Effects of long-term infusion of anorexic concentrations of islet amyloid polypeptide on neurotransmitters and neuropeptides in rat brain

Brain Research

Volumn 887, Issue 2, 2000, Pages 391-398

  Arnelo, Urban ^a   Herrington, Margery K ^a   Theodorsson, Elvar ^b   Adrian, Thomas E ^c   Reidelberger, Roger ^c   Larsson, Jörgen ^a   Marcusson, Jan ^b   Strömmer, Lisa ^a   Ding, Xianzhong ^c   Permert, Johan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Body weight; Brain; Islet amyloid polypeptide; Monoamine; Neuropeptide; Satiety

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; AMYLIN; ANOREXIGENIC AGENT; CHOLECYSTOKININ; NEUROPEPTIDE; NEUROPEPTIDE Y; NEUROTENSIN; NEUROTRANSMITTER; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; FOOD INTAKE; HIPPOCAMPUS; HYPOTHALAMUS; MALE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SATIETY;

3,4-DIHYDROXYPHENYLACETIC ACID; AMYLOID; ANIMALS; ANOREXIA; BIOGENIC MONOAMINES; BLOOD GLUCOSE; BRAIN; CHOLECYSTOKININ; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMOVANILLIC ACID; HYDROXYINDOLEACETIC ACID; INFUSIONS, PARENTERAL; INSULIN; MALE; METHOXYHYDROXYPHENYLGLYCOL; NEUROPEPTIDE Y; NEUROPEPTIDES; NEUROTENSIN; NOREPINEPHRINE; RATS; RATS, WISTAR; SEROTONIN;

EID: 0034731639     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)03070-5     Document Type: Article

References (42)

1. Phentolamine reverses NPY-induced inhibition of insulin secretion in isolated rat islets
2. Effects of acute and chronic infusion of islet amyloid polypeptide on food intake in rats
3. Chronic infusion of islet amyloid polypeptide causes anorexia in rats
4. Chronic low dose islet amyloid polypeptide infusion reduces food intake, but does not influence glucose metabolism, in unrestrained conscious rats: Studies using a novel aortic catheterization technique
5. Sufficiency of postprandial plasma levels of islet amyloid polypeptide for suppression of feeding in rats
6. Syntheses, structures and anorectic effects of human and rat amylin
7. Differential permeability of the blood-brain barrier to two pancreatic peptides: Insulin and amylin
8. Brain regions where cholecystokinin suppresses feeding in rats
9. In vivo central actions of rat amylin
10. Effects of meal ingestion on plasma amylin concentration in NIDDM and non-diabetic humans
11. Anorexia following the systemic injection of amylin
12. Anorexia following the intrahypothalamic administration of amylin
13. Neurotransmitter alterations associated with feeding and satiety
14. Biological actions of cholecystokinin
15. Nutritional deficiency, starvation, and tissue antioxidant status
16. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
17. Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats
18. Postnatal development of circulating cholecystokinin and secretin, pancreatic growth, and exocrine function in guinea pigs
19. IAPP as a regulator of glucose homeostasis and pancreatic hormone secretion
20. Activation of the adrenocortical axis by surgical stress: Involvement of central norepinephrine and interleukin-1
21. Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro
22. Different influence of CGRP (8-37), an amylin and CGRP antagonist, on the anorectic effects of cholecystokinin and bombesin in diabetic and normal rats
23. Amylin reduces food intake more potently than calcitonin gene-related peptide (CGRP) when injected into the lateral brain ventricle in rats
24. Lesion of the area postrema/nucleus of the solitary tract (AP/NTS) attenuates the anorectic effects of amylin and calcitonin gene-related peptide (CGRP) in rats
25. Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice
26. Amylin decreases food intake in mice
27. Modulation of food intake by peripherally administered amylin
28. Amylin and food intake in mice: Effects on motivation to eat and mechanism of action
29. Effects of mesocortical dopaminergic lesions on stress-induced changes in monoamine metabolism in the discrete brain regions of rats
30. Islet amyloid polypeptide in patients with pancreatic cancer patients and diabetes
31. Amylin: A novel action in the brain to reduce body weight
32. Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus
33. Distribution of cells containing mRNA encoding cholecystokinin in the rat central nervous system
34. Ventral mesencephalic neurons containing both cholecystokinin- and tyrosine hydroxylase-like immunoreactivities project to forbrain regions
35. In vitro autoradiographic localization of amylin binding sites in rat brain
36. Islet amyloid polypeptide amide causes peripheral insulin resistance in vivo in dogs
37. Concurrent analysis of neuropeptides and biogenic amines in brain tissue of rats treated with electroconvulsive stimuli
38. Radioimmunoassay for neuropeptide Y (NPY): Chromatographic characterization of immunoreactivity in plasma and tissue extracts
39. Characterization of human plasma neurotensin-like immunoreactivity after fat ingestion
40. A novel peptide in the calcitonin gene related family as an amyloid fibril protein in the endocrine pancreas
41. Hypocalcemic actions of amylin amide in humans
42. Gastric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin