Activation of nitric oxide synthase by ischaemia in the perfused heart

Cardiovascular Research

Volumn 33, Issue 1, 1997, Pages 82-87

  Depré, Christophe ^a   Fiérain, Lionel ^a   Hue, Louis ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

cGMP; myocardial ischemia; nitric oxide; nitric oxide synthase; rabbit, heart; reperfusion

Indexed keywords

CYCLIC GMP; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; ISOLATED HEART; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RABBIT; VASODILATATION;

ANIMALS; ARGININE; CELL MEMBRANE; CITRULLINE; CYTOSOL; ENZYME ACTIVATION; ISOENZYMES; MALE; MYOCARDIAL ISCHEMIA; NITRIC OXIDE SYNTHASE; PERFUSION; RABBITS;

EID: 0031023395     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(96)00176-9     Document Type: Article

References (35)

1. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide; physiology pathophysiology and pharmacology. Pharmacol Rev. 43:1991;109-142.
2. Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem. 63:1994;175-195.
3. Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 327:1987;524-526.
4. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA. 84:1987;9265-9269.
5. Balligand JL, Kelly RA, Marsden PA, Smith TW, Michel T. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA. 90:1993;347-351.
6. Brady AJ, Warren JB, Poole-Wilson PA, Williams TJ, Harding SE. Nitric oxide attenuates cardiac myocyte contraction. Am J Physiol. 265:1993;H176-H182.
7. 2+-independent nitric oxide synthase in the myocardium. Br J Pharmacol. 105:1992;575-580.
8. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 257:1992;387-389.
9. Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J. 298:1994;249-258.
10. Smith TP, Canty JM. Modulation of coronary autoregulatory responses by nitric oxide. Circ Res. 73:1992;232-240.
11. Offstad P, Naess PA, Aksnes G, Tonnessen T, Ilebekk A, Kirkeboen KA. Nitric oxide regulates coronary blood flow at various coronary arterial pressures in intact porcine hearts. Acta Physiol Scand. 154:1995;93-102.
12. Walter U. Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system. Rev Physiol Biochem Pharmacol. 113:1989;41-88.
13. Depré C, Hue L. Cyclic GMP in the perfused rat heart. Effect of ischemia, anoxia and nitric oxide synthase inhibitor. FEBS Lett. 345:1994;241-245.
14. Depré C, Vanoverschelde J-L, Goudemant J-F, Mottet I, Hue L. Protection against ischemic injury by non-vasoactive concentrations of nitric oxide synthase inhibitors in the perfused rabbit heart. Circulation. 92:1995;1911-1918.
15. Vanoverschelde JL, Janier MF, Bergmann SR. The relative importance of myocardial energy metabolism compared with ischemic contracture in the determination of ischemic injury in isolated perfused rabbit hearts. Circ Res. 74:1994;817-828.
16. Hearse DJ, Garlick PB, Humphrey SM. Ischemic contracture of the myocardium: mechanism and prevention. Am J Cardiol. 39:1977;986-993.
17. Knowles RG, Merrett M, Salter M, Moncada S. Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem J. 270:1990;833-836.
18. Bredt DS, Snyder SH. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme. Proc Natl Acad Sci USA. 87:1990;682-685.
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 193:1951;265-275.
20. Forstermann U, Schmidt HH, Pollock JS, et al. Isoforms of nitric oxide synthase. Biochem Pharmacol. 42:1991;1849-1857.
21. Griffiths MJD, Messent M, MacAllister RJ, Evans TN. Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br J Pharmacol. 110:1993;963-968.
22. Misko TP, Moore WM, Kasten TP, et al. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol. 233:1993;119-125.
23. Xu XP, Pollock JS, Tanner MA, Myers PR. Hypoxia activates nitric oxide synthase and stimulates nitric oxide production in porcine coronary resistance arteriolar endothelial cells. Cardiovasc Res. 30:1995;841-847.
24. Node K, Kitakaze M, Kosaka H, et al. Plasma nitric oxide end-products are increased in the ischemic canine heart. Biochem Biophys Res Commun. 211:1995;370-374.
25. Kitakaze M, Node K, Komamura K, et al. Evidence for nitric oxide generation in the cardiomyocytes: its augmentation by hypoxia. J Mol Cell Cardiol. 27:1995;2149-2154.
26. Lamas S, Marsden PA, Li GK, Temps TP, Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive isoform. Proc Natl Acad Sci USA. 89:1992;6348-6352.
27. Drapier JC, Hibbs JB. Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of iron-sulfur enzymes in the macrophage effector cells. J Immunol. 140:1988;2829-2838.
28. Stuehr DJ, Kwon NS, Gross SS, Thiel BA, Levi R, Nathan CF. Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components. Biochem Biophys Res Commun. 161:1989;420-426.
29. Stuehr DJ, Cho HJ, Kwon NS, Weise MF, Nathan CF. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc Natl Acad Sci USA. 88:1991;7773-7777.
30. 2+-independent nitric oxide synthases. FEBS Lett. 291:1991;145-149.
31. Balligand JL, Kobzik L, Han X, et al. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J Biol Chem. 270:1995;14582-14586.
32. Brown IP, Thompson CI, Belloni FL. Role of nitric oxide in hypoxic coronary vasodilatation in isolated perfused guinea pig heart. Am J Physiol. 264:1993;H821-H829.
33. Park KA, Rubin LE, Gross SS, Levi R. Nitric oxide is a mediator of hypoxic coronary vasodilatation. Circ Res. 71:1992;992-1001.
34. Duncker DJ, Bache RJ. Inhibition of nitric oxide production aggravates myocardial hypoperfusion during exercise in the presence of a coronary artery stenosis. Circ Res. 74:1994;629-640.
35. m for oxygen of nitric oxide synthase isoforms. J Pharmacol Exp Ther. 276:1996;30-33.