Increase in myofibrillar Ca2+ sensitivity induced by UD-CG 212 Cl, an active metabolite of pimobendan, in canine ventricular myocardium

Journal of Cardiovascular Pharmacology

Volumn 37, Issue 2, 2001, Pages 209-218

  Takahashi, Reiko ^a   Endoh, Masao ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Ca2+ transients; cAMP; Dog; Myofibrillar Ca2+ sensitivity; Pimobendan; Positive inotropic effect; Ventricular muscle

Indexed keywords

AEQUORIN; CALCIUM; CARBACHOL; CYCLIC AMP; LEVOSIMENDAN; O NORPIMOBENDAN; PIMOBENDAN; CARDIOTONIC AGENT; PYRIDAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CONDUCTANCE; CALCIUM SIGNALING; CARDIOVASCULAR EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DRUG STRUCTURE; HEART VENTRICLE; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; ANIMAL; DOSE RESPONSE; DRUG EFFECT; FEMALE; HEART CONTRACTION; MALE; METABOLISM; MUSCLE FIBRIL; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CARBACHOL; CARDIOTONIC AGENTS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MYOCARDIAL CONTRACTION; MYOFIBRILS; PYRIDAZINES; SIGNAL TRANSDUCTION;

EID: 0034746346     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200102000-00008     Document Type: Article

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