Studies on the specificity of the tetrapyrrole substrate for human biliverdin-IXα reductase and biliverdin-IXβ reductase: Structure-activity relationships define models for both active sites

Journal of Biological Chemistry

Volumn 275, Issue 25, 2000, Pages 19009-19017

  Cunningham, Orla ^a   Dunne, Aisling ^a   Sabido, Portia ^b   Lightner, David ^b   Mantle, Timothy J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF NEVADA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIVERDIN; BILIVERDIN 9ALPHA REDUCTASE; BILIVERDIN 9BETA REDUCTASE; BUTYRIC ACID DERIVATIVE; STEROID 5ALPHA REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; HUMANS; KINETICS; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PYRROLES; RATS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TETRAPYRROLES;

EID: 0034705454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.25.19009     Document Type: Article

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