Inhibition of steroid sulphatase activity by tricyclic coumarin sulphamates

Journal of Steroid Biochemistry and Molecular Biology

Volumn 75, Issue 4-5, 2000, Pages 253-258

  Malini, B ^a   Purohit, A ^a   Ganeshapillai, D ^b   Woo, L W L ^b   Potter, B V L ^b   Reed, M J ^a  

^a ST MARY S HOSPITAL   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

Inhibitor; Pharmacophore; Steroid sulphatase activity

Indexed keywords

4 METHYLCOUMARIN 7 O SULFAMATE; 4 OXO 2,3 DIHYDRO 1H CYCLOPENTA [C][1]BENZOPYRAN 7 O SULFAMATE; 6 OXO 7,8,9,10 TETRAHYDRODIBENZO [D,B]PYRAN 3 O SULFAMATE; 6 OXO 7,8,9,10,11,12 HEXAHYDRO CYCLOOCTA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 7,8,9,10,11,12,13,14 OCTAHYDRO CYCLODECA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 7,8,9,10,11,12,13,14,15,16 DECAHYDRO CYCLODODECA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 8,9,10,11 TETRAHYDRO 7H CYCLOHEPTA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 8,9,10,11,12,13 HEXAHYDRO 7H CYCLONONA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 8,9,10,11,12,13,14,15 OCTAHYDRO 7H CYCLOUNDECA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 8,9,10,11,12,13,14,15,16,17 DECAHYDRO 7H CYCLOTRIDECA [C][1]BENZOPYRAN 3 O SULFAMATE; 6 OXO 8,9,10,11,12,13,14,15,16,17,18,19 DODECAHYDRO 7H CYCLOPENTADECA [C][1]BENZOPYRAN 3 O SULFAMATE; COUMARIN DERIVATIVE; ESTRONE SULFATASE; STERYL SULFATASE; SULFATASE; TRICYCLIC COUMARIN SULFAMATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; DOSE RESPONSE; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG POTENTIATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FEMALE; IC 50; LEUKOCYTE; MICROSOME; NONHUMAN; PHARMACOPHORE; RAT;

ANIMALS; ARYLSULFATASES; COUMARINS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FEMALE; LIVER; RATS; RATS, WISTAR; STERYL-SULFATASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034739788     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00178-3     Document Type: Article

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