Mirroring perfection: The structure of methylglyoxal synthase complexed with the competitive inhibitor 2-phosphoglycolate

Biochemistry

Volumn 39, Issue 11, 2000, Pages 2950-2960

  Saadat, Dana ^a   Harrison, David H T ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOLIC ACID DERIVATIVE; METHYLGLYOXAL; SYNTHETASE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENANTIOMER; ENZYME STRUCTURE; MODEL; PRIORITY JOURNAL; PROTEIN FOLDING; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BINDING SITES; BINDING, COMPETITIVE; CARBON-OXYGEN LYASES; CRYSTALLIZATION; ENZYME INHIBITORS; GLYCOLATES; MODELS, MOLECULAR; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRIOSE-PHOSPHATE ISOMERASE;

EID: 0034696583     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992666f     Document Type: Article

References (59)

1. Albery, W. J., and Knowles, J. R. (1976) Biochemistry 15, 5631-5640.
2. Stamper, C. G., Morollo, A. A., and Ringe, D. (1998) Biochemistry 37, 10438-10445.
3. Sugio, S., Petsko, G. A., Manning, J. M., Soda, K., and Ringe, D. (1995) Biochemistry 34, 9661-9669.
4. Okamoto, A., Nakai, Y., Hayashi, H., Hirotsu, K., and Kagamiyama, H. (1998) J. Mol. Biol. 280, 443-461.
5. Momany, C., Ghosh, R., and Hackert, M. L. (1995) Protein Sci. 4, 849-854.
6. Summers, M. C., and Rose, I. A. (1977) J. Am. Chem. Soc. 99, 4475-4478.
7. Saadat, D., and Harrison, D. H. T. (1998) Biochemistry 37, 10074-10086.
8. Yuan, P. M., and Gracy, R. W. (1971) Arch. Biochem. Biophys. 183, 1-6.
9. Cooper, R. A., and Anderson, A. (1970) FEBS Lett. 11, 273-276.
10. Cooper, R. A. (1984) Annu. Rev. Microbiol. 44, 812-826.
11. Rahman, A., Shahabuddin, M., and Hadi, S. M. (1990) J. Biochem. Toxicol. 5, 161-166.
12. Papoulis, A., al-Abed, Y., and Bucala, R. (1995) Biochemistry 34, 648-655.
13. Baskaran, S., and Balasubramanian, K. A. (1990) Biochem. Int. 21, 165-174.
14. Együd, L. G., and Szent-Györgyi, A. (1966) Proc. Natl. Acad. U.S.A. 56, 203-207.
15. Clelland, J. D., and Thornalley, P. J. (1993) Biochem. Soc. Trans. 21, 160S.
16. Hopper, D. J., and Cooper, R. A. (1972) Biochem. J. 128, 321-329.
17. Tötemeyer, S., Booth, N. A., Nichols, W. W., Dunbar, B., and Booth, I. R. (1998) Mol. Microbiol. 27, 553-562.
18. Brownlee, M., and Cerami, A. (1981) Annu. Rev. Biochem. 50, 385-432.
19. Murthy, N. S., Bakeris, T., Kavarana, M. J., Hamilton, D. S., Lan, Y., and Creighton, D. J. (1994) J. Med. Chem. 37, 2161-2166.
20. Cameron, D. C., Altaras, N. E., Hoffman, M. L., and Shaw, A. J. (1998) Biotechnol. Prog. 14, 116-125.
21. Saadat, D., and Harrison, D. H. T. (1999) Struct. Folding Des. 7, 309-317.
22. Lolis, E., and Petsko, G. A. (1990) Biochemistry 29, 6619-6625.
23. Otwinowski, Z., and Minor, W. (1996) (Carter, C., and Sweet, R. M., Eds.) pp 307-325, Academic Press, Boston.
24. Brünger, A. T. (1992) X-PLOR Version 3.1, A system for X-ray crystallography and NMR, version 3.1, Yale University Press, New Haven, CT.
25. Brünger, A. T. (1992) Nature 355, 472-474.
26. Kleywegt, G. J., and Jones, T. A. (1996) Acta Crystallogr., Sect. D 52, 826-828.
27. Kleywegt, G. J., and Jones, T. A. (1995) Structure 3, 535-540.
28. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr., Sect. A 47, 110-119.
29. Honig, B., Sharp, K., and Yang, A.-S. (1993) J. Phys. Chem. 97, 1101.
30. Nichols A., Bharadwaj, R., and Honig, B. (1993) Biophysical 64, 166-170.
31. Campbell, I. D., Jones, R. B., Kiener, P. A., Richards, E., Waley, S. C., and Wolfenden, R. (1978) Biochem. Biophys. Res. Commun. 83, 347-352.
32. Richard, J. P. (1998) Biochemistry 37, 4305-4309.
33. Hall, A., and Knowles, J. R. (1975) Biochemistry 14, 4348-4353.
34. Iyengar, R., and Rose, I. A. (1983) J. Am. Chem. Soc. 105, 3301-3303.
35. Richard, J. P. (1984) J. Am. Chem. Soc. 106, 4926-4936.
36. Richard, J. P. (1991) Biochemistry 30, 4581-4585.
37. Richard, J. P. (1993) Biochem. Soc. Trans. 21, 549-553.
38. Davenport, R. C., Bash, P. A., Seaton, B. A., Karplus, M., Petsko, G. A., and Ringe, D. (1991) Biochemistry 30, 5821-5826.
39. Plaut, B., and Knowles, J. R. (1972) Biochem. J. 129, 311-320.
40. Fisher, L. M., Albery, W. J., and Knowles, J. R. (1976) Biochemistry 15, 5621-5626.
41. Leadlay, P. F., Albery, W. J., and Knowles, J. R. (1976) Biochemistry 15, 5617-5620.
42. Komives, E. A., Chang, L. C., Lolis, E., Tilton, R. F., Petsko, G. A., and Knowles, J. R. (1991) Biochemistry 30, 3011-3019.
43. Webb, M. R., and Knowles, J. R. (1975) Biochemistry 14, 4692-4698.
44. Bash, P. A., Field, M. J., Davenport, R. C., Petsko, G. A., Ringe, D., and Karplus, M. (1991) Biochemistry 30, 5826-5832.
45. Joseph-McCarthy, D., Lolis, E., Komives, E. A., and Petsko, G. A. (1994) Biochemistry 33, 2815-2823.
46. Lodi, P. J., Chang, L. C., Knowles, J. R., and Komives, E. A. (1994) Biochemistry 33, 2809-2814.
47. Harris, T. K., Abeygunawardana, C., and Mildvan, A. S. (1997) Biochemistry 36, 14661-14675.
48. Harris, T. K., Cole, R. N., Comer, F. I., and Mildvan, A. S. (1998) Biochemistry 37, 16828-16838.
49. Belasco, J. G., Herlihy, J. M., and Knowles, J. R. (1978) Biochemistry 17, 2971-2978.
50. Alber, T. C., Davenport, R. C., Jr., Giammona, D. A., Lolis, E., Petsko, G. A., and Ringe, D. (1987) Cold Spring Harbor Symp. Quant. Biol. 52, 603-613.
51. Deslongchamps, P., Atlani, P., Frehel, D., and Malaval, A. (1972) Can. J. Chem. 50, 3405-3408.
52. Kirby, A. J. (1983) The Anomeric Effect and Related Stereo-electronic Effects at Oxygen, Springer-Verlag, Berlin.
53. Rose, I. A. (1981) Philos. Trans R. Soc. London, Series B: Biol. Sci. 293, 131-143.
54. Leoncini, G., Maresca, M., Ronchi, S., and Bonsignore, A. (1979) It. J. Biochem. 28, 232-244.
55. Kalyananda, M. K., Engel, R., and Tropp, B. E. (1987) J. Bacteriol. 169, 2488-2493.
56. Tang, C.-T., Engel, R., and Tropp, B. E. (1999) Antimicrob. Agents Chemother. 11, 147-153.
57. Pompliano, D. L., Peyman, A., and Knowles, J. R. (1990) Biochemistry 29, 3186-3194.
58. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 548-558.
59. Engh, R. A. and Huber, R. (1998) Acta Crystallogr., Sect. A 47, 392-400.