Isolation and structural determination of enfumafungin, a triterpene glycoside antifungal agent that is a specific inhibitor of glucan synthesis

Journal of the American Chemical Society

Volumn 122, Issue 20, 2000, Pages 4882-4886

  Schwartz, Robert E ^a   Smith, Scott K ^a   Onishi, Janet C ^a   Meinz, Maria ^a   Kurtz, Myra ^a   Giacobbe, Robert A ^a   Wilson, Kenneth E ^a   Liesch, Jerrold ^a   Zink, Deborah ^a   Horn, Wendy ^a   Morris, Sandra ^a   Cabello, Angeles ^b   Vicente, Francisca ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPOFUNGIN; ENFUMAFUNGIN; GLUCAN SYNTHASE; GLYCOSIDE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIFUNGAL ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

EID: 0034709432     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9944296     Document Type: Article

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