Cyclin DI gene contains a cryptic promoter that is functional in human cancer cells

Genes Chromosomes and Cancer

Volumn 31, Issue 3, 2001, Pages 209-220

  Terrinoni, Alessandro ^a,b   Dell'Arciprete, Roberta ^a   Fornaro, Mara ^a,c   Stella, Manuela ^a   Alberti, Saverio ^a  

^a Istituto Mario Negri Consorzio Mario Negri Sud ^*  (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLIN D1; LUCIFERASE; PROTEIN TROP2; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; ONCOPROTEIN; TUMOR ANTIGEN; TUMOR ASSOCIATED ANTIGEN GA733; TUMOR MARKER; TUMOR-ASSOCIATED ANTIGEN GA733;

ARTICLE; CANCER CELL; CANCER GROWTH; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA SEQUENCE; DNA TRANSFECTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MUTAGENESIS; NORTHERN BLOTTING; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; RIBONUCLEASE PROTECTION ASSAY; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CELL STRAIN 3T3; CELL STRAIN COS1; CELL TRANSFORMATION; CHROMOSOME MAP; DNA TEMPLATE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; L CELL; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PROTO ONCOGENE;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NEOPLASM; BASE SEQUENCE; CELL ADHESION MOLECULES; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; COS CELLS; CYCLIN D1; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-1; HUMANS; L CELLS (CELL LINE); MICE; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS, FUSION; PHYSICAL CHROMOSOME MAPPING; PROMOTER REGIONS (GENETICS); TEMPLATES, GENETIC; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0034743933     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.1137     Document Type: Article

References (50)

1. A single laser method for subtraction of cell autofluorescence in flow cytometry
2. Immuno fluorescence analysis in flow cytometry: Better selection of antibody-labeled cells after fluorescence overcompensation in the red channel
3. Biochemical characterization of Trop-2, a cell surface molecule expressed by human carcinomas: Formal proof that the monoclonal antibodies T16 and MOv-16 recognize Trop-2
4. Cyclin D1 is a nuclear protein required for cell cycle progression in G1
5. Cyclin D1 as a cellular proto-oncogene
6. Expression of cyclin D1 and EMS1 in bladder tumors: Relationship with chromosome 11q13 amplification
7. Expression and amplification of cyclin genes in human breast cancer
8. Bcl-1/cyclin D1 in malignant lymphoma
9. High-efficiency expression gene cloning by flow cytometry
10. A comprehensive set of sequence analysis programs for the vax
11. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
12. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
13. Definition of a consensus binding site for p53
14. Cloning of the mouse Trop2 gene: Conservation of a PIP2-binding sequence in the cytoplasmic domain of Trop-2
15. Compilation of vertebrate-encoded transcription factors
16. Cloning of the gene encoding TROP-2, a cell-surface glycoprotein expressed by human carcinomas
17. Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell
18. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
19. Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth
20. Function of a human cyclin gene as an oncogene
21. Cyclins and cancer
22. Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age
23. Amplification and expression of the human cyclin D gene in esophageal cancer
24. A variant chromosome translocation at 11q13 identifying PRAD1/cyclin D1 as the BCL-1 gene
25. Structural features in eukaryotic mRNAs that modulate the initiation of translation
26. A truncated cyclin D1 gene encodes a stable mRNA in a human breast cancer cell line
27. NF-kappa B: A pleiotropic mediator of inducible and tissue-specific gene control
28. Expression of T-cell-antigen-receptor heterodimers in a lipid-linked form
29. Human trophoblast cell-surface antigens defined by monoclonal antibodies
30. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
31. Isolation of large T antigen-producing mouse cell lines capable of supporting replication of polyomavirus-plasmid recombinants
32. Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle
33. Inactivation of p53 and amplification of cyclin D1 correlate with clinical outcome in head and neck cancer
34. Specific transformation abolishes cyclin D1 fluctuation throughout the cell cycle
35. Translocations, master genes, and differences between the origins of acute and chronic leukemias
36. Expanded range of 11q13 breakpoints with differing patterns of cyclin D1 expression in B-cell malignancies
37. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
38. Rearrangement of CCND1 (BCL1/PRAD1) 3′ untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias
39. The human Trop-2 is a tumor-associated calcium signal transducer
40. PRAD1, a candidate bcl-1 oncogene: Mapping and expression in centrocytic lymphoma
41. Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex
42. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure
43. Gene rearrangement and overexpression of PRAD1 in lymphoid malignancy with t(11;14)(q13;q32) translocation
44. Molecular cloning and characterization of human adenocarcinoma/epithelial cell-surface-antigen-complementary DNA
45. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation
46. Shared regulatory elements in the promoters of MHC class I and class II genes
47. A simple and rapid method for the selection of oligodeoxynucleotide-directed mutants
48. Transcriptional cross talk between NF-kappaB and p53
49. Characterization of a candidate bcl-1 gene