Michael adducts of ascorbic acid as inhibitors of protein phosphatase 2A and inducers of apoptosis

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 14, 2000, Pages 1605-1608

  Fathi, A R ^a   Krautheim, A ^a   Kaap, S ^b   Eger, K ^b   Steinfelder, H J ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID DERIVATIVE; CARBONYL DERIVATIVE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; STYRENE DERIVATIVE; VINBLASTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL VIABILITY; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; DRUG INHIBITION; DRUG SYNTHESIS; ENZYME ACTIVITY; HAMSTER; NONHUMAN;

ANIMALS; APOPTOSIS; ASCORBIC ACID; CASPASE 3; CASPASES; CELL LINE; CRICETINAE; DNA FRAGMENTATION; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITORS; INDICATORS AND REAGENTS; KINETICS; MOLECULAR STRUCTURE; PHOSPHOPROTEIN PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034679647     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00294-8     Document Type: Article

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