Apolipoprotein E ε4 positive individuals demonstrate delayed olfactory event-related potentials

Neurobiology of Aging

Volumn 22, Issue 3, 2001, Pages 439-447

  Wetter, Spencer ^a   Murphy, Claire ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

^c UCSD MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Dementia; Odor; Olfactory event related potential (OERP); Smell

Indexed keywords

APOLIPOPROTEIN E4; APOLIPOPROTEIN E;

AGED; ALLELE; ANOSMIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EVOKED AUDITORY RESPONSE; EVOKED SOMATOSENSORY RESPONSE; FEMALE; HUMAN; LATENT PERIOD; MALE; PRIORITY JOURNAL; SMELLING; ELECTRODE; EVOKED BRAIN STEM AUDITORY RESPONSE; GENETICS; GENOTYPE; KINETICS; ODOR; PATHOPHYSIOLOGY; PERCEPTIVE THRESHOLD; PHENOTYPE; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; SMELLING DISORDER; STATISTICAL ANALYSIS; STATISTICAL MODEL;

AGED; ALLELES; APOLIPOPROTEINS E; ELECTRODES; ELECTROPHYSIOLOGY; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; GENOTYPE; HUMANS; KINETICS; LOGISTIC MODELS; MALE; MATCHED-PAIR ANALYSIS; ODORS; OLFACTION DISORDERS; PHENOTYPE; SENSITIVITY AND SPECIFICITY; SENSORY THRESHOLDS; SMELL;

EID: 0034743769     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(01)00215-9     Document Type: Article

References (78)

1. Odorant identification testing in the young child
2. ApoE ε4 allele and cognitive decline in patients with Alzheimer's disease
3. Very early changes in olfactory functioning due to Alzheimer's disease and the role of apolipoprotein E in olfaction
4. Episodic memory changes are associated with the APO-E ε4 allele in nondemented older adults
5. Patterns of brain activation in people at risk for Alzheimer's disease
6. Staging of Alzheimer-related cortical destruction
7. Event-related potentials in psychiatry: Differentiating depression and dementia in the elderly
8. P300 from a single-stimulus paradigm: Auditory intensity and tone frequency effects
9. Gene dose of apolipoprotein type 4 allele and the risk of Alzheimer's disease in late onset families
10. The apolipoprotein E ε4 allele and sex-specific risk of Alzheimer's disease
11. Normal aging and odor intensity effects on the olfactory event-related potential
12. Accelerated decline in apolipoprotein E ε4 homozygotes with Alzheimer's disease
13. Early-onset Alzheimer's disease with a presenilin-1 mutation at the site corresponding to the Volga German presenilin-2 mutation
14. Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene
15. Is the P300 component a manifestation of context updating?
16. Presence of both odor identification and detection deficits in Alzheimer's disease
17. Development of the University of Pennsylvania smell identification test: A standardized microencapsulated test of olfactory function
18. The olfactory bulbs in Alzheimer's disease
19. Suggestions for collection and reporting of chemosensory (olfactory) event-related potentials
20. Apolipoprotein E genotype in patients with Alzheimer's disease: Implications for the risk of dementia among relatives
21. Auditory event-related potentials in different types of dementia
22. Mini-mental state
23. Neuropsychological performance and cognitive olfactory event-related brain potentials in young and elderly adults
24. Event-related brain potentials to attended and ignored olfactory and trigeminal stimuli
25. Electrophysiological differences between subtypes of dementia
26. The differential diagnosis of dementia using P3 latency
27. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhA1
28. Odor memory in Alzheimer's disease
29. Second thoughts: Multiple P300s elicited by a single stimulus
30. The epidemiology of dementia and Alzheimer disease
31. Presenilins and Alzheimer's disease
32. Differences in human chemosensory evoked potentials to olfactory and somatosensory chemical stimuli presented to left and right nostrils
33. Apolipoprotein E ε4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease
34. Volumes of hippocampus, amygdala, and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes
35. Human EEG and odor response
36. Chemosensory alteration of information processing
37. Olfactory impairment in children detected by the children's odor identification test
38. Age-related changes in the olfactory event-related potential: Older males benefit from longer inter-stimulus-intervals
39. Olfactory event-related potentials: Older males demonstrate the greatest deficits
40. Olfactory P3 in young and older adults
41. Odor identification as an early marker for Alzheimer's disease: Impact of lexical functioning and detection sensitivity
42. Age-related changes in the density and morphology of plaques and neurofibrillary tangles in Down syndrome brain
43. Apolipoprotein E status is associated with odor identification deficits in nondemented older persons
44. Olfactory thresholds are associated with degree of dementia in Alzheimer's disease
45. Olfactory dysfunction and odor memory in Alzheimer's disease, Huntington's disease and normal aging
46. Olfactory dysfunction in the elderly: Identification of potential precursors
47. Olfactory event-related potentials and aging: Normative data
48. Olfactory-evoked potentials: Assessment of young and elderly, and comparison to psychophysical threshold
49. Age effects on central nervous system activity reflected in the olfactory event-related potential: Evidence for decline in middle age
50. Apolipoprotein E immunoreactivity in cerebral amalyoid deposits and neurofibrillary tangles in Alzheimer's disease
51. Impaired sensory and cognitive olfactory function in questionable Alzheimer's disease
52. The locus for apolipoprotein E (apoE) is linked to the complement component C3 (C3) locus in chromosome 19 in man
53. P300 habituation from auditory single-stimulus and oddball paradigms
54. Latency variability of the components of auditory event-related potentials to infrequent stimuli in aging. Alzheimer-type dementia and depression
55. The nature of the late positive complex within the olfactory event-related potential (OERP)
56. Clinical utility of long latency "cognitive" event-related potentials (P3): The cons
57. Clinical application of the P3 component of event-related potentials. II. Dementia, depression and schizophrenia
58. Apolipoprotein E polymorphism and Alzheimer's disease
59. P300 in the evaluation of aging and dementia
60. P300 clinical utility and control of variability
61. P300 from a single auditory stimulus
62. P300 topography and modality effects from a single-stimulus paradigm
63. 7 Bloom FE. P300 assessment of early Alzheimer's disease
64. P300 and probability: Comparison of oddball and single-stimulus paradigms
65. The distribution of tangles, plaques, and related immunohistochemical markers in healthy aging and Alzheimer's disease
66. Apolipoprotein E ε4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases
67. Apolipoprotein E, memory, and Alzheimer's disease
68. A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein ε4 allele
69. Electrophysiological assessment of mental function in aging and dementia
70. Apolipoprotein E: High-avidity binding to B-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
71. CSF tau is related to apolipoprotein E genotype in early Alzheimer's disease
72. Risk factors for Alzheimer's disease: A collaborative re-analysis of case-control studies
73. Apolipoprotein E typing by one-stage PCR
74. Individuals with Down's syndrome demonstrate abnormal olfactory event-related potentials
75. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome
76. Increased density of olfactory receptor neurons immunoreactive for apolipoprotein E in patients with Alzheimer's disease