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Volumn 288, Issue 5475, 2000, Pages 2376-2379

Malaria parasite development in a Drosophila model

Author keywords

[No Author keywords available]

Indexed keywords

AEDES AEGYPTI; ARTICLE; DROSOPHILA MELANOGASTER; FEMALE; IMMUNE RESPONSE; IMMUNE SYSTEM; MALARIA; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PLASMODIUM GALLINACEUM; PRIORITY JOURNAL; REPRODUCTION; SPOROZOITE;

EID: 0034733577     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.288.5475.2376     Document Type: Article
Times cited : (87)

References (18)
  • 13
    • 0342497506 scopus 로고    scopus 로고
    • in press
    • Bead injection was shown to block phagocytosis by macrophages with an assay as follows: polystyrene beads (0.2 μm) were injected into a fly 24 hours before a phagocytosis assay. For the phagocytosis assays, bead-treated and untreated flies were injected with fluorescein isothiocyanate (FITC)-labeled E. coli at t = 0. Phagocytosis was monitored by injection of trypan blue into the flies 30 min after E. coli injection. This dye quenched the fluorescence of all extracellular bacteria but not bacteria that had been internalized by macrophages. In non-bead-treated flies, phagocytic cells were found scattered through the body and were concentrated on the dorsal vessel. Bead treatment was found to block all phagocytosis of FITC-labeled E. coli [M. Elrod-Erickson, S. Mishra, D. Schneider, Curr. Biol., in press].
    • Curr. Biol.
    • Elrod-Erickson, M.1    Mishra, S.2    Schneider, D.3
  • 18
    • 0343367051 scopus 로고    scopus 로고
    • note
    • We thank G. Fink, L. Miller, T. Orr Weaver, J. Ribeiro, and S. Sanders for comments on the manuscript. We also thank B. Levin for designing and performing RT-PCR reactions and A. Costero for preparing the mosquito oocyst data. Animals were treated in accordance with institutional guidelines. Supported by the Whitehead Fellows program (D.S.) and the John D. and Catherine T. MacArthur Foundation for M.S.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.