Application of Grignard reagents to the synthesis of tertiary methylamines via resin-bound oxyiminium ions

Tetrahedron Letters

Volumn 41, Issue 34, 2000, Pages 6639-6642

  Blaney, Paul ^a   Grigg, Ronald ^a   Rankovic, Zoran ^b   Thoroughgood, Matthew ^b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Benzotriazole Mannich adducts; Grignard reagents; Ions; Oxyiminium; Solid phase synthesis; Tertiary methylamines; Traceless hydroxylamine linker; Tramadol; methylpargyline

Indexed keywords

ANALGESIC AGENT; HYDROXYLAMINE; METHYLAMINE; MONOAMINE OXIDASE INHIBITOR; PARGYLINE; REAGENT; RESIN; TRAMADOL;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REACTION ANALYSIS;

EID: 0034686884     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)01104-7     Document Type: Article

References (14)