Identification of an essential backbone amide bond in the folding and stability of a multimeric enzyme

Journal of the American Chemical Society

Volumn 122, Issue 34, 2000, Pages 8105-8111

  Nakhle, Bassam M ^a   Silinski, Peter ^a   Fitzgerald, Michael C ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL ENZYME;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CIRCULAR DICHROISM; ENZYME CONFORMATION; ENZYME STABILITY; GEL PERMEATION CHROMATOGRAPHY; HYDROGEN BOND; MOLECULAR INTERACTION; PROTEIN FOLDING; SYNTHESIS;

EID: 0034734353     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0006090     Document Type: Article

References (23)

1. Smith, M. Angew. Chem., Int. Ed. Engl. 1994, 33, 1214-1221.
2. (a) Muir, T. W.; Kent, S. B. H. Curr. Opin. Biotechnol. 1993, 4, 420-427
3. (b) Lu, W.; Qasim, M. A.; Laskowski, M.; Kent S. B. H. Biochemistry 1997, 36, 673-678.
4. (a) Koh, J. T.; Cornish, V. W.; Schultz, P. G. Biochemistry 1997, 36, 11314-11322.
5. (b) Chapman, E.; Thorson, J. S.; Schultz, P. G. J. Am. Chem. Soc. 1997, 119, 7151-7152.
6. Chen, L. H.; Kenyon, G. L.; Curtin, F.; Harayama, S.; Bembenek, M. E.; Hajipour, G.; Whitman, C. P. J. Biol. Chem. 1992, 267, 17716-17721.
7. Subramanya, H. S.; Roper, D. I.; Dauter, Z.; Dodson, E. J.; Davies, G. J.; Wilson, K. S.; Wigley, D. B. Biochemistry 1996, 35, 792-802.
8. Whitman, C. P.; Aird, B. A.; Gillespie, W. R.; Stolowich, N. J. J. Am. Chem. Soc. 1991, 113, 3154-3162.
9. Whitman, C. P.; Hajipour, G.; Watson, R. J.; Johnson, W. H.; Bembenek, M. E.; Stolwich, N. J. J. Am. Chem. Soc. 1992, 114, 10104-10110.
10. Lian, H.; Whitman, C. P. J. Am. Chem. Soc. 1993, 115, 7978-7984.
11. Fitzgerald, M. C.; Chernushivech, I.; Standing, K. G.; Kent, S. B. H.; Whitman, C. P. J. Am. Chem. Soc. 1995, 117, 11075-11080.
12. Fitzgerald, M. C.; Chernushevich, I.; Standing, K. G.; Whitman, C. P.; Kent, S. B. H. Proc. Natl. Acad. Sci., USA 1996, 93, 6851-6856.
13. Stivers, J. T.; Abeygunawadana, C.; Mildvan, A. S.; Hajipour, G.; Whitman, C. P.; Chen, L. H. Biochemistry 1996, 35, 803-813.
14. Czerwinski, R. M.; Johnson, W. H., Jr.; Whitman, C. P.; Harris, T. K.; Abeygunawardana, C.; Mildvan, A. S. Biochemistry 1997, 36, 14551-14560.
15. Czerwinski, R. M.; Harris, T. K.; Johnson, W. H., Jr.; Legler, P. M.; Stivers, J. T.; Mildvan, A. S.; Whitman, C. P. Biochemistry 1999, 38, 12358-12366.
16. Fitzgerald, M. C.; Czerwinski, R. M.; Whitman, C. P. Unpublished Results.
17. Greenfield, N.; Fasman, G. D. Biochemistry 1969, 8, 4108-4116.
18. Wiberg, K. B.; Laidig, K. E. J. Am. Chem. Soc. 1987, 109, 5935-5943.
19. Arnett, E. M.; Mitchell, E. J.; Murty, T. S. S. R. J. Am. Chem. Soc. 1974, 96, 3875-3891.
20. Jaffe, H. H.; Freedman, L. D.; Doak, G. O. J. Am. Chem. Soc. 1953, 75, 2209-2221.
21. Hill, R. B.; Hong, J.-K.; DeGrado, W. F. J. Am. Chem. Soc. 2000, 122, 746-747.
22. Waddell, W. J. J. Lab. Clin. Med. 1956, 48, 311-314.
23. Schnolzer, M.; Alewood, P.; Jones, A.; Alewood, D.; Kent, S. B. H. Int J. Pept. Protein Res. 1992, 40, 180-193.