2-Methyladenosine-substituted 2',5'-oligoadenylates: Conformations, 2-5A binding and catalytic activities with human ribonuclease L

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 4, 2000, Pages 329-331

  Kitade, Yukio ^a   Wakana, Masaharu ^a   Tsuboi, Takayuki ^a   Yatome, Chizuko ^a   Bayly, Suzanne F ^b   Player, Mark R ^b   Torrence, Paul F ^c  

^a Laboratory of Molecular Biochemistry   (Japan)

^b Human Motor Control Section   (United States)

^c NORTHERN ARIZONA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLIC ACID; ADENOSINE DERIVATIVE; DRUG ANALOG; LEAD; OLIGOMER; RIBONUCLEASE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CHEMICAL MODIFICATION; CONFORMATION; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; PARTIAL DRUG SYNTHESIS;

ADENOSINE; ADENOSINE MONOPHOSPHATE; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; ENDORIBONUCLEASES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034696057     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00703-9     Document Type: Article

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