Comparison of three methods for measuring PEG-hirudin in blood

Blood Coagulation and Fibrinolysis

Volumn 12, Issue 7, 2001, Pages 577-581

  Hoffmann, J J M L ^a   Janssen, W C M ^a  

^a CATHARINA HOSPITAL   (Netherlands)

Author keywords

Antithrombins; Ecarin; Hirudin; Point of care; Snake venoms; Thrombin inhibitor

Indexed keywords

ANTICOAGULANT AGENT; HEPARIN; HIRUDIN; LU 87981; MACROGOL;

ARTICLE; AUTOANALYSIS; BLOOD CLOTTING; CLINICAL ARTICLE; CLINICAL TRIAL; CORONARY ARTERY DISEASE; DRUG BLOOD LEVEL; DRUG MONITORING; HEMATOLOGICAL PARAMETERS; HUMAN; INTERMETHOD COMPARISON; LABORATORY TEST; PRIORITY JOURNAL; THROMBOSIS; UNSTABLE ANGINA PECTORIS;

ANTITHROMBINS; AUTOANALYSIS; BLOOD COAGULATION TESTS; CHROMOGENIC COMPOUNDS; COSTS AND COST ANALYSIS; DIPEPTIDES; HIRUDINS; HUMANS; INDICATORS AND REAGENTS; POINT-OF-CARE SYSTEMS; QUALITY CONTROL; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; THROMBIN;

EID: 0034748887     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200110000-00011     Document Type: Article

References (23)

1. Past, present and future of hirudin
2. Hirudin and hirudin analogues as new anticoagulant agents
3. Anticoagulation with r-hirudin in regular haemodialysis with heparin-induced thrombocytopenia (HIT II). The first long-term application of r-hirudin in a haemodialysis patient
4. Hirudin monitoring using the TAS ecarin clotting time in patients with heparin-induced thrombocytopenia type II
5. Monitoring anticoagulant therapy by activated partial thromboplastin time: Hirudin assessment. An evaluation of native blood and plasma assays
6. Monitoring of r-hirudin anticoagulation during cardiopulmonary bypass - Assessment of the whole blood ecarin clotting time
7. A quantitative thrombin time for determining levels of hirudin and Hirulog
8. Assay of hirudin in plasma using a chromogenic thrombin substrate
9. Development of a chromogenic substrate assay for the determination of hirudin in plasma
10. Evaluation of an automated chromogenic substrate assay for the rapid determination of hirudin in plasma
11. Quantitative determination of hirudin in blood and body fluids
12. Blood coagulation induced by the venom of Bothrops atrox. 1. Identification, purification, and properties of a prothrombin activator
13. Prothrombin conversion intermediate effectively neutralizes toxic levels of hirudin
14. Monitoring of recombinant hirudin: Assessment of a plasma-based ecarin clotting time assay
15. A quick assay for monitoring recombinant hirudin during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II: Adaptation of the ecarin clotting time to the ACT II device
16. Prevention of early reocclusion after thrombolysis of copper coil-induced thrombi in the canine carotid artery: Comparison of PEG-hirudin and unfractionated heparin
17. Dry-chemistry ecarin clotting time for ex vivo monitoring of thrombin inhibitors
18. Dry reagent technology for rapid, convenient measurements of blood coagulation and fibrinolysis
19. Laboratory assays for the evaluation of recombinant hirudin
20. Recombinant hirudin as a periprocedural antithrombotic in coronary angioplasty for unstable angina pectoris
21. Point-of-care fibrinolytic tests: The other side of blood coagulation
22. Interference of heparin and analogues with hirudin in the chromogenic thrombin substrate assay
23. Hirudin determination in plasma can be strongly influenced by the prothrombin level