Up-regulation of type II adenylyl cyclase mRNA in kindling model of epilepsy in rats

Neuroscience Letters

Volumn 282, Issue 3, 2000, Pages 173-176

  Iwasa, Hiroto ^a   Kikuchi, Shuichi ^b   Mine, Seiichiro ^a   Miyagishima, Hiro ^a   Sugita, Katsuo ^a   Sato, Toshio ^a   Hasegawa, Shuji ^c  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^c Chiba City Inst Hlth Environ S   (Japan)

Author keywords

Cerebral cortex; Epilepsy; G proteins; Hippocampus; Kindling; Seizure; Transmembrane signaling; Type II Adenylyl Cyclase

Indexed keywords

ADENYLATE CYCLASE; MESSENGER RNA;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; EPILEPSY; EPILEPTOGENESIS; HIPPOCAMPUS; KINDLING; MALE; MESSENGER RNA SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, NORTHERN; CEREBRAL CORTEX; EPILEPSY; HIPPOCAMPUS; KINDLING, NEUROLOGIC; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEIZURES; UP-REGULATION;

EID: 0034708531     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00897-1     Document Type: Article

References (17)

1. Chen G., Pan B., Hawver D.B., Wright C.B., Potter W.Z., Manji H.K. Attenuation of cyclic AMP production by carbamazepine. J. Neurochem. 67:1996;2079-2086.
2. Defelipe J., Marco P., Sola R.G., Sánchez-Blázquez P., Garzón J. Local changes in GTP-binding protein immunoreactivities in human epiletogenic neocortex. Exp. Brain Res. 119:1998;153-158.
3. Furuyama T., Inagaki S., Takagi H. Distribution of type II adenylyl cyclase mRNA in the rat brain. Mol. Brain Res. 19:1993;165-170.
4. Goddard G.V., McIntyer D.C., Leech C.K. A permanent change in brain function resulting from electrical stimulation. Exp. Neurol. 25:1969;295-330.
5. 3H]GTP binding in the cerebral cortical membrane. Jpn. J. Psychiatry Neurol. 42:1991;542-544.
6. Iwasa H., Hasegawa S., Kikuchi S., Watanabe K., Sato T. Amygdaloid kindling elicits persistent changes in pertussis toxin-catalyzed ADP-ribosylation. Epilepsia. 35:1994;855-860.
7. Iwasa H., Kikuchi S., Watanabe H., Hasegawa S. Altered expression levels of G protein subclass mRNAs in various seizure stages of the kindling model. Brain Res. 818:1999;570-574.
8. Iwasa H., Kikuchi S., Mine S., Sugita K., Miyagishima K., Hasegawa S. Functional significance of stimulatory GTP binding protein in hippocampus is associated with kindling-elicited epileptogenesis. Psychiatry Clin. Neurosci. 54:2000;. in press.
9. s-stimulated adenylyl cyclases. FASEB J. 7:1993;768-775.
10. Kapur J., Michelson H.B., Buterbaugh G.G., Lothman E.W. Evidence for a chronic loss of inhibition in the hippocampus after kindling: electrophysiological studies. Epilepsy Res. 4:1989;90-99.
11. s to the catalytic moiety of adenylate cyclase in a manner similar to that seen with chronic antidepressant drugs. J. Neurochem. 56:1991;330-338.
12. Pellegrino L.J.A., Pellegrino S., Cushman A.J. A Stereotaxic Atlas of the Rat Brain. 2nd edn. 1979;Plenum, New York.
13. s -stimulated adenylyl cyclases. Curr. Opin. Neurobiol. 3:1993;345-351.
14. Racine R.J. Modification of seizure activity by electrical stimulation II. Motor seizure. Electroenceph., clin. Neurophysiol. 32:1972;281-294.
15. Sambrook J., Fritch E.F., Maniatis T. Molecular Coning, 7. Extraction, Purification and Analysis of Messenger RNA from Eukariotic Cells. 2nd edn. 1989.
16. Sutula T.P. Reactive changes in epilepsy: cell death and axon sprouting induced by kindling. Epilepsy Res. 10:1991;62-70.
17. Wasterlain C.G., Farber D.B. Cyclic nucleotide response of the hippocampal formation to septal stimulation in naive and kindled rats. J. Neurochem. 47:1986;185-190.