Environments of ethidium binding to allosteric DNA: II. Accessibility, mobility and mode of binding

Experimental and Molecular Medicine

Volumn 32, Issue 4, 2000, Pages 204-209

  Suh, Dongchul ^a  

^a CHA University   (South Korea)

Author keywords

Allosteric DNA; Fluorescence energy transfer; Fluorescence polarization; Fluorescence quenching; Mode of binding

Indexed keywords

DNA; LIGAND;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; DNA BINDING; DNA STRUCTURE; ENERGY TRANSFER; FLUORESCENCE; HYBRIDIZATION; METHODOLOGY; POLARIZATION; PROTEIN BINDING;

EID: 0034739832     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2000.33     Document Type: Article

References (19)

1. Barkley, M. D., Thomas, T. J., Maskos, K. and Remers, W. A. (1991) Steady-state fluorescence and molecular-modeling studies of tomaymycin-DNA adducts. Biochemistry 30: 4421-4431
2. Chaires, J. B. (1983) Equilibrium studies on the interaction of daunomycin with deoxyoligonucleotides. Biochemistry 22: 4204-4211
3. Chaires, J. B., Satyanalayana, S., Suh, D., Fokt, I., Przewloka, T. and Priebe, W. (1996) Parsing the free energy of anthracycline antibiotic binding to DNA. Biochemistry 35: 2047-2053
4. Chirico, G., Lunelli, L. and Baldini, G. (1990) Conformation of Intercalated DNA Plasmids Investigated by Circular Dichroism and Dynamic Light Scattering. Biophys. Chem. 38: 201-211
5. Clegg, R. M. (1992) Fluorescence resonance energy transfer and nucleic acids. Meth. In Enzymol. 211: 353-389. Academic Press, N.Y.
6. Eftink, M. R. (1991) in Topics in Fluorescence Spectroscopy (Lakowicz, Ed.) Vol. 2, pp. 53-127, Plenum Press, New York.
7. Hard, T. and Kearns, D. R. (1986) Anisotropic motions in intercalative DNA-dye complexes. J. Phys. Chem. 90: 3437-3444
8. Hard, T. and Kearns, D. R. (1986) Anisotropic overall and internal motions of short DNA fragments. Nucl. A. Res. 14: 3945-3956
9. Kelly, S. O. and Barton, J. K. (1999) Electron transfer between bases in double helical DNA. Science 283: 375-381
10. Lakowicz, J. R. (1983) Principles of Fluorescence Spectro: scopy, Plenum Press, N.Y.
11. LePecq, J.-B. and Paoletti, C. (1967) A fluorescent complex between ethidium bromide and nucleic acids. J. Mol. Biol. 27: 87-106
12. Scaria, P. V. and Shafer R. H. (1991) Binding of ethidium bromide to a DNA triple helix. J. Biol. Chem. 266: 5417-5423
13. Sheardy, R. D. (1988). Preliminary Spectroscopic Characterizations of a Synthetic DNA Oligomer Containing a B-Z Junction at High Salt. Nucleic Acids Res. 16: 1153-1167
14. Suh, D., Sheardy, R. D. and Chaires, J. B. (1991) Unusual Binding of Ethidium to a DNA Containing a B-Z Junction. Biochemistry 30: 8722-8726
15. Suh, D. and Chaires, J. B. (1995) Criteria for the Mode of Binding of DNA Binding Agents. Bioorg. Med Chem. 3: 723-728
16. Suh D., Wilson III, D. M. and Povirk L. F. (1997) 3′-Phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends. Nucleic Acids Res. 25: 2495-2500
17. Suh, D. (1999) Cooperative binding interaction of ethidium with allosteric DNA. Exp. Mol. Med. 31: 151-158.
18. Waring, M. J. (1965) Complex formation between ethidium bromide and nucleic acids. J. Mol. Biol. 13: 269-282
19. Wells, R. D. (1988) Unusual DNA Structures. J. Biol. Chem. 263: 1095-1098