Tissue factor and thrombomodulin levels are correlated with stage of cirrhosis in patients with liver disease

Blood Coagulation and Fibrinolysis

Volumn 12, Issue 7, 2001, Pages 539-545

  Tacke, F ^a   Schoffski P ^a   Trautwein, C ^a   Manns, M P ^a   Ganser, A ^a   Von Depka, Mario ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Bleeding; Liver cirrhosis; Thrombomodulin; Thrombosis; Tissue factor

Indexed keywords

THROMBOMODULIN; THROMBOPLASTIN;

ADULT; AGED; ARTICLE; CHRONIC LIVER DISEASE; DISEASE CLASSIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEMATOLOGICAL PARAMETERS; HUMAN; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THROMBOEMBOLISM;

ADOLESCENT; ADULT; AGED; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; FEMALE; HEMORRHAGE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PARTIAL THROMBOPLASTIN TIME; PLATELET COUNT; PROTHROMBIN TIME; REFERENCE VALUES; THROMBOEMBOLISM; THROMBOMODULIN; THROMBOPLASTIN;

EID: 0034747824     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200110000-00005     Document Type: Article

References (29)

1. Hepatic and portal vein thrombosis in cirrhosis: Possible role in development of parenchymal extinction and portal hypertension
2. Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients
3. Liver cirrhosis
4. Plasma thrombomodulin in health and disease
5. Determination of plasma tissue factor antigen and its clinical significance
6. The structural basis of function of the TF-VIIa complex in the cellular initiation of coagulation
7. The structural biology of expression and function of tissue factor
8. Activation of the factor VII-tissue factor pathway
9. Structural biology of tissue factor, the initiator of thrombogenesis in vivo
10. Tissue factor in health and disease
11. Tissue factor in the pathogenesis of atherosclerosis
12. Molecules in focus: Tissue factor
13. Thrombomodulin structure and function
14. Thrombomodulin found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblasts of human placenta
15. Identification of an endothelial cell cofactor for the thrombin-catalysed activation of protein C
16. Molecular mechanisms of thrombin function
17. Changes in regulating blood coagulation in hepatic resection with special references to soluble thrombomodulin and protein C
18. Lack of relationship between plasma thrombomodulin and portal hypertension in alcoholic liver disease
19. Cell biology of tissue factor, the principal initiator of blood coagulation
20. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
21. Cell biology of liver endothelial and Kupffer cells
22. Enhanced expression of monocyte tissue factor in patients with liver cirrhosis
23. Regulation of the tissue factor gene
24. Cytokine regulation of hemostatic property and IL-6 production of human endothelial cells
25. Release of thrombomodulin from endothelial cells by concerted action of TNF-α and neutrophils: In vivo and in vitro studies
26. A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes
27. Increased serum levels and sinusoidal expression of thrombomodulin in acute liver damage
28. Clinical and histological aspects of chronic HCV infection and cirrhosis
29. Effects of recombinant human soluble thrombomodulin (rhs-TM) on clot-induced coagulation in human plasma