The S-alkyl chain length as a determinant of the anti-leukemic activity of cysteine chloromethyl ketone compounds

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 6, 2000, Pages 551-552

  Perrey, David A ^a   Scannell, Michael P ^a   Narla, Rama Krishna ^a   Uckun, Fatih M ^a  

^a Parker Hughes Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; CYSTEINE CHLOROMETHYL KETONE; KETONE DERIVATIVE; N ACETYL S DODECYL CYSTEINE CHLOROMETHYL KETONE; N ACETYL S HEXYL CYSTEINE CHLOROMETHYL KETONE; N ACETYL S UNDECYL CYSTEINE CHLOROMETHYL KETONE; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; B LYMPHOBLAST; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; STRUCTURE ACTIVITY RELATION; T LYMPHOBLAST;

ALKYLATION; ANTINEOPLASTIC AGENTS; CELL LINE; COLORING AGENTS; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLIUM SALTS; THIAZOLES; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034689169     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00047-0     Document Type: Article

References (5)

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