A novel functional estrogen receptor on human sperm membrane interferes with progesterone effects

Molecular and Cellular Endocrinology

Volumn 161, Issue 1-2, 2000, Pages 31-35

  Baldi, Elisabetta ^a   Luconi, Michaela ^a   Muratori, Monica ^a   Forti, Gianni ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Estrogen receptor; Human sperm membrane; Progesterone

Indexed keywords

CALCIUM; ESTRADIOL; ESTROGEN RECEPTOR; PROGESTERONE;

ACROSOME REACTION; CALCIUM CELL LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MEMBRANE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPERM; SPERMATOZOON;

ACROSOME REACTION; CALCIUM SIGNALING; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; HUMANS; MALE; MEMBRANE PROTEINS; PHOSPHORYLATION; PROGESTERONE; RECEPTORS, ESTROGEN; SPERMATOZOA; TYROSINE;

EID: 0034732124     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00220-8     Document Type: Conference Paper

References (24)

1. Baldi E., Luconi M., Bonaccorsi L., Krausz C., Forti G. Human sperm activation during capacitation and acrosome reaction: role of calcium, protein phosphorylation and lipid remodelling pathways. Front. Biosci. 1:1996;d189-d205.
2. Baldi E., Luconi M., Bonaccorsi L., Maggi M., Francavilla S., Gabriele A., Properzi G., Forti G. Non-genomic progesterone receptor on human spermatozoa: biochemical aspects and clinical implications. Steroids. 64:1999;143-148.
3. Batra S., Helm G., Owman C., Sjoberg N.O., Walles B. Female sex steroid concentrations in the ampullary and isthmic regions of the human fallopian tube and their relationship to plasma concentrations during the menstrual cycle. Am. J. Obstet. Gynecol. 136:1980;986-991.
4. 125I]iodohistamine) identifies four protein bands in mouse brain membranes. J. Neurochem. 63:1994;1434-1438.
5. 125I]iodohistamine) in mouse brain membranes. J. Steroid. Biochem. Mol. Biol. 58:1996;89-94.
6. Cheng F.P., Gadella B.M., Voorhout W.F., Fazeli A., Beveres M.M., Colebrander B. Progesterone-induced acrosome reaction in stallion spermatozoa is mediated by a plasma membrane progesterone receptor. Biol. Reprod. 59:1998;733-742.
7. Couse J.F., Korach K.S. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr. Rev. 20:1999;358-417.
8. Frederick J.L., Francis M.M., Macaso T.M., Lobo R.A., Sauer M.V., Paulson R.J. Preovulatory follicular fluid steroid levels in stimulated and unstimulated cycles triggered with human chorionic gonadotropin. Fertil. Steril. 55:1991;44-47.
9. Greene G.L., Sobel N.B., King W.J., Jensen E.V. Immunochemical studies of estrogen receptors. J. Steroid Biochem. 20:1984;51-56.
10. Hernandez-Perez O., Ballesteros L.M., Rosado A. Binding of 17-β-estradiol to the outer surface and nucleus of human spermatozoa. Arch. Androl. 3:1979;23-29.
11. Hyne R.V., Boettcher B. The selective binding of steroids to human spermatozoa. Contraception. 15:1977;163-174.
12. Luconi M., Bonaccorsi L., Maggi M., Pecchioli P., Krausz C., Forti G., Baldi E. Identification and characterization of functional non-genomic progesterone receptors on human sperm membrane. J. Clin. Endocrinol. Metab. 83:1998;877-890.
13. Luconi M., Barni T., Vannelli G.B., Krausz C., Marra F., Benedetti P.A., Evangelista V., Francavilla F., Properzi G., Forti G., Baldi E. Extracellular signal-regulated kinases modulate capacitation of human spermatozoa. Biol. Reprod. 58:1998;1476-1489.
14. erk) in human spermatozoa. Mol. Hum. Reprod. 4:1998;251-258.
15. Luconi M., Muratori M., Forti G., Baldi E. Identification and characterization of a novel functional estrogen receptor on human sperm membrane that interferes with progesterone effects. J. Clin. Endocrinol. Metab. 84:1999;1670-1678.
16. Migliaccio A., Pagano M., Auricchio F. Immediate and transient stimulation of protein tyrosine phosphorylation by estradiol in MCF-7 cells. Oncogene. 8:1993;2183-2191.
17. Monje P., Boland R. Characterization of membrane estrogen binding proteins from rabbit uterus. Mol. Cell. Endocrinol. 147:1999;75-84.
18. Nemere I., Farach-Carson M.C. Membrane receptors for steroid hormones: a case for specific cell surface binding sites for vitamin D metabolites and estrogens. Biochem. Biophys. Res. Commun. 248:1998;443-449.
19. Pappas T.C., Gametchu B., Watson C.S. Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding. FASEB J. 9:1995;404-410.
20. Razandi M., Pedram A., Greene G.L., Levin E.R. Cell membrane and nuclear estrogen receptors (Ers) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Mol. Endocrinol. 13:1999;307-319.
21. Revelli A., Massobrio M., Tesarik J. Non-genomic actions of steroid hormones in reproductive tissue. Endocr. Rev. 19:1998;3-17.
22. Sabeur K., Edwards D.P., Meizel S. Human sperm plasma membrane progesterone receptor(s) and the acrosome reaction. Biol. Reprod. 54:1996;993-1001.
23. Wehling M. Specific non-genomic actions of steroid hormones. Annu. Rev. Physiol. 59:1997;365-393.
24. Weigel N.L. Steroid hormone receptors and their regulation by phosphorylation. Biochem. J. 319:1996;657-667.