 2ALPHA; COMPLEMENTARY DNA; ELASTIN; FIBRONECTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HCKROX ALPHA; TRANSCRIPTION FACTOR HCKROX BETA; TRANSCRIPTION FACTOR HCKROX GAMMA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; ELECTROPHORETIC MOBILITY; EXTRACELLULAR MATRIX; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; MULTIGENE FAMILY; NONHUMAN; PREPUCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COLLAGEN TYPE I; COS CELLS; DIMERIZATION; DNA; DNA-BINDING PROTEINS; ELASTIN; FIBRONECTINS; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; ZINC FINGERS;

EID: 0034751611     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(01)00167-6     Document Type: Article

References (29)

1. The POZ domain: A conserved protein-protein interaction motif
2. Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes
3. Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene
4. Regulation of fibronectin biosynthesis by dexamethasone, transforming growth factor-b and cAMP in human cell lines
5. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein
6. c-Krox binds to several sites in the promoter of both mouse type I collagen genes
7. Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration
8. Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia
9. Sp1-mediated transcriptional activation is repressed by Sp3
10. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia
11. A rapid microscale procedure for the simultaneous preparation of cytoplasmic RNA, nuclear DNA binding proteins and enzymatically active luciferase extracts
12. Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element
13. Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts
14. Functional analysis of human alpha 1(I) procollagen gene promoter. Differential activity in collagen-producing and non-producing cells and response to transforming growth factor beta 1
15. Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis
16. Positive regulation of human α1(I) collagen promoter activity by transcription factor Sp1
17. Selective activation of transcription by a novel CCAAT binding factor
18. Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1
19. FBI-1, a factor that binds to the HIV-1 inducer of short transcripts (IST), is a POZ domain protein
20. Mithramycin selectively inhibits collagen-α1(I) gene expression in human fibroblasts
21. Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha1(I) promoter
22. APM-1, a novel human gene, identified by aberrant co-transcription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activity
23. Transactivation by retinoid X receptor-peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimers: Intermolecular synergy requires only the PPARgamma hormone-dependent activation function
24. Characterization of a GC-rich region containing Sp1 binding site(s) as a constitutive responsive element of the α2(I) collagen gene in human fibroblasts
25. Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions
26. Interferon-gamma reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor-b in normal human fibroblasts
27. Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression
28. Insulin-like growth factor-I regulates transcription of the elastin gene