Cytomegalovirus infection of vascular cells induces expression of pro- inflammatory adhesion molecules by paracrine action of secreted interleukin- 1β

Transplantation

Volumn 69, Issue 6, 2000, Pages 1160-1168

  Dengler, Thomas J ^a,b   Raftery, Martin J ^a   Werle, Martina ^a   Zimmermann, Rainer ^a   Schönrich, Günther ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; GANCICLOVIR; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANTIVIRAL ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CYTOMEGALOVIRUS INFECTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATORY CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SUPERNATANT; UMBILICAL VEIN; VASCULAR SMOOTH MUSCLE; VIRUS INACTIVATION; VIRUS REPLICATION;

EID: 0034719876     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200003270-00022     Document Type: Article

References (47)

1. Sindre H, Tjoonnfjord GE, Rollag H, et al. Human cytomegalovirus suppression of and latency in early hematopoietic progenitor cells. Blood 1996; 88 (12): 4526.
2. Fish KN, Stenglein SG, Ibanez C, Nelson JA. Cytomegalovirus persistence in macrophages and endothelial cells. Scand J Infect Dis Suppl 1995; 99: 34.
3. Koskinen P, Lemstrom K, Bruning H, Daemen M, Bruggeman C, Hayry P. Cytomegalovirus infection induces vascular wall inflammation and doubles arteriosclerotic changes in rat cardiac allografts. Transplant Proc 1995; 27 (1): 574.
4. Koskinen PK, Nieminen MS, Krogerus LA, et al. Cytomegalovirus infection and accelerated cardiac allograft vasculopathy in huer man cardiac allografts. J Heart Lung Transplant 1993; 12 (5): 724.
5. Lemstrom K, Koskinen P, Krogerus L, Daemen M, Bruggeman C, Hayry P. Cytomegalovirus antigen expression, endothelial cell proliferation, and intimai thickening in rat cardiac allografts after cytomegalovirus infection. Circulation 1995; 92 (9): 2594.
6. Wu TC, Hruban RH, Ambinder RF, et al. Demonstration of cytomegalovirus nucleic acids in the coronary arteries of transplanted hearts. Am J Pathol 1992; 140 (3): 739.
7. Lautenschlager I, Hockerstedt K, Jalanko H, et al. Persistent cytomegalovirus in liver allografts with chronic rejection. Hepatology 1997; 25 (1): 190.
8. Kroshus TJ, Kshettry VR, Savik K, John R, Hertz MI, Bolman RM 3rd. Risk factors for the development of bronchiolitis obliterans syndrome after lung transplantation. J Thorac Cardiovasc Surg 1997; 114 (2): 195.
9. Keenan RJ, Lega ME, Dummer JS, et al. Cytomegalovirus serologic status and postoperative infection correlated with risk of developing chronic rejection after pulmonary transplantation. Transplantation 1991; 51 (2): 433.
10. Almond PS, Matas A, Gillingham K, et al. Risk factors for chronic rejection in renal allograft recipients. Transplantation 1993; 55 (4): 752.
11. Hofmann GO, Schneeberger H, Land W. Risk factors for chronic transplant failure after kidney transplantation. Transplant Proc 1995; 27 (3): 2031.
12. Dummer S, Lee A, Breinig MK, Kormos R, Ho M, Griffith B. Investigation of cytomegalovirus infection as a risk factor for coronary atherosclerosis in the explanted hearts of patients undergoing heart transplantation. J Med Virol 1994; 44 (3): 305.
13. Speir E, Modali R, Huang ES, et al. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 1994; 265 (5170): 391.
14. Melnick JL, Hu C, Burek J, Adam E, DeBakey ME. Cytomegalovirus DNA in arterial walls of patients with atherosclerosis. J Med Virol 1994; 42 (2): 170.
15. Blum A, Giladi M, Weinberg M, et al. High anti-cytomegalovirus (CMV) IgG antibody titer is associated with coronary artery disease and may predict post-coronary balloon angioplasty restenosis. Am J Cardiol 1998; 81 (7): 866.
16. Libby P, Egan D, Skarlatos S. Roles of infectious agents in atherosclerosis and restenosis: an assessment of the evidence and need for future research. Circulation 1997; 96 (11): 4095.
17. Zhou YF, Leon MB, Waclawiw MA, et al. Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy. N Engl J Med 1996; 335 (9): 624.
18. Bartels C, Maass M, Bein G, et al. Detection of Chlamydia pneumoniae but not cytomegalovirus in occluded saphenous vein coronary artery bypass grafts. Circulation 1999; 99 (7): 879.
19. Gulizia JM, Kandolf R, Kendall TJ, et al. Infrequency of cytomegalovirus genome in coronary arteriopathy of human heart allografts. Am J Pathol 1995; 147 (2): 461.
20. Tanaka K, Zou JP, Takeda K, et al. Effects of human cytomegalovirus immediate-early proteins on p53-mediated apoptosis in coronary artery smooth muscle cells. Circulation 1999; 99 (13): 1656.
21. Lemstrom K, Koskinen P, Bruning H, Bruggeman C, Aho P, Hayry P. Cytomegalovirus infection accelerates mRNA expression of several smooth muscle cell growth factors in the allograft vascular wall. Transplant Proc 1995; 27 (1): 566.
22. Lautenschlager I, Hockerstedt K, Taskinen E, von Willebrand E. Expression of adhesion molecules and their ligands in liver allografts during cytomegalovirus (CMV) infection and acute rejection. Transplant Int 1996; 9 (1): S213.
23. Steinhoff G, You XM, Steinmuller C, et al. Induction of endothelial adhesion molecules by rat cytomegalovirus in allogeneic lung transplantation in the rat. Scand J Infect Dis Suppl 1995; 99: 58.
24. Shahgasempour S, Woodroffe SB, Garnett HM. Alterations in the expression of ELAm-1, ICAm-1 and VCAm-1 after in vitro infection of endothelial cells with a clinical isolate of human cytomegalovirus. Microbiol Immunol 1997; 41 (2): 121.
25. Span AH, Mullers W, Miltenburg AM, Bruggeman CA. Cytomegalovirus induced PMN adherence in relation to an ELAm-1 antigen present on infected endothelial cell monolayers. Immunology 1991; 72 (3): 355.
26. Allen MD, King C, MacDonald TO, Himes V. VCAM-1 and E-selectin expression during cytomegalovirus infection in post-transplant myocardial biopsies. Clin Transplant 1996; 10 (6 Pt 1); 528.
27. Koskinen PK. The association of the induction of vascular cell adhesion molecule-1 with cytomegalovirus antigenemia in human heart allografts. Transplantation 1993; 56 (5): 1103.
28. Burns LJ, Pooley JC, Walsh DJ, Vercellotti GM, Weber ML, Kovacs A. Intercellular adhesion molecule-1 expression in endothelial cells is activated by cytomegalovirus immediate early proteins. Transplantation 1999; 67 (1): 137.
29. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52 (11): 2745.
30. Woodroffe SB, Hamilton J, Garnett HM. Comparison of the infectivity of the laboratory strain AD169 and a clinical isolate of human cytomegalovirus to human smooth muscle cells. J Virol Methods 1997; 63 (1-2): 181.
31. Murayama T, Ohara Y, Obuchi M, et al. Human cytomegalovirus induces interleukin-8 production by a human monocytic cell line, THP-1, through acting concurrently on AP-1- and NF- kappaB-binding sites of the interleukin-8 gene. J Virol 1997; 71 (7): 5692.
32. Enari M, Hug H, Nagata S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 1995; 375 (6526): 78.
33. Grattan MT, Moreno-Cabral CE, Starnes VA, Oyer PE, Stinson EB, Shumway NE. Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis. JAMA 1989; 261 (24): 3561.
34. Skowronski EW, Mendoza A, Smith SC Jr, Jaski BE. Detection of cytomegalovirus in paraffin-embedded postmortem coronary artery specimens of heart transplant recipients by the polymerase chain reaction: implications of cytomegalovirus association with graft atherosclerosis. J Heart Lung Transplant 1993; 12 (5): 717.
35. Hendrix MG, Salimans MM, van Boven CP, Bruggeman CA. High prevalence of latently present cytomegalovirus in arterial walls of patients suffering from grade III atherosclerosis. Am J Pathol 1990; 136 (1): 23.
36. Carvalho D, Savage CO, Black CM, Pearson JD. IgG antiendothelial cell autoantibodies from scleroderma patients induce leukocyte adhesion to human vascular endothelial cells in vitro. Induction of adhesion molecule expression and involvement of endothelium-derived cytokines. J Clin Invest 1996; 97 (1): 111.
37. Yurochko AD, Huang ES. Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression. J Immunol 1999; 162 (8): 4806.
38. Iwamoto GK, Monick MM, Clark BD, Auron PE, Stinski MF, Hunninghake GW. Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus. J Clin Invest 1990; 85 (6): 1853.
39. Iwamoto GK, Konicek SA. Cytomegalovirus immediate early genes upregulate interleukin-6 gene expression. J Investig Med 1997; 45 (4): 175.
40. Peters M, Jacobs S, Ehlers M, et al. The function of the soluble interleukin 6 (IL- 6) receptor in vivo: sensitization of human soluble IL- 6 receptor transgenic mice towards IL- 6 and prolongation of the plasma half-life of IL- 6. J Exp Med 1996; 183 (4): 1399.
41. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF- kappa B and cytokine-inducible enhancers. FASEB J 1995; 9 (10): 899.
42. Kavita U, Mizel SB. Differential sensitivity of interleukin-1 alpha and -beta precursor proteins to cleavage by calpain, a calcium-dependent protease. J Biol Chem 1995; 270 (46): 27758.
43. Pober JS, Lapierre LA, Stolpen AH, et al. Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. J Immunol 1987; 138 (10): 3319.
44. Grundy JE, Downes KL. Up-regulation of LFA-3 and ICAm-1 on the surface of fibroblasts infected with cytomegalovirus. Immunology 1993; 78 (3): 405.
45. Devergne O, Peuchmaur M, Humbert M, et al. In vivo expression of IL-1 beta and IL- 6 genes during viral infections in human. Eur Cytokine Network 1991; 2(3): 183.
46. Miller SJ, Hoggat AM, Faulk WP. Heparin regulates ICAM-1 expression in human endothelial cells: an example of non-cytokine-mediated endothelial activation. Thromb Haemost 1998; 80 (3): 481.
47. Minter AJ, Keoshkerian E, Chesterman CN, Dawes J Fibroblast growth factor and heparin protect endothelial cells from the effects of interleukin 1. J Cell Physiol 1996; 167 (2): 229.