Human papilloma virus and development of cervical carcinoma: The concept of carcinogenesis;Humaan papillomavirus en het ontstaan van baarmoederhalskanker: Concept van carcinogenese

Nederlands Tijdschrift voor Geneeskunde

Volumn 144, Issue 35, 2000, Pages 1671-1674

  Walboomers, J M M ^a   Meijer, C J L M ^a   Steenbergen, R D M ^a   Van Duin, M ^a   Helmerhorst, Th J M ^a   Snijders, P J F ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARCINOGENESIS; HUMAN; MALIGNANT TRANSFORMATION; RISK FACTOR; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX EPITHELIUM; VIRUS ONCOGENE; WART VIRUS;

CELL TRANSFORMATION, NEOPLASTIC; CELL TRANSFORMATION, VIRAL; CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; HUMANS; MODELS, BIOLOGICAL; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RISK FACTORS; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS;

EID: 0034718402     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions
2. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
3. Molecular pathogenesis of cancer of the cervix and its causation by specific human papillomavirus types
4. Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes
5. Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: Activation of telomerase and allele losses at 3p, 10p, 11q and/or 18q
6. Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes
7. Viral E6-E7 transcription in the basal layer of organotypic cultures without apparent p21cipI protein precedes immortalization of human papillomavirus type 16- and 18-transfected human keratinocytes
8. Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: Strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papilloma-virus DNA
9. Genetic alterations during the progression of squamous cell carcinomas of the uterine cervix