Squamous differentiation downregulates Muc1 mucin in hamster tracheal surface epithelial cell

Biochemical and Biophysical Research Communications

Volumn 271, Issue 3, 2000, Pages 641-646

  Shin, Chan Young ^a   Park, Kyu Hwan ^a   Ryu, Byung Kwon ^a   Choi, Eui Yul ^b   Kim, Kwang Chul ^c   Ko, Kwang Ho ^a  

^a Seoul National University   (South Korea)

^b Hallym University   (South Korea)

^c UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Hamster tracheal Muc1 mucin; Monoclonal antibody; Retinoic acid deficiency; Squamous differentiation

Indexed keywords

HYBRID PROTEIN; MONOCLONAL ANTIBODY; MUCIN; RETINOIC ACID;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; IMMUNOREACTIVITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL; TRACHEA MUCOSA; WESTERN BLOTTING;

ANIMALIA; CRICETINAE;

EID: 0034685638     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2689     Document Type: Article

References (28)

1. Siddiqui, J., Abe, M., Hayes, D., Shani, E., Yunis, E., and Kufe, D. (1988) Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen. Proc. Natl. Acad. Sci. USA 85, 2320-2323.
2. Jeffery, P. K., and Li, D. (1997) Airway mucosa: secretory cells, mucus and mucin genes. Eur. Respir. J. 10, 1655-1662.
3. Park, H., Hyun, S. W., and Kim, K. C. (1996) Expression of MUC1 mucin gene by hamster tracheal surface epithelial cells in primary culture. Am. J. Respir. Cell. Mol. Biol. 15, 237-244.
4. Pemberton, L., Papadimitriou, J. T., and Gendler, S. J. (1992) Antibodies to the cytoplasmic domain of the MUC1 mucin show conservation throughout mammals. Biochem. Biophys. Res. Commun. 185, 167-175.
5. Strous, G. J., and Dekker, J. (1992) Mucin-type glycoproteins. Crit. Rev. Biochem. Mol. Biol. 27, 57-92.
6. Aplin, J. D., Seif, M. W., Graham, R. A., Hey, N. A., Behzad, F., and Campbell, S. (1994) The endometrial cell surface and implantation: Expression of the polymorphic mucin MUC-1 and adhesion molecules during the endometrial cycle. Ann. NY Acad. Sci. 734, 103-121.
7. Kim, K. C., Wasano, K., Niles, R. M., Schuster, J. E., Stone, P. J., and Brody, J. S. (1987) Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells. Proc. Natl. Acad. Sci. USA 84, 9304-9308.
8. Varsano, S., Basbaum, C. B., Forsberg, L. S., Borson, D. B., Caughey, G., and Nadel, J. A. (1987) Dog tracheal epithelial cells in culture synthesize sulfated macromolecular glycoconjugates and release them from the cell surface upon exposure to extracellular proteinases. Exp. Lung Res. 13, 157-184.
9. Batra, S. K., Kern, H. F., Worlock, A. J., Metzgar, R. S., and Hollingswort, M. A. (1991) Transfection of the human Muc 1 mucin gene into a poorly differentiated human pancreatic tumor cell line, Panel: Integration, expression and ultrastructural changes. J. Cell. Sci. 100, 841-849.
10. Gendler, S. J., Spicer, A. P., Lalani, E. N., Duhig, T., Peat, N., Burchell, J., Pemberton, L., Boshell, M., and Taylor-Papadimitriou, J. (1991) Structure and biology of a carcinoma-associated mucin, MUC1. Am. Rev. Respir. Dis. 144, S42-S47.
11. Parry, G., Li, J., Stubbs, J., Bissell, M. J., Schmidhauser, C., Spicer, A. P., and Gendler, S. J. (1992) Studies of Muc-1 mucin expression and polarity in the mouse mammary gland demonstrate developmental regulation of Muc-1 glycosylation and establish the hormonal basis for mRNA expression. J. Cell. Sci. 101, 191-199.
12. Guzman, K., Randell, S. H., and Nettesheim, P. (1995) Epidermal growth factor regulates expression of the mucous phenotype of rat tracheal epithelial cells. Biochem. Biophys. Res. Commun. 217, 412-418.
13. Jetten, A. M., Brody, A. R., Deas, M. A., Hook, G. E. R., Rearick, J. I., and Thacher, S. M. (1987) Retinoic acid and substratum regulate the differentiation of rabbit tracheal epithelial cells into squamous and secretory phenotype. Lab. Invest. 56, 654-664.
14. Koo, J. S., Yoon, J. H., Gray, T., Norford, D., Jetten, A. M., and Nettesheim, P. (1999) Restoration of the mucous phenotype by retinoic acid in retinoid-deficient human bronchial cell cultures: Changes in mucin gene expression. Am. J. Respir. Cell. Mol. Biol. 20, 43-52.
15. Bernacki, S. H., Nelson, A. L., Abdullah, L., Sheehan, J. K., Harris, A., William Davis, C., and Randell, S. H. (1999) Mucin gene expression during differentiation of human airway epithelia in vitro. Muc4 and muc5b are strongly induced. Am. J. Respir. Cell. Mol. Biol. 20, 595-604.
16. Shin, C. Y., Kang, S. J., Song, M. R., Park, K. H., Seo, D. O., Cheong, J. H., and Ko, K. H. (1998) Cross-species reactivity of a monoclonal antibody against glutathione S-transferase fusion protein of human β2-adrenergic receptor. Biochem. Mol. Biol. Int. 45, 215-225.
17. Shin, C. Y., Choi, E. Y., Kim, K. C., and Ko, K. H. (1998) Production and characterization of monoclonal antibodies against rat tracheal mucins. Hybridoma 17, 257-266.
18. Towbin, H., Staehelin, T., and Gordon, T. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
19. Wasano, K., Kim, K. C., Niles, R. M., and Brody, S. D. (1988) Membrane differentiation markers of airway epithelial secretory cells. J. Histochem. Cytochem. 36, 167-178.
20. Jo, M.-J., Shin, C. Y., Song, M.-R., Park, K. H., and Ko, K. H. (1999) A monoclonal antibody against hamster tracheal mucin which recognize N-acetyl-galactosamine containing carbohydrate chains as an epitope. Hybridoma 18, 449-456.
21. Shin, C. Y., Kang, S-J., Kim, K. C., and Ko, H. K. (1998) Comparison between ELISA and gel-filtration assay for the quantitation of airway mucins. Arch. Pharm. Res. 21, 253-259.
22. Xing, P. X., Lees, C., Lodding, J., Prenzoska, J., Poulos, G., Sandrin, M., Gendler, S., and McKenzie, I. F. (1998) Mouse mucin 1 (MUC1) defined by monoclonal antibodies. Int. J. Cancer 76, 875-883.
23. Smith, D. B., and Johnson, K. S. (1988) Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. GENE 67, 31-40.
24. Zrihan-Licht, S., Baruch, A., Elroy-Stein, O., Keydar, I., and Wreschner, D. H. (1994) Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules. FEBS Lett. 356, 130-136.
25. Spicer, A. P., Parry, G., Patton, S., and Gendler, S. J. (1991) Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism. J. Biol. Chem. 266, 15099-15109.
26. Vos, H. L., Vries, Y., and Hilkens, J. (1991) The mouse episialin-(MUC1) gene and its promoter: Rapid evolution of the repetitive domain in the protein. Biochem. Biophys. Res. Commun. 181, 121-130.
27. Nettesheim, P., Jetten, A. M., Inayama, Y., Brody, A. R., George, M. A., Gilmore, L. B., Gray, T., and Hook, G. E. R. (1990) Pathways of differentiation of airway epithelial cells. Environ. Health Perspect. 85, 317-329.
28. Rearick, J. I., and Jetten, A. M. (1989) Effect of substratum and retinoids upon the mucosecretory differentiation of airway epithelial cells in vitro. Environ. Health Perspect. 80, 229-237.