Differential distribution of voltage-gated sodium channel α- and β-subunits in human brain

Annals of the New York Academy of Sciences

Volumn 868, Issue , 1999, Pages 88-92

  Whitaker, W R J ^a   Clare, J J ^b   Emson, P C ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SODIUM CHANNEL;

CEREBELLUM; CHANNEL GATING; CONFERENCE PAPER; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; OLIGONUCLEOTIDE PROBE; PROTEIN LOCALIZATION; RNA SPLICING;

EID: 0033008828     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb11278.x     Document Type: Conference Paper

References (12)

1. Catterall, W.A. 1992. Cellular and molecular biology of voltage-gated sodium channels. Physiol. Rev. 72(4): S15-S48.
2. Noda, M. et al. 1986. Expression of functional sodium channels from cloned cDNA. Nature 322: 826-828.
3. + channel α-subunit with novel gating properties. Neuron 1: 449-461.
4. Kayano, T. et al. 1988. Primary structure of rat brain sodium channel type III deduced from the cDNA sequence. FEBS Lett. 228: 187-194.
5. Schaller, K.L. et al. 1995. Alternatively spliced sodium channel transcripts in brain and muscle. J. Neurosci. 15(5): 3231-3242.
6. Hartshorne R.P. & W.A. Catterall. 1984. The sodium channel from rat brain: Purification and subunit composition. J. Biol. Chem. 259: 1667-1675.
7. II sodium channel subtypes. Proc. Natl. Acad. Sci. USA 84: 8682-8686.
8. Felts, P.A. et al. 1997. Sodium channel α-subunit expression patterns in developing rat nervous system. Mol. Brain. Res. 45: 71-82.
9. + channel β1 subunit mRNA in rat CNS neurons. Neurosci. Lett. 176: 119-122.
10. Schaller, K.L. et al. 1992. A novel sodium channel expressed in neurons and glia. J. Neurosci. 12(4): 1370-1381.
11. Smith, R.D. & A.I.. Goldin. 1998. Functional analysis of the rat I sodium channel in Xenopus oocytes. J. Neurosci. 18(3): 811-820.
12. Raman, I.M. et al. 1997. Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice. Neuron 19: 881-891.