Diversity of the p70 killer cell inhibitory receptor (KIR3DL) family members in a single individual

Molecules and Cells

Volumn 10, Issue 1, 2000, Pages 54-60

  Kwon, Daeho ^a   Chwae, Yong Joon ^a   Choi, In Hong ^a   Park, Jeon Han ^a   Kim, Jongsun ^a   Kim, Se Jong ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Alternative Splicing; NK cells; p70 KIR; Polymorphism; Receptor Repertoire

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN RECEPTOR; ISOPROTEIN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; CYTOLOGY; DNA SEQUENCE; GENETIC VARIABILITY; GENETICS; HUMAN; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MONONUCLEAR CELL; MULTIGENE FAMILY; NATURAL KILLER CELL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTEIN ISOFORMS; RECEPTORS, IMMUNOLOGIC; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; VARIATION (GENETICS);

EID: 0034728278     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-000-0054-0     Document Type: Article

References (34)

1. Binstadt, B. A., Brumbaugh, K. M., Dick, C. J., Scharenberg, A. M., Williams, B. L., Colonna, M., Lanier, L. L., Kinet, J. P., Abraham, R. T., and Leibson, P. J. (1996) Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity 5, 629-638.
2. Burshtyn, D. N., Scharenberg, A. M., Wagtman, N., Rajagopalan, S., Berrada, K., Yi, T., Kinet, J. P., and Long, E. O. (1996) Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 4, 77-85.
3. + lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory functions. Blood 87, 2369-2375.
4. Campbell, K. S., Dessing, M., Lopez-Botet, M., Cella, M., and Colonna, M. (1996) Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J. Exp. Med. 184, 93-100.
5. Chwae, Y.-J., Cho, S. E., Kim, S. J., and Kim, J. (1999) Diversity of the repertoire of p58 killer cell inhibitory receptors in a single individual. Immunol. Lett. 68, 267-274.
6. Colonna, M. and Samaridis, J. (1995) Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268, 405-408.
7. D'Andrea, A., Chang, C., Franz-Bacon, K., McClanahan, T., Phillips, J. H., and Lanier, L. L. (1995) Molecular cloning of NKB1: a natural killer cell receptor for HLA-B allotypes. J. Immunol. 155, 2306-2310.
8. Döhring, C., Samaridis, J., and Colona, M. (1996) Alternatively spliced forms of human killer inhibitory receptors. Immunogenetics 44, 227-230.
9. Fan, Q. R., Garboczi, D. N., Winter, C. C., Wagtmann, N., Long, E. O., and Wiley, D. C. (1996) Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex, molecule. Proc. Natl. Acad. Sci. USA 93, 7178-7183.
10. Fry, A. M., Lanier, L. L., and Weiss, A. (1996) Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein phosphatase 1C. J. Exp. Med. 184, 295-300.
11. Kim, J., Chwae, Y. J., Kim, M. Y., Choi, I. H., Park, J. H., and Kim, S. J. (1997) Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors. J. Immunol. 159, 3875-3882.
12. Kim, J., van Tienhoven, E., Garboczi, D. N., Utz, U., Kim, M. Y., and Wiley, D. C. (1996) Specific binding of a soluble recombinant β-chain T-cell antigen receptor to Toxic Shock Syndrome Toxin-1, a superantigen. Mol. Cells 6, 590-596.
13. Lanier, L. L. (1997) NK cells: from no receptor to too many. Immunity 6, 371-378.
14. Lanier, L. L. and Phillips, J. H. (1996) Inhibitory MHC class 1 receptors on NK cells and T cells. Immunol. Today 17, 86-91.
15. Mingari, M. C., Vitale, C., Cambiaggi, A., Schiavetti, F., Melioli, G., Ferrini, S., and Poggi, A. (1995) Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production. Int. Immunol. 7, 697-703.
16. Moretta, A., Biassoni, R., Bottino, C., Pende, D., Vitale, M., Poggi, A., Mingari, M. C., and Moretta, L. (1997) Major histocompatibility complex class-I specific receptors on human natural killer and T lymphocytes. Immunol. Rev. 155, 105-117.
17. Mount, S. M. (1982) A catalogue of splice junction sequences. Nucleic Acids Res, 10, 459-472.
18. Parham, P. (1997) NK cells. MHC class I antigens and missing self. Immunol. Rev. 155, 5-221.
19. Parham, P., Adams, E. J., and Arnett, K. L. (1995) The origins of HLA-A, B, C polymorphism. Immunol. Rev. 143, 141-180.
20. Pende, D., Biassoni, R., Cantoni, C., Verdiani, S., Falco, M., Di Donato, C., Accame, L., Bottino, C., Moretta, A., and Moretta, L. (1996) The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulfide-linked dimer. J. Exp. Med. 184, 505-518.
21. Phillips, J. H., Gumperz, J. E., Parham, P., and Lanier, L. L. (1995) Superantigen-dependent, cell mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science 268, 403-405.
22. Rojo, S., Wagtmann, N., and Long, E. O. (1997) Binding of a soluble p70 killer cell inhibitory receptor to HLA-B*5101: requirement for all three p70 immunoglobulin domains. Eur. J. Immunol. 27, 568-571.
23. Selvakumar, A., Steffens, U., and Dupont, B. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155, 183-196.
24. Shilling, H. G., Lienert-Weidenbach, K., Valiante, N. M., Uhrberg, M., and Parham, P. (1998) Evidence for recombination as a mechanism for KIR diversification. Immunogenetics 48, 413-416.
25. Sodeoka, M., Larson, C. J., Chen, L., LeClair, K. P., and Verdine, G. L. (1993) A multifunctional plasmid for protein expression by ECPCR: overproduction of the p50 subunit of NF-KB. Bioorg. Med. Chem. Lett. 3,1089-1093.
26. Steffens, U., Vyas, Y., Dupont, B., Selvakumar, A. (1998) Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptor (KIR). Tissue Antigens 51, 398-413.
27. Suto, Y., Maenaka, K., Yabe, T., Hirai, M., Tokunaga, K., Tadok, K., and Juji, T. (1996) Chromosomal localization of the human killer cell class I receptor family genes on 19q13.4 by fluorescence hybridization. Genomics 35, 270-272.
28. Suto, Y., Ishikawa, Y., Kasahara, M., Kasai, F., Yabe, T., Akaza, T., and Juji, T. (1998) Gene arrangement of the killer inhibitory receptor family on human chromosome 19q13.4 detected by fiber-FISH. Immunogenetics 48, 235-241.
29. Valiante, N. M., Lienert, K., Shilling, H. G., Smits, B. J., and Parham, P. (1997) Killer cell receptors: keeping pace with MHC class I evolution. Immunol. Rev. 155, 155-164.
30. Vitale, M., Sivori, S., Pende, D., Moretta, L., and Moretta, A. (1995) Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogenetic target cells. Proc. Natl. Acad. Sci. USA 92, 3536-3540.
31. Vyas, Y., Selvakumar, A., Steffens, U., and Dupont, B. (1998) Multiple transcripts of the killer cell immunoglobulin-like receptor family, KIR3DL1 (NKB1), are expressed by natural killer cells of a single individual. Tissue Antigens 52, 510-519.
32. Wagtmann, N., Biassoni, R., Cantoni, C., Verdani, S., Manati, M. S., Vitale, M., Cottino, C., Moretta, L., Moretta, A., and Long, E. O. (1995a) Molecular clones of the p58 NK call receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2, 439-449.
33. Wagtmann, N., Rajagopalan, S., Winter, C. C., Peruzzi, M., and Long, E. O. (1995b) Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3, 801-809.
34. Winter, C. and Long, E. O. (1997) A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes. J. Immunol. 158, 4026-4028.