Cis element 'decoy' against the upstream promoter of the human estrogen receptor gene

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1492, Issue 2-3, 2000, Pages 560-567

  Penolazzi, Letizia ^a   Lambertini, Elisabetta ^a   Aguiari, Gianluca ^a   Del Senno, Laura ^a   Piva, Roberta ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Breast cancer; Decoy; Estrogen receptor; Gene expression; Promoter; Silencing element

Indexed keywords

DOUBLE STRANDED DNA; ESTROGEN RECEPTOR; LUCIFERASE; MESSENGER RNA; TRANSCRIPTION FACTOR;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; SOUTHERN BLOTTING; WESTERN BLOTTING;

BASE SEQUENCE; DNA; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; K562 CELLS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECEPTORS, ESTROGEN; TUMOR CELLS, CULTURED;

EID: 0034710320     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(00)00145-7     Document Type: Article

References (45)

1. Ciocca D.R., Vargas Roig L.M. Estrogen receptors in human nontarget tissues: biological and clinical implications. Endocr. Rev. 16:1995;35-53.
2. M.E. Lippman, R.B. Dickson, Regulation of normal and malignant breast epithelial proliferation, in: Growth Regulation of Cancer II, Vol. 115, Liss, Washington, DC, 1990, pp. 127-172.
3. J.R. Harris, S. Hellman, I.C. Henderson, D.W. Kinne (Eds.), Breast Disease, Lippincott, Philadelphia, PA, 1991.
4. Henderson B.E., Ross R., Bernstein L. Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res. 48:1988;246-253.
5. Katzenellebogen B.S. Antiestrogen resistance: mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy. J. Natl. Cancer Inst. 83:1991;1434-1435.
6. Knight W.A., Livingston R.B., Gregory E.J., McGuire W.L. Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res. 37:1977;4669-4671.
7. Piva R., Bianchi N., Aguiari G.L., Gambari R., del Senno L. Sequencing of an RNA transcript of the human estrogen receptor gene: evidence for a new transcriptional event. J. Steroid Biochem. Mol. Biol. 46:1993;531-538.
8. Keaveney M., Klug J., Gannon F. Sequence analysis of the 5′ flanking region of the human estrogen receptor gene, DNA Sequence-J. DNA Sequencing Mapp. 2:1992;347-358.
9. DeConinck E.C., McPherson L.A., Weigel R.J. Transcriptional regulation of estrogen receptor in breast carcinomas. Mol. Cell. Biol. 15:1995;2191-2196.
10. Grandien K. Determination of transcription start sites in the human estrogen receptor gene and identification of a novel, tissue-specific, estrogen receptor mRNA isoform. Mol. Cell. Endocrinol. 116:1996;207-212.
11. Flouriot G., Griffin C., Kenealy M., Sonntag-Buck V., Gannon F. Differentially expressed mRNA isoforms of the human estrogen receptor-α gene are generated by alternative splicing and promoter usage. Mol. Endocrinol. 12:1998;1938-1954.
12. Thompson D.A., McPherson L.A., Carmeci C., deConinck E.C., Weigel R.J. Identification of two estrogen receptor transcripts with novel 5′ exons isolated from a MCF7 cDNA library. J. Steroid Biochem. Mol. Biol. 62:1997;143-153.
13. Donaghue C., Westley B.R., May F.E.B. Selective promoter usage of the human estrogen receptor - α gene and its regulation by estrogen. Mol. Endocrinol. 13:1999;1934-1950.
14. Green S., Walter P., Kumar V., Krust A., Bonert J., Argos P., Chambon P. Human estrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 320:1986;134-139.
15. McPherson L.A., Baichwal V.R., Weigel R.J. Identification of ERF-1 as a member of the AP2 transcription factor family. Proc. Natl. Acad. Sci. USA. 94:1997;4342-4347.
16. Tang Z., Treilleux I., Brown M. A transcriptional enhancer required for the differential expression of the human estrogen receptor in breast cancer. Mol. Cell. Biol. 17:1997;1274-1280.
17. Cohn C.S., Sullivan J.A., Kiefer T., Hill S.M. Identification of an enhancer element in the estrogen receptor upstream region: implications for the regulation of ER transcription in breast cancer. Mol. Cell. Endocrinol. 158:1999;25-36.
18. Penolazzi L., Lambertini E., Aguiari G.L., del Senno L., Piva R. Modulation of estrogen receptor gene expression in human MCF7 breast cancer cells: a decoy strategy with specific PCR-generated DNA fragments. Breast Cancer Res. Treat. 49:1998;227-235.
19. Morishita R., Sugimoto T., Aoki M., Kida I., Tomita N., Moriguchi A., Maeda K., Sawa Y., Kaneda Y., Higaki J., Ogihara T. In vivo transfection of cis element 'decoy' against nuclear factor-κB binding site prevents myocardial infarction. Nat. Med. 3:1997;894-899.
20. Morishita R., Higaki J., Tomita N., Aoki M., Moriguchi A., Tamura K., Murakami K., Kaneda Y., Ogihara T. Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation. Hypertension. 27:1996;502-507.
21. Morishita R., Gibbons G.H., Masatsugu H., Ellison K.E., Nakajima M., Zhang L., Kaneda Y., Ogihara T., Dzau V.J. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc. Natl. Acad. Sci. USA. 92:1995;5855-5859.
22. Tanaka H., Vickart P., Bertrand J.R., Rayner B., Morvan F., Imbach J.L., Paulin D., Malvy C. Sequence-specific interaction of α·β-anomeric double-stranded DNA with the p50 subunit of NFkB: application to the decoy approach. Nucleic Acids Res. 22:1994;3069-3074.
23. Sharma H.W., Perez J.R., Higgins-Sochaski K., Hsiao R., Narayanan R. Transcription factor decoy approach to decipher the role of NF-kappa B in oncogenesis. Anticancer Res. 16:1996;61-69.
24. Lee S.W., Gallardo H.F., Gilboa E., Smith C. Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain. J. Virol. 68:1994;8254-8264.
25. Yamashita J., Yoshimasa T., Arai H., Hiraoka J., Takaya K., Miyamoto Y., Ogawa Y., Itoh H., Nakao K. Identification of cis-elements of the human endothelin-A receptor gene and inhibition of the gene expression by the decoy strategy. J. Biol. Chem. 273:1998;15993-15999.
26. Clusel C., Meguenni S., Elias I., Vassuer M., Blumenfeld M. Inhibition of HSV-1 proliferation by decoy phosphodiester oligonucleotides containing ICP4 recognition sequences. Gene Expr. 4:1995;301-309.
27. Penolazzi L., Facciolo M.C., Aguiari G.L., del Senno L., Piva R. Direct transfection of PCR-generated DNA fragments into mammalian cells employing ethidium bromide indicator and ultrafiltration. Anal. Biochem. 248:1997;190-193.
28. Pfeffer U., Fecarotta E., Vidali G. Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells. Cancer Res. 55:1995;2158-2165.
29. Cortesi R., Esposito E., Menegatti E., Gambari R., Nastruzzi C. Effect of cationic liposome composition on in vitro cytotoxicity and protective effect on carried DNA. Int. J. Pharm. 139:1996;69-78.
30. Ogbourne S., Antalis T.M. Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes. Biochem. J. 331:1998;1-14.
31. Goto K., Heymont J.L., Kleinnulend J., Kronenberg H.M., Demay M.B. Identification of an osteoblastic silencer element in the first intron of the rat osteocalcin gene. Biochemistry. 35:1996;11005-11011.
32. Donda A., Schulz M., Burki K., Delibero G., Uematsu Y. Identification and characterization of a human CD4 silencer. Eur. J. Immunol. 26:1996;493-500.
33. Ma J., Saito H., Oka T., Vijav I.K. Negative regulatory element involved in the hormonal regulation of GlcNAc-1-P transferase gene in mouse mammary gland. J. Biol. Chem. 271:1996;11197-11203.
34. Antalis T.M., Costelloe E., Muddiman J., Ogbourne S., Donnan K. Regulation of the plasminogen activator inhibitor type-2 gene in monocytes localization of an upstream transcriptional silencer. Blood. 88:1996;3686-3697.
35. Williams T.M., Moolten D., Burlein J., Romano J., Bhaerman R., Godillot A., Mellon M., Rauscher F.J.D., Kant J.A. Identification of a zinc-finger protein that inhibits IL-2 gene expression. Science. 254:1991;1791-1794.
36. Steinmetzer K., Brantl S. Plasmid pIP501 encoded transcriptional repressor CopR binds asymmetrically at two consecutive major grooves of the DNA. J. Mol. Biol. 269:1997;684-693.
37. Murasawa S., Matsubara H., Mori Y., Kijima K., Maruyama K., Inada M. Identification of a negative cis-regulatory element and trans-acting protein that inhibit transcription of the angiotensin II type 1a receptor gene. J. Biol. Chem. 270:1995;24282-24286.
38. Imler J.L., Lemaire C., Wasylyk C., Wasylyk B. Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer. Mol. Cell. Biol. 7:1987;2558-2567.
39. Weissman J.D., Singer D.S. A complex regulatory DNA element associated with a major histocompatibility complex class I gene consists of both a silencer and an enhancer. Mol. Cell. Biol. 11:1991;4217-4227.
40. Zhang Z.X., Kumar V., Rivera R.T., Chisholm J., Biswas D.K. Cis-acting negative regulatory element of prolactin gene. J. Biol. Chem. 265:1990;4785-4788.
41. Pierce J.W., Gifford A.M., Baltimore D. Silencing of the expression of the immunoglobulin kappa gene in non-B cells. Mol. Cell. Biol. 11:1991;1431-1437.
42. Lee W., Mitchell P., Tijan R. Purified transcription factor Ap-1 interacts with TPA-inducible enhancer elements. Cell. 49:1987;741-752.
43. Pham T.A., Hwung Y.P., Santiso-Mere D., McDonnel D.P., O'Malley B.W. Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Mol. Endocrinol. 6:1992;1043-1050.
44. Bianchi N., Passadore M., Feriotto G., Mischiati C., Gambari R., Piva R. Alteration of the expression of human estrogen receptor gene by distamycin. J. Steroid Biochem. Mol. Biol. 54:1995;211-215.
45. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489.