The weaver gene has no effect on the generation patterns of mesencephalic dopaminergic neurons

Developmental Brain Research

Volumn 122, Issue 2, 2000, Pages 165-172

  Martí, Joaquín ^a,c   Wills, Katherine V ^a   Ghetti, Bernardino ^b   Bayer, Shirley A ^a  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

3H Thymidine autoradiography; Dopaminergic neuron loss; Interfascicular nucleus; Retrorubral field; Substantia nigra pars compacta; Tyrosine hydroxylase immunohistochemistry; Ventral tegmental area; Weaver mutant mouse

Indexed keywords

DOPAMINE; THYMIDINE; TRITIUM; TYROSINE 3 MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOARCHITECTURE; DEVELOPMENTAL DISORDER; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; GENE; GENE MUTATION; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANIMALS, NEWBORN; CELL COUNT; DOPAMINE; MESENCEPHALON; MICE, NEUROLOGIC MUTANTS; NEURONS; RED NUCLEUS; SUBSTANTIA NIGRA; TEGMENTUM MESENCEPHALI;

ANIMALIA; PLOCEINAE; TRITIUM;

EID: 0034734284     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(00)00070-5     Document Type: Article

References (19)

1. Altman J., Bayer S.A. Development of the brain stem in the rat. V. Thymidine-radiographic study of the time of origin of neurons in the midbrain tegmentum. J. Comp. Neurol. 198:1981;677-716.
2. Bayer S.A., Altman J. Directions in neurogenetic gradients and patterns of anatomical connections in the telencephalon. Prog. Neurobiol. 29:1987;57-106.
3. Bayer S.A., Triarhou L.C., Thomas J.D., Ghetti B. Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice. J. Neurosci. 14:1994;6901-6910.
4. Bayer S.A., Wills K.V., Triarhou L.C., Thomas J.D., Ghetti B. Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants. Exp. Brain Res. 105:1995;200-208.
5. Bayer S.A., Wills K.V., Triarhou L.C., Verina T., Thomas J.D., Ghetti B. Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proc. Natl. Acad. Sci. USA. 92:1995;9137-9140.
6. Bayer S.A., Wills K.V., Triarhou L.C., Ghetti B. Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse. Exp. Brain Res. 105:1995;191-199.
7. Bayer S.A., Wills K.V., Wei J., Feng Y., Dlouhy S.R., Hodes M.E., Verina T., Ghetti B. Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain. Dev. Brain Res. 96:1996;130-137.
8. B. Ghetti, L.C. Triarhou, Degeneration of mesencephalic dopamine neurons in weaver mutant nice, Neurochem. Int. 20 (1992) 305S-307S, Suppl.
9. Gupta M., Felten D.L., Ghetti B. Selective loss of monoaminergic neurons in weaver mutant mice-an immunocytochemical study. Brain Res. 402:1987;379-382.
10. J. Martí, K.V. Wills, B. Ghetti, S.A. Bayer, The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90, Dev. Brain Res. 122 (2000) 173-181 (this issue).
11. Rakic P., Sidman R.L. Sequence of development abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice. J. Comp. Neurol. 152:1973;103-132.
12. Roffler-Tarlov S., Pugatch D., Graybiel A.M. Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. II. High affinity uptake sites for dopamine. J. Neurosci. 10:1990;734-740.
13. Roffler-Tarlov S., Martin B., Graybiel A.M., Kauer J.S. Cell death in the midbrain of the murine mutation weaver. J. Neurosci. 16:1996;1819-1826.
14. Schmidt M.J., Sawyer B.D., Perry K.W., Fuller R.W., Foreman M.M., Ghetti B. Dopamine deficiency in the weaver mutant mouse. J. Neurosci. 2:1982;376-380.
15. Sidman R.L., Angevine J.B., Taber-Pierce E. Atlas of the Mouse Brain and Spinal Cord. 1971;Harvard University Press, Cambridge, MA.
16. Triarhou L.C., Norton J., Ghetti B. Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice. Exp. Brain Res. 70:1988;256-265.
17. Triarhou L.C., Norton J., Ghetti B. Synaptic connectivity of tyrosine hydroxylase immunoreactive nerve terminals in the striatum of normal, heterozygous and homozygous weaver mutant mice. J. Neurocytol. 17:1988;221-232.
18. Verney C., Febvret-Muzerelle A., Gaspar P. Early postnatal changes of the dopaminergic mesencephalic neurons in the weaver mutant mouse. Dev. Brain Res. 89:1995;115-119.
19. Wei J., Dlouhy S.R., Bayer S., Piva R., Verina T., Wang Y., Feng Y., Dupree B., Hodes M.E., Ghetti B. In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice. J. Neuropathol. Exp. Neurol. 56:1997;762-771.