Age-related changes of neuronal counts in the human pedunculopontine nucleus

Neuroscience Letters

Volumn 288, Issue 3, 2000, Pages 195-198

  Ransmayr, G ^a   Faucheux, B ^b   Nowakowski, C ^a   Kubis, N ^b   Federspiel, S ^a   Kaufmann, W ^a   Henin, D ^b   Hauw, J J ^c   Agid, Y ^b   Hirsch, E C ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b INSERM   (France)

^c BICHAT HOSPITAL   (France)

Author keywords

Age; Centenarian; Ch5; Choline acetyltransferase; Cholinergic; Pedunculopontine nucleus

Indexed keywords

CHOLINE ACETYLTRANSFERASE;

ADULT; AGE; AGED; ARTICLE; AUTOPSY; BRAIN NUCLEUS; CELL COUNT; CELL LOSS; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; AGING; CELL COUNT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEURONS; PONS; TEGMENTUM MESENCEPHALI;

EID: 0034698495     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01244-1     Document Type: Article

References (20)

1. Abercrombie M. Estimation of nuclear population from microtomic sections. Anat. Rec. 94:1946;239.
2. Arendt T., Brückner M.K., Bigl V., Marcova L. Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. III. The basal forebrain compared with other subcortical areas. J. Comp. Neurol. 351:1995;223-246.
3. Geula C., Mesulam M.-M. Cholinergic systems and related neuropathological predilection patterns in Alzheimer's disease. Terry R.D., Katzman R., Bick K.L. Alzheimer Disease. 1994;263-291 Raven Press, New York.
4. Geneser-Jensen F.A. Distribution of acetylcholinesterase in the hippocampal region of the guinea pig. I. Subiculum and hippocampus. Z. Zellforsch. 124:1972;546-560.
5. Hirsch E.C., Graybiel A.M., Duyckaerts C., Javoy-Agid F. Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy. Proc. Natl. Acad. Sci. USA. 84:1987;5976-5980.
6. Jellinger K. The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry. 51:1988;540-543.
7. Kubis N., Faucheux B.A., Ransmayr G., Damier P., Duyckaerts C., Henin D., Forette B., Le Charpentier Y., Hauw J.-J., Agid Y., Hirsch E.C. Preservation of midbrain catecholaminergic neurons in very old human subjects. Brain. 123:2000;366-373.
8. Manaye K.F., Zweig R., Wu D., Hersh L.B., De Lacalle S., Saper C.B., German D.C. Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain. Neuroscience. 89:1999;759-770.
9. McGeer P.L., McGeer E.G., Suzuki J., Dolman C.E., Nagai T. Aging. Alzheimer's disease, and the cholinergic system of the basal forebrain. Neurology. 34:1984;741-745.
10. Mestre N., Bons N. Age-related cytological changes and neuronal loss in basal forebrain cholinergic neurons in Microcebus murinus (Lemurian, Primate). Neurodegeneration. 2:1993;25-32.
11. Mesulam M.-M., Mufson E.J., Wainer B.H., Levey A.I. Central cholinergic pathways in the rat: an overview based on alternative nomenclature (Ch1-Ch6). Neuroscience. 10:1983;1185-1201.
12. Mirra S.S., Heyman A., McKeel D., Sumi S.M., Crain B.J., Brownlee L.M., Vogel F.S., Hughes J.P., van Belle G., Berg L. The consortium to establish a registry for Alzheimer's disease (CERDA) Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
13. Mizukawa K., McGeer P.L., Tago H., Peng J.H., McGeer E.G., Kimura H. The cholinergic system of the hindbrain studied by choline acetyltransferase immunohistochemistry and acetylcholineesterase histochemistry. Brain Res. 379:1986;39-55.
14. Moon Edley S., Graybiel A.M. The afferent and efferent connections of the feline nucleus tegmenti pedunculopontinus, pars compacta. J. Comp. Neurol. 217:1983;187-215.
15. Mufson E.J., Mash D.C., Hersh L.B. Neurofibrillary tangles in the cholinergic pedunculopontine neurons in Alzheimer's disease. Ann. Neurol. 24:1988;623-629.
16. Olszewski J., Baxter D. Cytoarchitecture of the Human Brain Stem. 1954;48-53 Karger, Basel.
17. Tagliavini F., Pilleri G., Gemignani F., Lechi A. Neuronal loss in the basal nucleus of Meynert in progressive supranuclear palsy. Acta Neuropathol. 61:1983;157-160.
18. Whitehouse P.J., Hedreen J.C., White C.L. III, Price D.L. Basal forebrain neurons in the dementia of Parkinson disease. Ann. Neurol. 13:1983;243-248.
19. Woolf N.J., Jacob R.W., Butcher L.L. The pontomesencephalotegmental cholinergic system does not degenerate in Alzheimer's disease. Neurosci. Lett. 96:1989;277-282.
20. Zweig R.M., Whitehouse P.J., Casanova M.F., Walker L.C., Jankel W.R., Price D.L. Loss of pedunculopontine neurones in progressive supranuclear palsy. Ann. Neurol. 22:1987;18-25.