P1/P1′ modified HIV protease inhibitors as tools in two new sensitive surface plasmon resonance biosensor screening assays

European Journal of Pharmaceutical Sciences

Volumn 13, Issue 2, 2001, Pages 203-212

  Alterman, M ^a   Sjobom, H ^a   Safsten, P ^a   Markgren, P O ^a   Danielson, U H ^a   Hamalainen, M ^a   Lofas, S ^a   Hulten, J ^a   Classon, B ^a   Samuelsson, B ^a   Hallberg, A ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Biosensor; HIV protease; HIV protease inhibitors; Screening; Surface plasmon resonance

Indexed keywords

ANTIBODIES; BIOASSAY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; HYDROLYSIS; SURFACE PLASMON RESONANCE;

PEPTIDES;

BIOSENSORS;

INDINAVIR; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR;

ARTICLE; ASSAY; BIOSENSOR; CHROMATOGRAPHY; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME BINDING; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMOBILIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; CHEMISTRY; CONFORMATION; DOSE RESPONSE; GENETIC PROCEDURES; METABOLISM; METHODOLOGY; SYNTHESIS;

BIOSENSING TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HIV PROTEASE; HIV PROTEASE INHIBITORS; MOLECULAR CONFORMATION; SURFACE PLASMON RESONANCE;

EID: 0034744992     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00109-9     Document Type: Article

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