Altered expression levels of G protein subclass mRNAs in various seizure stages of the kindling model

Brain Research

Volumn 818, Issue 2, 1999, Pages 570-574

  Iwasa, Hiroto ^a   Kikuchi, Shuichi ^b   Miyagishima, Hiro ^a   Mine, Seiichiro ^a   Koseki, Keijirou ^c   Hasegawa, Shuji ^d  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^c Matsudo Municipal Hospital   (Japan)

^d Chiba City Inst Hlth Environ S   (Japan)

Author keywords

Epilepsy; G protein; G(g) mRNA; G(i2) mRNA; Kindling; Signal transduction system

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; EPILEPTOGENESIS; KINDLING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE;

ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; EPILEPSY; GTP-BINDING PROTEINS; KINDLING, NEUROLOGIC; MALE; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0033550733     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01309-2     Document Type: Article

References (20)

1. Boehm S., Betz H. Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors. J. Neurosci. 17:1997;4066-4075.
2. Burke J.P., Hablitz J.J. G protein activation by metabotropic glutamate receptors reduced spike frequency adaptation in neocortical neurons. Neuroscience. 75:1996;123-131.
3. Casey P.J. Protein lipidation in cell signaling. Science. 268:1995;221-225.
4. βγ receptors, and effects. Cell. 73:1993;631-641.
5. i2 in amygdala-kindled rats. Synapse. 22:1996;226-231.
6. Goddard G.V., McIntyer D.C., Leech C.K. A permanent change in brain function resulting from electrical stimulation. Exp. Neurol. 25:1969;295-330.
7. Gonoi T., Mizuno N., Inagaki N., Kuromi H., Seino Y., Miyazaki J., Seino S. Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6. J. Biol. Chem. 269:1994;16989-16992.
8. Hucho F., Testlin V. Structural biology of key nervous system proteins. J. Neurochem. 66:1996;1781-1792.
9. o from rat brain. Proc. Natl. Acad. Sci. USA. 83:1986;3776-3780.
10. 3H ]GTP binding in the cerebral cortical membrane Jpn. J. Psychiatry Neurol. 45:1991;303-307.
11. Iwasa H., Hasegawa S., Kikuchi S., Watanabe K., Sato T. Amygdaloid kindling elicits persistent changes in pertussis toxin-catalyzed ADP-ribosylation. Epilepsia. 35:1994;855-860.
12. Jones D.T., Reed R.R. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. J. Biol. Chem. 263:1987;14241-14249.
13. Lasoń W., Przewłocki R. Seizure-induced expression of G proteins in the rat hippocampus. Mol. Brain Res. 24:1994;65-69.
14. i3. Biochem. J. 262:1989;403-408.
15. L.J. Pellegrino, A.S. Pellegrino, A.J. Cushman, A Stereotaxic Atlas of the Rat Brain, 2nd edn., Plenum, New York, 1979.
16. Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32:1972;281-294.
17. J. Sambrook, E.F. Fritch, T. Maniatis (Eds.), Extraction, Purification and Analysis of Messenger RNA from Eukaryotic Cells. Molecular Cloning, 2nd edn., Cold Spring Harbor, New York, 1989.
18. + channel GIRK2. Proc. Natl. Acad. Sci. USA. 94:1997;923-927.
19. Williams S.F., Colling S.B., Whittington M.A., Jefferys J.G.R. Epileptic focus induced by intrahippocampal cholera toxin in rat:time course and properties in vivo and in vitro. Epilepsy Res. 16:1993;137-146.
20. Young D., Dragunow M. Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms. Neuroscience. 58:1994;245-261.