(1S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-hydroxyethylammonium benzoate, a versatile building block for chiral 2-aminoalkanols: Concise synthesis and application to nelfinavir, a potent HIV-protease inhibitor

Journal of Organic Chemistry

Volumn 65, Issue 6, 2000, Pages 1623-1628

  Inaba, Takashi ^a   Yamada, Yasuki ^a   Abe, Hiroyuki ^a   Sagawa, Shoichi ^a   Cho, Hidetsura ^a  

^a JAPAN TOBACCO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,2 DIMETHYL 1,3 DIOXOLAN 4 YL) 2 HYDROXYETHYLAMMONIUM BENZOATE; NELFINAVIR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG CONFORMATION; DRUG SPECIFICITY; DRUG SYNTHESIS; PROTEINASE INHIBITION; STEREOISOMERISM; STEREOSPECIFICITY;

AMINO ALCOHOLS; HIV PROTEASE INHIBITORS; NELFINAVIR; STEREOISOMERISM;

EID: 0034708584     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo991793e     Document Type: Article

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