Selective inhibition of trypsin by (2R,4R)-4-phenyl-1-[N(α)-(7-methoxy- 2-naphthalenesulfonyl)-L-arginyl]-2-piperidinecarboxylic acid

Journal of Biological Chemistry

Volumn 275, Issue 25, 2000, Pages 18995-18999

  Hijikata Okunomiya, Akiko ^a   Tamao, Yoshikuni ^b   Kikumoto, Ryoji ^b   Okamoto, Shosuke ^c  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Mitsubishi Pharma Corporation   (Japan)

^c Kobe Res Projects Thromb H   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYL 1[NALPHA (7 METHOXY 2 NAPHATHALENESULFONYL) ARGINYL] 2 PIPERIDINE CARBOXYLIC ACID; ANTIPAIN; DOCKING PROTEIN; LEUPEPTIN; NAFAMSTAT MESILATE; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; DRUG BINDING; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; CHYMASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PIPECOLIC ACIDS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; SULFONAMIDES; THROMBIN; TRYPSIN; TRYPSIN INHIBITORS; TRYPTASES;

EID: 0034705404     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M908124199     Document Type: Article

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